文献类型：期刊文献

英文题名：Application of β-Cyclodextrin metal-organic framework/titanium dioxide hybrid nanocomposite as dispersive solid-phase extraction adsorbent to organochlorine pesticide residues in honey samples

作者：Sun, Xuezhi[1];Fu, Zhibo[1];Jiang, Tianyu[1];Ning, Fanghong[2];Cheng, Yongzhe[1];Fu, Tianhao[1];Zhu, Mingsheng[1];Zhang, Hongyang[1];Zhang, Min[3];Hu, Ping[1]

机构：[1]East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China;[2]East China Univ Sci & Technol, Sch Biotechnol, Shanghai 200237, Peoples R China;[3]East China Univ Sci & Technol, Sch Pharm, China Shanghai Key Lab New Drug Design, Shanghai 200237, Peoples R China

年份：2022

卷号：1663

外文期刊名：JOURNAL OF CHROMATOGRAPHY A

收录：;EI(收录号：20215111371128);WOS:【SCI-EXPANDED(收录号:WOS:000735787200007)】；

基金：This research was funded by the National Natural Science Foun-dation of China (Grant number 81973285) .

语种：英文

外文关键词：Metal-organic framework; Organochlorine pesticide; D -SPE; GC-MS; MS; Honey

摘要：A simple and efficient dispersive solid-phase extraction (D-SPE) method combined with gas chromatography tandem mass spectrometry (GC-MS/MS) was developed to determine organochlorine pesticides (OCP) in honey. Firstly, a type of hybrid nanocomposite (CD-MOF/TiO 2 ) was prepared by grafting a metalorganic framework material synthesized with cyclodextrin as an organic ligand onto titanium dioxide. Then, the CD-MOF/TiO 2 was used as a D-SPE adsorbent to extract the OCP, and the effects of the amount of adsorbent, ultrasonic time, vortex time, pH, and salinity on the extraction were investigated using Plackett-Burman design and Box-Behnken Design. Under the optimized adsorption and desorption conditions, an analysis method that combined D-SPE with GC-MS/MS was established. The linear ranges of 14 OCP are 1-500 mu g kg -1 and the correlation coefficients are between 0.9991 and 1.0 0 0. The limits of detection and quantification vary from 0.01 to 0.04 mu g kg -1 and 0.04 to 0.12 mu g kg -1 , respectively. The intra-day and inter-day precision of this method are suitable (RSDs% less than 11.3%). The established CD-MOF/TiO 2 / D-SPE method was used for the extraction of OCP in honey samples with recovery in the range of 76.4 to 114.3%. The results demonstrate that the CD-MOF/TiO 2 has a good selective enrichment ability for OCP and is suitable for the D-SPE pretreat of honey sample analysis. (c) 2021 Elsevier B.V. All rights reserved.