文献类型：期刊文献

中文题名：Gemini表面活性剂与DNA在气/液界面上的相互作用

英文题名：Interaction between Gemini and DNA at the Air/Water Interface

作者：康雪丽[1];陈启斌[1];尚亚卓[1];刘洪来[1]

机构：[1]华东理工大学,结构可控先进功能材料及其制备教育部重点实验室,上海200237

年份：2011

卷号：27

期号：6

起止页码：1467

中文期刊名：物理化学学报

外文期刊名：Acta Physico-Chimica Sinica

收录：CSTPCD;;Scopus;WOS:【SCI-EXPANDED(收录号:WOS:000291099500026)】；北大核心:【北大核心2008】；CSCD:【CSCD2011_2012】；

基金：The project was supported by the National Natural Science Foundation of China (20806025, 20706013), Creative Team Development Project of Ministry of Education of China (IRT0721), Scientific Research Foundation for the Returned Overseas Chinese Scholars, State Education Ministry and Fundamental Research Funds for the Central Universities, China.

语种：中文

中文关键词：Gemini表面活性剂;脱氧核糖核酸;π-A等温线;原子力显微镜;石英晶体微天平

外文关键词：Gemini surfactant; Deoxyribonucleic acid; π-A isotherm; Atomic force microscope; Quartz crystal microbalance

摘要：在气/液界面上,阳离子表面活性剂可以通过静电作用与阴离子型的脱氧核糖核酸(DNA)分子形成复合膜,并压缩沉积得到LB(Langmuir-Blodget)膜.利用表面压-表面积(π-A)曲线、原子力显微镜(AFM)和石英晶体18-微s-天18平,s=(Q3,C4M,6),研8,究10了,1阳2)离与子DNGAe(m双in链i表DN面A(活ds性DN剂A()[,C单18H链37D(CNHA3)(2sNsD+-N(CAH))2之)s-N间+的(C相H3互)2C作18用H3,7]·并2对Br1-8,-简s-1写8为在不同下相表面的分子面积进行了比较.实验结果表明连接基团和下相的DNA对Gemini表面活性剂在气/液界面上的性质有很大影响.此外,Gemini表面活性剂在界面上对DNA的吸附能力与它们之间的相互作用方式密切相关.
Monolayers may be obtained by an electrostatic force between cationic surfactants and anionic electrolyte deoxyribonucleic acid （DNA） molecules, and a corresponding Langmuir-Blodgett （LB） complex monolayer can be fabricated by compression and deposition of the monolayer at the air/water interface. In this work, the interaction between cationic Gemini surfactants （[C18H37（CH3）2N＋-（CH2）s-N＋（CH3）2- C18H37]·2Br-, abbreviated 18-s-18, s=3, 4, 6, 8, 10, 12） and double-strand DNA （dsDNA）/single-strand DNA （ssDNA） was investigated by surface pressure-surface area （π-A） isotherms, atomic force microscope （AFM）, and Quartz crystal microbalance （QCM）. Moreover, the limiting molecular areas of 18-s-18 on different subphases were compared. We found that the spacer and the subphase greatly influence the properties of the Gemini surfactants at the air/water interface. In addition, we conclude that the adsorption capacity of the Gemini surfactants with DNA is closely related to their interaction modes.