文献类型：期刊文献

英文题名：A New Antifungal Cyclic Lipopeptide from Bacillus marinus B-9987

作者：Liu, Rong-Feng[1];Zhang, Dao-Jing[1];Li, Yuan-Guang[1];Tao, Li-Ming[2];Tian, Li[3]

机构：[1]E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Pharmaceut Coll, Shanghai 200237, Peoples R China;[3]State Ocean Adm, Inst Oceanog 1, Qingdao 266061, Peoples R China

年份：2010

卷号：93

期号：12

起止页码：2419

外文期刊名：HELVETICA CHIMICA ACTA

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000285397600009)】；

基金：This work was financially supported by the High-Tech Program (863 Program) of China (2007AA091507 and 2008AA09Z435).

语种：英文

摘要：A new cyclic lipopeptide, marihysin A (1), along with the three known cyclodipeptides cyclo(Ala-Ile) (2), cyclo(Ala-Leu) (3), and cyclo(Ala-Tyr) (4), was isolated from the fermentation broth of the marine microorganism Bacillus marinus B-9987 isolated from the tissues of rhizophere of Suaeda salsa in the intertidal zone of the Bohai Bay of P. R. China. Marihysin A (1) was established to be cyclo(Pro-Gln-Asn(1)-Ser-Asn(2)-Tyr-Asn(3)-beta-aminotetradecanoic acid) by spectroscopic analysis, and it exhibits broad-spectrum but low activity against plant pathogens as determined by antifungal bioassay.