文献类型：期刊文献

中文题名：国内外氨基酸技术指标对比及分析方法研究进展

英文题名：Research Progress of Comparison of Technique Index at Home and Abroad and Determination Methods of Amino Acids

作者：顾小焱[1];郑琦[1];陈浩云[1];赵红莉[2];周丽芳[2]

机构：[1]国药集团化学试剂有限公司,上海200002;[2]华东理工大学化学与分子工程学院,上海200237

年份：2019

卷号：41

期号：1

起止页码：39

中文期刊名：化学试剂

外文期刊名：Chemical Reagents

收录：CSTPCD;;北大核心:【北大核心2017】；

基金：国家科技支撑项目(2015BAK44B00)

语种：中文

中文关键词：氨基酸;技术指标;分离纯化;分析方法

外文关键词：amino acids;technique index;separation and purification;determination methods

摘要：氨基酸是一切生命的物质基础,氨基酸的制备、分离纯化及分析检测等技术对生命科学和医药等的研究发展具有重要意义。随着上述研究及产业领域的快速发展,对高纯度氨基酸的需求也日益增加。发展高效的氨基酸分离纯化方法,建立不同纯度氨基酸的技术指标及标准分析方法,是规范行业发展、提升产品质量的关键。以L-谷氨酸为例,对比了国内外类似纯度产品的技术指标和分析方法。进一步综述了现阶段氨基酸的分离纯化及分析方法的发展概况。
Amino acids are the physical basis of life.The preparation,separation and purification and determination of amino acids are of great significance for the development of life science and medicine.With the rapid development of related fields,the demand for high-purity amino acids is also increasing.The key to standardize industry development and enhance products quality is the development of efficient methods for the separation and purification,and the establishment of technique index and standard determination methods for amino acids with different purity.L-Glutamic acid was taken as an example to compare the technique index and determination methods of the similar purity amino acids at home and abroad.Then,we reviewed the current methods for the separation and purification and determination of amino acids.