文献类型：期刊文献

英文题名：One-Pot Synthesis of Functionalized 2,5-Dihydrofurans via an Amine-Promoted Petasis Borono-Mannich Reaction

作者：Cui, Chun-Xiao[1,2];Li, Hui[3];Yang, Xian-Jin[1,2];Yang, Jun[3];Li, Xiao-Qiang[3]

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Inst Fine Chem, Shanghai 200237, Peoples R China;[3]Chinese Acad Sci, Shanghai Inst Organ Chem, Shanghai 200032, Peoples R China

年份：2013

卷号：15

期号：23

起止页码：5944

外文期刊名：ORGANIC LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000328231500010)，CCR-EXPANDED(收录号:WOS:000328231500010)】；

基金：We are grateful to the Chinese Academy of Science, Chinese Natural Science Foundation (Nos. 21372077, 20802088, 91017006, 90917017), for their financial supports.

语种：英文

摘要：A series of functionalized 2,5-dihydrofurans were efficiently synthesized via an amine-promoted Petasis borono-Mannich reaction of 4-substituted 1,2-oxaborol-2(5H)-ols with salicylaldehydes in high yields. The process, which combines a boronic acid-based Mannich reaction and a highly efficient intramolecular S(N)2 cyclization, provides a one-step and efficient route toward 2,5-dihydrofurans from simple and stable starting materials.