文献类型：期刊文献

英文题名：In situ monitoring of palladacycle-mediated carbonylation by surface-enhanced Raman spectroscopy

作者：Hu, Kai;Li, Da-Wei[1];Cui, Jing;Cao, Yue;Long, Yi-Tao

机构：[1]E China Univ Sci & Technol, Key Lab Adv Mat, Shanghai 200237, Peoples R China; E China Univ Sci & Technol, Dept Chem, Shanghai 200237, Peoples R China

年份：2015

卷号：5

期号：118

起止页码：97734

外文期刊名：RSC ADVANCES

收录：;EI(收录号：20154801611315);WOS:【SCI-EXPANDED(收录号:WOS:000365220100078)】；

基金：This research was supported by the National Natural Science Foundation of China (21421004, 21575041, 21327807), the Shanghai Pujiang Program Grant of China (12JC1403500), the Program of Shanghai Subject Chief Scientist (15XD1501200), and the Shanghai Municipal Natural Science Foundation (14ZR1410800, 14ZR1409400).

语种：英文

外文关键词：Carbon monoxide - Fiber optic sensors - Reaction kinetics - Synthesis (chemical) - Light transmission - Raman spectroscopy - Gold nanoparticles

摘要：Palladium-catalyzed carbonylation has emerged as one of the most potential approaches for the synthesis of carbonyl-containing molecules, however, the understanding remains challenging in many reactions partly because of a lack of robust monitoring methods. Herein, we report a novel surface-enhanced Raman spectroscopy (SERS) based strategy for the in situ monitoring of palladacycle-mediated carbonylation. The nanoplatforms integrated with SERS activity and reaction mediability were constructed through assembling new synthesized palladacycles (PCs) on the surface of gold nanoparticles. It was shown that, when carbon monoxide (CO) was introduced to the nanoplatform-containing system as a C1 source, palladacycle-mediated carbonylation was initiated, and the SERS spectra of the nanoplatforms changed concomitantly. With this SERS spectrum variation, the reaction mechanism could be investigated facilely, and the corresponding reaction was found to follow a pseudo-first-order kinetics rate law based on the relationship between the relative ratiometric peak intensities of I-1319/I-1338 and the reaction time. Therefore, using the proposed SERS approach, the carbonylation process could be directly monitored in situ without tedious pretreatments.