文献类型：期刊文献

英文题名：One-pot three-component access to 5-hydroxyindoles based on an oxidative dearomatization strategy

作者：Qiu, Hong[1,2];Tong, Lingfeng[1,2];Lin, Zhongren[1,2];Li, Zheyao[1,2];Ren, Haosong[1,2];Wang, Teng[3];Yu, Xinhong[1,2]

机构：[1]East China Univ Sci & Technol, Engn Res Ctr Pharmaceut Proc Chem, Minist Educ, Shanghai Key Lab New Drug Design,Sch Pharm, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, State Key Lab Bioengn Reactors, Shanghai 200237, Peoples R China;[3]Beijing Inst Petrochem Technol, Coll Chem Engn, Beijing 102617, Peoples R China

年份：2022

卷号：20

期号：36

起止页码：7241

外文期刊名：ORGANIC & BIOMOLECULAR CHEMISTRY

收录：;EI(收录号：20223912811957);WOS:【SCI-EXPANDED(收录号:WOS:000850511300001)，CCR-EXPANDED(收录号:WOS:000850511300001)】；

基金：We gratefully acknowledge financial support from the National Natural Science Foundation of China (No. 21476078, X.-H. Y.) and the Science and Technology Commission of Shanghai Municipality (No. 12431900902, X.-H. Y.).

语种：英文

摘要：A one-pot three-component reaction based on an oxidative dearomatization strategy has been performed to provide facile access to 5-hydroxyindole derivatives through a ZnI2-catalyzed tandem process. The multi-unit reactions for the construction of a new C-C bond and two C-N bonds are simple and efficient under mild conditions, and the yield of the target product is as high as 91%.