文献类型：期刊文献

英文题名：Toxicity assessment of zebrafish following exposure to CdTe QDs

作者：Zhang, Wei[1,2,3];Lin, Kuangfei[1,2,3];Miao, Youna[1,2,3];Dong, Qiaoxiang[4];Huang, Changjiang[4];Wang, Huili[4];Guo, Meijin[5];Cui, Xinhong[6]

机构：[1]E China Univ Sci & Technol, State Environm Protect Key Lab Environm Risk Asse, Shanghai 200237, Peoples R China;[2]E China Univ Sci & Technol, Shanghai Key Lab Funct Mat Chem, Shanghai 200237, Peoples R China;[3]E China Univ Sci & Technol, Sch Resource & Environm Engn, Shanghai 200237, Peoples R China;[4]Wenzhou Med Coll, Zhejiang Prov Key Lab Technol & Applicat Model Or, Wenzhou 325035, Peoples R China;[5]E China Univ Sci & Technol, State Key Lab Bioreactor Engn, Shanghai 200237, Peoples R China;[6]Shanghai Inst Landscape Gardening, Shanghai 200233, Peoples R China

年份：2012

卷号：213

起止页码：413

外文期刊名：JOURNAL OF HAZARDOUS MATERIALS

收录：;EI(收录号：20121214879051);WOS:【SCI-EXPANDED(收录号:WOS:000302893100052)】；

基金：This research was financially supported by the National Natural Science Foundation of China (40901148, 40871223), the Major State Basic Research Development Program of China (2011CB200904), the Scientific Project on Treatment and Control of Water Pollution (2012ZX07115), the National Environmental Protection Public Welfare Science and Technology Research Program of China (200909089), the National Forestry Public Welfare Science and Technology Research Program of China (201104088), the Fundamental Research Funds for the Central Universities (WB0911011), the Natural Science Foundation of Shanghai (11ZR1409400), and Zhejiang Provincial Science Foundation of China (Y5100333). We also would like to thank the anonymous referees for their helpful comments on this paper.

语种：英文

外文关键词：TGA-CdTe QDs; Zebrafish; Developmental toxicity; Behavioral toxicity

摘要：CdTe quantum dots (QDs) are nanocrystals of unique composition and properties that have found many new commercial applications; therefore, their potential toxicity to aquatic organisms has become a hot research topic. The lab study was performed to determine the developmental and behavioral toxicities to zebrafish under continuous exposure to low concentrations of CdTe QDs (1-400 nM) coated with thioglycolic acid (TGA). The results show: (1) the 120h LC50 of 185.9 nM, (2) the lower hatch rate and body length, more malformations, and less heart beat and swimming speed of the exposed zebrafish, (3) the brief burst and a higher basal swimming rate of the exposed zebrafish larvae during a rapid transition from light-to-dark, and (4) the vascular hyperplasia, vascular bifurcation, vascular crossing and turbulence of the exposed FLI-1 transgenic zebrafish larvae. (C) 2012 Elsevier B.V. All rights reserved.