文献类型：期刊文献

英文题名：Degradation of chiral neonicotinoid insecticide cycloxaprid in flooded and anoxic soil

作者：Liu, Xuanqi[1];Xu, Xiaoyong[1];Li, Chao[1];Zhang, Hanxue[2];Fu, Qiuguo[2];Shao, Xusheng[1];Ye, Qingfu[2];Li, Zhong[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China;[2]Zhejiang Univ, Inst Nucl Agr Sci, Hangzhou 310029, Zhejiang, Peoples R China

年份：2015

卷号：119

起止页码：334

外文期刊名：CHEMOSPHERE

收录：;EI(收录号：20145200381876);WOS:【SCI-EXPANDED(收录号:WOS:000347739600045)】；

基金：This work was financial supported by National Basic Research Program of China (973 Program, 2010CB126100), the Fundamental Research Funds for the Central Universities and Special Fund for Agro-scientific Research in the Public Interest (201103007). This work was also partly supported by National High Technology Research and Development Program of China (863 Program, 2011AA10A207)

语种：英文

外文关键词：Cycloxaprid; Chiral; Isotope labeling; Soil degradation; Dynamic; Pathway

摘要：Cycloxaprid (CYC), with two stereogenic centers from oxabridged ring, is a novel potent neonicotinoid insecticide. The investigation of relevant transformation products (TPs) is critical for the risk evaluation of CYC on environment impact and further regulatory decisions. In this study, stereoselective soil metabolism of CYC enantiomers was investigated using isotope labeling techniques. Liquid scintillation counting with LC-MS/MS was used to identify and quantify the major transformation products (TPs) of CYC enantiomers in four various soils under anoxic and flooded condition. Most of CYC had been transformed in four soils at 5 d after treatment. Furthermore, CYC was found converted to a range of transformation products, which exhibited soil-specific dynamic changes. Cleavage of the oxabridged seven-member ring, reductive dechlorination in the chloropyridinyl and cleavage of C-N between the chloropyridinylmethyl and imidazalidine ring are the main transformation pathways of CYC. It is presumed that acidic condition may conduce to form the cleavage product of oxabridged seven-member ring. However, abiotic or biotic stereoselective persistence of TPs in all soils was not observed from the experimental data and may be attributed to the unstable oxabridged ring. (C) 2014 Elsevier Ltd. All rights reserved.