文献类型：期刊文献

英文题名：Spectrometric study on the binding of curcumin with AOT: Effect of micelle-to-vesicle transition

作者：Zhou, Haibo[1];Yang, Qianqian[1];Wang, Xiaoyong[1]

机构：[1]E China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China

年份：2014

卷号：161

起止页码：136

外文期刊名：FOOD CHEMISTRY

收录：;EI(收录号：20141817683726);WOS:【SCI-EXPANDED(收录号:WOS:000336872400018)】；

基金：This work is sponsored by the National Natural Science Foundation of China (Grant 21173081), the Natural Science Foundation of Shanghai (Grant 11ZR1408600), and the Fundamental Research Funds for the Central Universities (Grant WK1213003).

语种：英文

外文关键词：Vesicle; Curcumin; Absorption; Fluorescence; Binding constant

摘要：In this work, the role of micelle-to-vesicle transition of sodium bis(2-ethylhexyl) sulfosuccinate (AOT) in the binding, stability and antioxidant activity of curcumin has been studied using absorption and fluorescence measurements. As AOT molecules aggregate into micelles and vesicles, curcumin bound with AOT often gives higher intensities of absorption and fluorescence than that of free curcumin. The most enhanced absorption and fluorescence of curcumin induced by AOT vesicles, are attributed to the location of curcumin in their lipid bilayer. The measurement of curcumin anisotropy suggests that the bilayer of AOT vesicles provides curcumin with a more hydrophobic microenvironment than the palisade layer of AOT micelles. The binding constant (K-b) of curcumin with AOT vesicles is three times that of curcumin with AOT micelles. Moreover, AOT vesicles are found to be superior to AOT micelles for enhancing the stability and radical scavenging ability of curcumin. (C) 2014 Elsevier Ltd. All rights reserved.