文献类型：期刊文献

英文题名：Palladium-Catalyzed Electrochemical C-H Alkylation of Arenes

作者：Yang, Qi-Liang[1,2,3];Li, Chuan-Zeng[3,4];Zhang, Liang-Wei[3];Li, Yu-Yan[4];Tong, Xiaofeng[1,2];Wu, Xin-Yan[1,2];Mei, Tian-Sheng[3]

机构：[1]East China Univ Sci & Technol, Key Lab Adv Mat, Sch Chem & Mol Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Inst Fine Chem, Sch Chem & Mol Engn, 130 Meilong Rd, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, State Key Lab Organometall Chem, Ctr Excellence Mol Synth, Shanghai Inst Organ Chem, 345 Lingling Lu, Shanghai 200032, Peoples R China;[4]China Pharmaceut Univ, Dept Med Chem, Nanjing 210009, Jiangsu, Peoples R China

年份：2019

卷号：38

期号：6

起止页码：1208

外文期刊名：ORGANOMETALLICS

收录：;EI(收录号：20184205950225);WOS:【SCI-EXPANDED(收录号:WOS:000462944200005)，CCR-EXPANDED(收录号:WOS:000462944200005)】；

基金：This work was financially supported by the Strategic Priority Research Program of the Chinese Academy of Sciences (Grant XDB20000000), "1000-Youth Talents Plan", NSF of China (Grants 21572245, 21772222, 21772220), and S&TCSM of Shanghai (Grants 17JC1401200, 18JC1415600).

语种：英文

外文关键词：Catalyst deactivation - Palladium - Catalysis

摘要：Palladium-catalyzed electrochemical C-H functionalization reactions have emerged as attractive tools for organic synthesis. This process offers an alternative to conventional methods that require harsh chemical oxidants. However, this electrolysis requires divided cells to avoid catalyst deactivation by cathodic reduction. Herein, we report the first example of palladium-catalyzed electrochemical C-H alkylation of arenes using undivided electrochemical cells in water, thereby providing a practical solution for the introduction of alkyl groups into arenes.