文献类型：期刊文献

英文题名：Controlling covalent functionalization of graphene oxide membranes to improve enantioseparation performances

作者：Meng, Chenchen[1,2];Chen, Qibin[1,2];Li, Xiaoxiao[1,2];Liu, Honglai[1,2]

机构：[1]East China Univ Sci & Technol, State Key Lab Chem Engn, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China

年份：2019

卷号：582

起止页码：83

外文期刊名：JOURNAL OF MEMBRANE SCIENCE

收录：;EI(收录号：20191506747829);WOS:【SCI-EXPANDED(收录号:WOS:000467250200009)】；

基金：We acknowledge the National Natural Science Foundation of China (No. 21576079, 91334203), the 111 Project of Ministry of Education of China (No. B08021), and the Fundamental Research Funds for the Central Universities of China for financial support.

语种：英文

外文关键词：Enantioseparations; Graphene oxide membranes; Ionic liquid; Controlled covalent functionalization; Chiral recognition

摘要：At present, the separation of racemates is still a great challenge due to their similarity in chemical structures and physicochemical properties. Here, we proposed a new strategy to improve the enantioseparation performances of graphene oxide (GO) based membranes via controlling the degree of functionalization (DF) of GO by the aid of an epoxide ring-opening reaction with a carboxyl-terminated ionic liquid (IL-COOH) as a spacer, followed by an amidation reaction of the l-glutamic acid (GO-IL-Glu) as chiral selectors. Results show that: i) these membranes are superior in the enantioselectivity and 1-3 orders of magnitude higher in the flux than traditional chiral separation membranes; ii) compared with l-glutamic acid modified GO membranes and their complex membranes with polypeptides in our previous work, they afford a ca. 40-80% increase in enantioselectivities and an order of magnitude increase in fluxes. Herein, IL-COOH groups can not only serve as a spacer, which is propitious to expanding the interlayer spacing of GO-IL-Glu nanosheets, thereby achieving high throughput of enantiomers, but also function as an active site to improve the grafting amount of chiral selectors (l-Glu), helpful for enhancing enantioselectivities. In particular, the flux is not compromised by the improved enantioselectivity in such membranes; on the contrary, it has an order of magnitude increase. Our findings suggest that the strategy used in this work, i.e., combining more chiral selectors with a wider interlayer spacing, could provide new opportunities for simultaneously facilitating high-flux and high-selectivity and a potential application in a great many enantio-and bio-separations.