文献类型：期刊文献

英文题名：Deciphering the adaptive conformational evolution of dihydrophenazine derivatives in the confined space of a semi-rigid macrocyclic host

作者：Liu, Hao[1];Jin, Xin[1];Mu, Shunxing[1];Wenyuan, Su[2];Zhang, Zhiyun[1];Su, Jianhua[1];Mei, Ju[1]

机构：[1]East China Univ Sci & Technol, Inst Fine Chem, Feringa Nobel Prize Scientist Joint Res Ctr, Frontiers Sci Ctr Materiobiol & Dynam Chem,Key Lab, 130 Meilong Rd, Shanghai 200237, Peoples R China;[2]Shanghai United Int Sch, 509 Pingji Rd,Wanyuan Campus, Shanghai 201102, Peoples R China

年份：2024

卷号：148

外文期刊名：OPTICAL MATERIALS

收录：;EI(收录号：20240215351512);WOS:【SCI-EXPANDED(收录号:WOS:001155092000001)】；

基金：We are grateful to the financial support from the National Natural Science Foundation of China (22275055, 21875064) , Shanghai Science and Technology Commission Basic Project Shanghai Natural Science Foundation (21ZR1417600) and the Fundamental Research Funds for the Central Universities. The authors thank the support of Research Center of Analysis and Test of East China University of Science and Technology for the help on the characterization.

语种：英文

外文关键词：Conformational evolution; Confined space; Macrocycles; N,N'-Disubstituted-dihydrophenazine; Host-guest systems

摘要：Exploring the conformational evolution of organic molecules is a long-pursuit theme in the field of chemistry. Herein, interests are endeavored to unveil the conformational evolution of conformationally flexible dihydrophenazines with environment-sensitive and continuously-changeable fluorescence in the confined space exerted by the semi-rigid macrocyclic host ExBox(4+). Co-crystals of the ExBox(4+) and dihydrophenazines are obtained via vapor diffusion, facilitating direct clarification of the structural variations of the host and guests. The adaptive ground-state conformational evolution of the guests is fully deciphered via H-1 NMR titration, crystallography analysis as well as systematic theoretical calculations. In contrast to the much smaller structural change of the well-noted conformationally adaptive host, the conformational variation in the central dihedral angle of the guest can be up to 22 in the crystal of the host-guest complex, which is completely different from the cases when ExBox(4+) interacting with the rigid guests. Dynamic information encryption has been further achieved by harnessing the distinct fluorescence behaviors before and after host-guest complexation. This work not only provides new insights into the understanding of mutual interactions between a semi-rigid host and conformationally flexible guests, but also offers an alternative scheme for advanced information encryption based on the luminescent host-guest complexes.