文献类型：期刊文献

英文题名：Design, synthesis and insecticidal activity of spiro heterocycle containing neonicotinoid analogs

作者：Chen, Nan-Yang[1];Ren, Li-Ping[1];Zou, Min-Ming[1];Xu, Zhi-Ping[1];Shao, Xu-Sheng[1];Xu, Xiao-Yong[1];Li, Zhong[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2014

卷号：25

期号：2

起止页码：197

外文期刊名：CHINESE CHEMICAL LETTERS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000331857500002)】；

基金：This work was financial supported by National Basic Research Program of China (973 Program, No. 2010CB126100), National High Technology Research Development Program of China (863 Program, No. 2011AA10A207), Key Projects in the National Science & Technology Pillar Program (No. 2011BAE06B05), National Natural Science Foundation of China (No. 21372079), Shanghai Education Committee (No. 12ZZ057) and the Fundamental Research Funds for the Central Universities. This work was also partly supported by Australia DC Foundation.

语种：英文

外文关键词：Neonicotinoid; Spiro heterocycle; Activity; Insecticide

摘要：Spiro heterocycles frequently occur in bioactive molecules. In the pursuit of neonicotinoids with Spiro heterocycles, three types of novel neonicotinoids with spirobenzofuranone, spirooxindole or spiroacenaphythylenone framework were designed and synthesized. Insecticidal evaluation showed that some of spirobenzofuranone containing neonicotinoids exhibited moderate activity against cowpea aphid, armyworm or brown planthopper. (C) 2013 Xu-Sheng Shao and Zhong Li. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.