文献类型：期刊文献

英文题名：Magnetic properties of Al3+doped Fe3O4 by solid-solid reaction and biological applications of GQDs grafted MNPs

作者：Huan, Weiwei[1];Dong, Mengyang[2];Li, Jie[2];Xie, Meng[3];Huang, Yan[2];Carlini, Riccardo[4];Yang, Yuxiang[2]

机构：[1]Zhejiang A&F Univ, Coll Chem & Mat Engn, Zhejiang Prov Key Lab Chem Utilizat Forestry Bioma, Hangzhou 311300, Zhejiang, Peoples R China;[2]East China Univ Sci & Technol, Sch Chem & Mol Engn, Shanghai 200237, Peoples R China;[3]Jiangsu Univ, Sch Pharm, Zhenjiang 212013, Jiangsu, Peoples R China;[4]LAS Klee Barabino, Chem & Mat Chem Dept, I-16146 Genoa, Italy

年份：2023

卷号：587

外文期刊名：JOURNAL OF MAGNETISM AND MAGNETIC MATERIALS

收录：;EI(收录号：20234114860560);WOS:【SCI-EXPANDED(收录号:WOS:001090964900001)】；

基金：We thank Frank Kitching, MSc., from Liwen Bianji (Edanz) ( www.liwenbianji.cn) for editing the English text of a draft of this manuscript. The present work was supported by the National Natural Science Foundation of China (grant numbers 20577010 and 20971043) , and by the Open Project Program of State Key Laboratory of Inorganic Synthesis and Preparative Chemistry, Jilin University.

语种：英文

外文关键词：Al3+-doped; Solid-solid reaction; Magnetic property; GQDs grafted

摘要：2.79 % Al3+ doped Fe3O4 magnetic nanoparticles (Al-Fe3O4 MNPs) was prepared by a solid-solid reaction between aluminum formic acid hydrazide and as-prepared Fe3O4 magnetic nanoparticles. The obtained Al-Fe3O4 MNPs were strongly ferromagnetic, and their greatest saturation magnetization value was 82.3 electromagnetic units per gram (emu/g). The Al-Fe3O4 MNPs were subsequently coated with SiO2. High-resolution transmission electron microscopy (HRTEM), X-ray powder diffraction (XRD), Mo center dot ssbauer spectroscopy, and vibrating-sample magnetometry (VSM) were used to characterize the morphology, structure, magnetic properties, and doping mechanism of the doped magnetic particles, respectively. Then graphene quantum dot (GQD) is loaded on the surface of aminated Al-Fe3O4@SiO2 (AFS) MNPs by a covalent connection, and Al-Fe3O4@SiO2-GQDs (AFSG) MNPs. Furthermore, AFSG MNPs were labeled with the metastable nuclear isomer of technetium-99 (99mTc) and their in vivo targeting performance was investigated. The AFSG-99mTc MNPs demonstrated a relatively strong magnetic response in a pulsed magnetic gradient field. The data obtained from the control and experimental groups indicated that the ability to uptake radioactivity of the livers of New Zealand rabbits via the magnetic targeted intervention was 3.69 times higher than that without the magnetic targeted intervention.