文献类型：期刊文献

英文题名：An Open Tubular Ion Chromatograph

作者：Yang, Bingcheng[1,2];Zhang, Min[1];Kanyanee, Tinakorn[1,3];Stamos, Brian N.[1];Dasgupta, Purnendu K.[1]

机构：[1]Univ Texas Arlington, Dept Chem & Biochem, Arlington, TX 76019 USA;[2]E China Univ Sci & Technol, Sch Pharm, Shanghai 200237, Peoples R China;[3]Chiang Mai Univ, Dept Chem, Chiang Mai 50200, Thailand

年份：2014

卷号：86

期号：23

起止页码：11554

外文期刊名：ANALYTICAL CHEMISTRY

收录：;EI(收录号：20145000312385);WOS:【SCI-EXPANDED(收录号:WOS:000345803300016)】；

基金：This work was supported by NASA Grant NNX11AO66G. B.Y. acknowledges NSFC Grant 21322502; K.T. acknowledges support from IPST and IFS Grant W-5094-1. We thank Phillip Shelor for his assistance throughout this work.

语种：英文

外文关键词：Ions - Esters - Chromatography - Inorganic compounds - Ion exchange

摘要：We describe an open tubular ion chromatograph (OTIC) that uses anion exchange latex coated 5 mu m radius silica and 9.8 mu m radius poly(methyl methacrylate) tubes and automated time/pressure based hydrodynamic injection for pL-nL scale injections. It is routinely possible to generate 50?000 plates or more (up to 150 000 plates/m, columns between 0.3 and 0.8 m have been used), and as such, fast separations are possible, comparable to or in some cases better than the current practice of IC. With an optimized admittance detector, nonsuppressed detection permits LODs of submicromolar to double digit micromolar for a variety of analytes. However, large volume injections are possible and can significantly improve on this. A variety of eluents, the use of organic modifiers, and variations of eluent pH can be used to tailor a given separation. The approach is discussed in the context of extraterrestrial exploration, especially Mars, where the existence of large amounts of perchlorate in the soil needs to be confirmed. These columns can survive drying and freezing, and small footprint, low power consumption, and simplicity make OTIC a good candidate for such a mission.