文献类型：期刊文献

英文题名：Extraction of 20(S)-ginsenoside Rg2 from cultured Panax notoginseng cells in vitro stimulates human umbilical cord vein endothelial cell proliferation.

作者：Xin, Xiujuan[1];Liu, Jianwen;Li, Xiqiang;Zhong, Jianjiang;Wei, Dongzhi

机构：[1]State Key laboratory of Bioreactor Engineering, Institute of Biochemistry, East China University of Science and Technology, Shanghai, P.R. China.

年份：0

卷号：13

期号：3

外文期刊名：American journal of therapeutics

收录：MEDLINE(收录号：16772761);;PubMed

语种：英文

摘要：From the cultured cells of Panax notoginseng, a kind of ginseng saponin-ginsenoside Rg2, was separated and purified, and its structure was elucidated as 6-O-[alpha-L-rhamnose (l-->2)-beta-D-glucopyranosyl]3beta, 12beta, 20(S)-trihydroxydammar-24-ene [20(S)-ginsenoside Rg2]. Moreover, its bioactivity stimulates human umbilical cord vein endothelial cell proliferation; the growth of the cells treated with 20(S)-ginsenoside Rg2 was 14-fold higher than that of untreated ones, and the level of the cell's plasminogen activator (PA) was also twofold higher.