文献类型：期刊文献

英文题名：Divergent Synthesis of Imidazoles and Quinazolines via Pd(OAc)2-Catalyzed Annulation of N-Allylamidines

作者：Xu, Li[1,2];Li, Hongxian[1,2];Liao, Ziyang[1,2];Lou, Kaiyan[1,2];Xie, Hexin[1,2];Li, Hao[1,2];Wang, Wei[1,2,3]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab New Drug Design, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, State Key Lab Bioengn Reactor, Shanghai 200237, Peoples R China;[3]Univ New Mexico, Dept Chem & Chem Biol, Albuquerque, NM 87131 USA

年份：2015

卷号：17

期号：14

起止页码：3434

外文期刊名：ORGANIC LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000358395500015)，CCR-EXPANDED(收录号:WOS:000358395500015)】；

基金：Financial support of this research from the Eastern Scholar program at Shanghai Institutions of Higher Learning (No. 201226, H.L.), the National Science Foundation of China (No. 21372073, W.W.), and the Fundamental Research Funds for the Central Universities and the China 111 Project (Grant B07023, H.L. and W.W.) is gratefully acknowledged.

语种：英文

摘要：A Pd(OAc)(2)-catalyzed divergent synthesis of multisubstituted imidazoles and quinazolines from N-allylamidines has been developed. In the presence of oxidant O-2 from air and/or a ligand and Pd(OAc)(2) imidazoles were obtained. Nonetheless, under microwave (MW) irradiation in a sealed system, quinazolines as major products were produced.