文献类型：期刊文献

英文题名：A redox-mediated chromogenic reaction and application in immunoassay

作者：Yu, Ru-Jia[1]; Ma, Wei[1]; Peng, Mao-Pan[1]; Bai, Zhi-Shan[2]; Long, Yi-Tao[1]

机构：[1] Key Laboratory for Advanced Materials, School of Chemistry & Molecular Engineering, East China University of Science and Technology, Shanghai, 200237, China; [2] State Environmental Protection Key Laboratory of Environmental Risk Assessment and Control on Chemical Process, East China University of Science and Technology, Shanghai, 200237, China

年份：2016

卷号：934

起止页码：226

外文期刊名：Analytica Chimica Acta

收录：EI(收录号：20164102891593)

语种：英文

外文关键词：Gold compounds - Oxidation - Colorimetry - Color - Gold nanoparticles - Chlorine compounds - Immunology

摘要：A novel redox-mediated chromogenic reaction was demonstrated based on the reaction between HAuCl4 and 2,2-azino-bis(3-ethylbenzothiazoline-6-sulfonic acid) (ABTS), which generate various color responses from red to green in the resulting solutions. Various redox substance could be used to mediate the reaction and trigger a distinct color response. We established a sensitive hydrogen peroxide colorimetric sensor based on the redox-mediated chromogenic reaction and depicted the application both in detection of enzyme and in an immunoassay. Combining the traditional chromogenic reagent with gold nanoparticles, our assay has the advantage in short response time (within three minutes), high sensitivity (10?12gmL?1 for HBsAg) and stability. ? 2016