文献类型：期刊文献

英文题名：Hydrogel formation via conjugated polymer-polyvinyl alcohol complexation for protein encapsulation

作者：Dai, Jingbo[1]; Liu, Zhubin[1]; Tian, Donglai[1]; Deng, Yanchen[1]; Hu, Aiguo[1]

机构：[1] School of Materials Science and Engineering, East China University of Science and Technology, Shanghai, 200237, China

年份：2026

卷号：83

期号：1

外文期刊名：Polymer Bulletin

收录：EI(收录号：20254919637669)

语种：英文

外文关键词：Catalyst activity - Complexation - Enzyme immobilization - Methyl ester

摘要：Linear conjugated polymers (LCPs) typically suffer from poor processability due to their rigid backbones, strong π–π stacking interactions, and broad molecular weight distributions, which impede the formation of stable three-dimensional networks and limit their bio-related applications. To overcome these limitations, we synthesized a narrowly dispersed boronic acid-functionalized linear conjugated polymer (BALCP) with terminal boronic acid groups via confined polymerization. This design enables directional assembly and network formation in aqueous systems through boronate ester bonding with polyvinyl alcohol (PVA). The resulting PVA-BALCP composite hydrogel demonstrates both high protein-loading capacity and efficient enzyme catalytic activity preservation, representing a promising platform for developing advanced enzyme immobilization systems and stimuli-responsive smart hydrogels. ? The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2025.