文献类型：期刊文献

英文题名：Copper-Catalyzed Three-Component Reactions of α-Ketoaldehyde, 1,3-Dicarbonyl Compound, and Organic Boronic Acid in Water: A Route to 1,4-Diketones

作者：Xia, Qi[1];Li, Xiang[1];Fu, Xi[1];Zhou, Yaxuan[1];Peng, Yanqing[1];Wang, Jiayi[1];Song, Gonghua[1]

机构：[1]East China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2021

卷号：86

期号：14

起止页码：9914

外文期刊名：JOURNAL OF ORGANIC CHEMISTRY

收录：;EI(收录号：20212910656027);WOS:【SCI-EXPANDED(收录号:WOS:000674931400058)，CCR-EXPANDED(收录号:WOS:000674931400058)】；

基金：Financial support for this study from the National Key Research and Development Plan (grant no. 2017YFD0200504) is gratefully acknowledged.

语种：英文

外文关键词：Catalysis - Copper

摘要：A novel three-component reaction of alpha-ketoaldehydes, 1,3-dicarbonyl compounds, and organic boronic acids catalyzed by CuO in water has been developed to give a wide range of products containing 1,3/1,4-diketones. The method has some advantages such as the use of readily available starting materials, wide substrate scopes, excellent yields, gram-scale synthesis, and mild reaction conditions.