文献类型：期刊文献

英文题名：The Association Between Childhood Adversity and Cognitive Aging Trajectory in Later Life: Evidence from the China Health and Retirement Longitudinal Study (CHARLS)

作者：Wang, Hua[1];Song, Xiagang[1,2];Wang, Zichuan[1];Hu, Kai[1]

机构：[1]East China Univ Sci & Technol, Sch Social & Publ Adm, 130 Meilong Rd, Shanghai, Peoples R China;[2]Shihezi Univ, Sch Law, Shihezi, Xinjiang, Peoples R China

年份：2026

外文期刊名：CLINICAL GERONTOLOGIST

收录：;WOS:【SSCI(收录号:WOS:001671853000001)，SCI-EXPANDED(收录号:WOS:001671853000001)】；

基金：This work was supported by the Youth Innovation Talent Training Programme of Shihezi University [CXPY202303] and Shanghai Pujiang Programme [23PJC022].

语种：英文

外文关键词：Childhood adversity; cognitive aging trajectory; depression symptoms; group-based trajectory model; mediation effect

摘要：ObjectivesThis study examined the association between childhood adversity and cognitive aging trajectories among Chinese older adults, exploring the mediating role of depressive symptoms.MethodsUsing five waves of the China Health and Retirement Longitudinal Study (CHARLS 2011-2020), we applied the group-based trajectory model, multinomial logistic regression and mediation analysis.ResultsCognitive aging trajectories in older Chinese adults were classified into three patterns: high baseline with slow decline (HBSD), medium baseline with moderate decline (MBMD), and low baseline with rapid decline (LBRD). Childhood adversity increased the likelihood of being in the LBRD (OR: 1.21, 95% CI: 1.15-1.27) and MBMD (OR: 1.11, 95% CI: 1.06-1.15) compared with HBSD, and in the LBRD relative to MBMD (OR: 1.09, 95% CI: 1.05-1.15). Depressive symptoms significantly mediated the associations between childhood adversity and cognitive aging trajectories.ConclusionsChildhood adversity has a direct effect and an indirect effect on cognitive aging trajectories through the depressive symptoms. Addressing depressive symptoms may help mitigate the long-term negative impact of early-life adversity on cognitive aging in older adults.Clinical ImplicationsTargeting depressive symptoms may be a key intervention point for promoting healthy cognitive aging in older adults who experienced childhood adversity.