文献类型：期刊文献

英文题名：Synthesis of trifluoromethylated compounds from alcohols via alkoxydiphenylphosphines

作者：Li, Jun-Li[1];Yang, Xian-Jin[1,2,3];Wang, Yanan[1];Liu, Jin-Tao[1]

机构：[1]Chinese Acad Sci, Shanghai Inst Organ Chem, Key Lab Organofluorine Chem, Shanghai 200032, Peoples R China;[2]E China Univ Sci & Technol, Adv Mat Lab, Shanghai 200237, Peoples R China;[3]E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China

年份：2015

卷号：178

起止页码：254

外文期刊名：JOURNAL OF FLUORINE CHEMISTRY

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000362929600036)】；

基金：The authors thank the National Natural Science Foundation of China for financial support (Nos. 21172243 and 21421002).

语种：英文

外文关键词：Trifluoromethylation; Alcohol; Alkyloxydiphenylphosphine; Methyl fluorosulfonyldifluoroacetate; Hydroxyl group

摘要：The transformation of hydroxyl group in benzyl or allyl alcohols to trifluoromethyl was achieved via the reaction of the corresponding alkyloxydiphenylphosphine and CuCF3, generated in situ from methyl fluorosulfonyldifluoroacetate and CuI, under mild conditions. A plausible mechanism was proposed on the basis of experimental results. (C) 2015 Elsevier B.V. All rights reserved.