文献类型：期刊文献

英文题名：Ligand-Free Nickel-Catalysed 1,4-Addition of Arylboronic Acids to α,β-Unsaturated Carbonyl Compounds

作者：Chen, Wen[1];Sun, Lu[1];Huang, Xi[1];Wang, Jiayi[1];Peng, Yanqing[1];Song, Gonghua[1]

机构：[1]E China Univ Sci & Technol, Sch Pharm, Shanghai Key Lab Chem Biol, Shanghai 200237, Peoples R China

年份：2015

卷号：357

期号：7

起止页码：1474

外文期刊名：ADVANCED SYNTHESIS & CATALYSIS

收录：;WOS:【SCI-EXPANDED(收录号:WOS:000354253600016)，CCR-EXPANDED(收录号:WOS:000354253600016)】；

基金：Financial support for this study from the National Key Technology R&D Program (Grant No. 2011BAE06B05-4) is gratefully acknowledged.

语种：英文

外文关键词：1,4-addition; arylboronic acids; ligand-free conditions; nickel; alpha,beta-unsaturated carbonyl compounds

摘要：A simple and efficient ligand-free nickel-based catalytic system has been developed for the 1,4-addition of arylboronic acids to alpha,beta-unsaturated carbonyl compounds. With catalyst loadings of 12 mol%, a series of 1,4-adducts from chalcones and cinnamates was obtained in moderate to excellent yields within 5-30 min under a nitrogen atmosphere and microwave irradiation. The 1,4-addition of arylboronic acids to acrylates is less efficient.