文献类型：期刊文献

英文题名：Morphology Transformation of Hybrid Micelles Self-Assembled from Rod-Coil Block Copolymer and Nanoparticles

作者：Cai, Chunhua[1];Wang, Liquan[1];Lin, Jiaping[1];Zhang, Xu[1]

机构：[1]E China Univ Sci & Technol, Sch Mat Sci & Engn, Shanghai Key Lab Adv Polymer Mat,Minist Educ, State Key Lab Bioreactor Engn,Key Lab Ultrafine M, Shanghai 200237, Peoples R China

年份：2012

卷号：28

期号：9

起止页码：4515

外文期刊名：LANGMUIR

收录：;EI(收录号：20121114848720);WOS:【SCI-EXPANDED(收录号:WOS:000301038000057)】；

基金：This work was supported by National Natural Science Foundation of China (50925308), Program for Changjiang Scholars and Innovative Research Team in University (No. IR T0825), and National Basic Research Program of China (No. 2012CB933600). Support from projects of Shanghai municipality (10GG15, 08DZ2230500 and B502) is also appreciated.

语种：英文

外文关键词：Dissipative particle dynamics - Aggregates - Block copolymers - Gold nanoparticles - Polyethylene oxides - Light scattering - Polyethylene glycols - High resolution transmission electron microscopy - Morphology - Self assembly - Scanning electron microscopy

摘要：Hybrid polymeric micelles self-assembled from a mixture containing poly(gamma-benzyl-L-glutamate)-block-poly(ethylene glycol) (PBLG-b-PEG) block copolymer and gold nanoparticles (AuNPs) were prepared. The effect of AuNPs on the self-assembly behavior of PBLG-b-PEG was studied both experimentally by transmission electron microscopy, scanning electron microscopy, and laser light scattering and computationally using dissipative particle dynamics (DPD) simulations. It was found that, the pure PBLG-b-PEG block copolymer self-assembles into long cylindrical micelles. By introducing AuNPs to the stock block copolymer solution, the formed aggregate morphology transforms to spherical micelles. The DPD simulation results well reproduced the morphological transformations observed in the experiments. And the simulation revealed that the main reason for the aggregate morphology transformation is the breakage of ordered packing of PBLG rods in micelle core by the added nanoparticles. Moreover, from the DPD simulations, the distribution information on nanoparticles was obtained. The nanoparticles were found to prefer to locate near the core/shell interface as well as in the core center of the micelles. The combination of experimental and simulation methods lead to a comprehensive understanding of such a complex self-assembly system.