文献类型：期刊文献

中文题名：Selective and sensitive fluorescence"turn-on"Zn^2+probes based on combination of anthracene,diphenylamine and dipyrrin

英文题名：Selective and sensitive fluorescence "turn-on" Zn^(2+) probes based on combination of anthracene,diphenylamine and dipyrrin

作者：Xiaodong Wei[1];Lulu Bu[1];Weiqiang Tang[2];Shuangliang Zhao[2];Yongshu Xie[1]

机构：[1]Key Laboratory for Advanced Materials and Institute of Fine Chemicals,School of Chem&try and Molecular Engineering,East China University of Science and Technology,Shanghai 200237,China;[2]State Key Laboratory of Chemical Engineering,School of Chemical Engineering,East China University of Science and Technology,Shanghai 200237,China

年份：2017

卷号：60

期号：9

起止页码：1212

中文期刊名：Science China Chemistry

外文期刊名：中国科学（化学英文版）

收录：Scopus;CSCD:【CSCD2017_2018】；PubMed;

基金：supported by the National Natural Science Foundation of China(21472047,91227201,91434110);the Program for Professor of Special Appointment(Eastern Scholar)at Shanghai Institutions of Higher Learning(GZ2016006);the Fundamental Research Funds for the Central Universities(WK1616004)

语种：英文

中文关键词：fluorescent;probes,;zinc;probes,;chelation;enhanced;fluorescence,;sensitivity

外文关键词：fluorescent probes; zinc probes; chelation enhanced fluorescence; sensitivity

摘要：Two fluorescence "turn-on" Zn^(2+) probes were developed by introducing an anthracenyl fluorophore through the linkage of a diphenylamino moiety at the 5-position of a dipyrrin moiety.Thus,two compounds with weak fluorescence were designed,synthesized,and employed as CHEF(chelation enhanced fluorescence) type fluorescence "turn-on" Zn^(2+) probes,which exhibit dramatic fluorescence enhancement upon addition of Zn^(2+),showing high sensitivities and impressive detection limits of 13 and12 nM,respectively,better than their analogues containing simple aryl substituents at the 5 positions of a di-or tripyrrin moiety.In addition,both of the probes exhibit good selectivity,short response time of less than 10 s and wide applicable pH ranges.Furthermore,the weak fluorescence nature of the probes was rationalized based on viscosity dependence measurements and theoretical calculations.These results provide further insight into the development of selective and sensitive zinc probes.
Two fluorescence 'turn-on' Zn2+ probes were developed by introducing an anthracenyl fluorophore through the linkage of a diphenylamino moiety at the 5-position of a dipyrrin moiety. Thus, two compounds with weak fluorescence were designed, synthesized, and employed as CHEF (chelation enhanced fluorescence) type fluorescence 'turn-on' Zn2+ probes, which exhibit dramatic fluorescence enhancement upon addition of Zn2+, showing high sensitivities and impressive detection limits of 13 and 12 nM, respectively, better than their analogues containing simple aryl substituents at the 5 positions of a di- or tripyrrin moiety. In addition, both of the probes exhibit good selectivity, short response time of less than 10 s and wide applicable pH ranges. Furthermore, the weak fluorescence nature of the probes was rationalized based on viscosity dependence measurements and theoretical calculations. These results provide further insight into the development of selective and sensitive zinc probes.