成果/Result
- Clodronate-loaded liposomal and fibroblast-derived exosomal hybrid system for enhanced drug delivery to pulmonary fibrosis被引量：157收藏
- 作者：Sun, Lingna Fan, Mingrui Huang, Dong Li, Bingqin Xu, Ruoting Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOMATERIALS 2021
- 关键词：Pulmonary fibrotic therapy Exosomes Liposomes Macrophages depletion Fibrosis penetration
- Vasodilator Hydralazine Promotes Nanoparticle Penetration in Advanced Desmoplastic Tumors被引量：88收藏
- 作者：Chen, Yanzuo Song, Wantong Shen, Limei Qiu, Nasha Hu, Mengying Liu, Yun Liu, Qi Huang, Leaf
- 机构：Univ N Carolina;Univ N Carolina;East China Univ Sci & Technol;Chinese Acad Sci;Zhejiang Univ
- 来源：ACS NANO 2019
- 关键词：hydralazine nanoparticles tumor penetration desmoplastic tumor tumor microenvironment
- Clodronate-nintedanib-loaded exosome-liposome hybridization enhances the liver fibrosis therapy by inhibiting Kupffer cell activity被引量：40收藏
- 作者：Ji, Keqin Fan, Mingrui Huang, Dong Sun, Lingna Li, Bingqin Xu, Ruoting Zhang, Jiajing Shao, Xuan Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOMATERIALS SCIENCE 2022
- 关键词：Antigen-antibody reactions - Cell culture - Controlled drug delivery - Liver - Macrophages - Targeted drug delivery
- Biological Hyperthermia-Inducing Nanoparticles for Specific Remodeling of the Extracellular Matrix Microenvironment Enhance Pro-Apoptotic Therapy in Fibrosis被引量：24收藏
- 作者：Zhang, Jinru Ji, Keqin Ning, Yuanmeng Sun, Lingna Fan, Mingrui Shu, Chunjie Zhang, Ziqi Tu, Tianyu Cao, Jingyun Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS NANO 2023
- 关键词：fibrosis exosome and liposome hybrid nanoparticles hyperthermia 2 4-dinitrophenol remodelingof the extracellular matrix microenvironment
- Tofacitinib Citrate Coordination-Based Dual-Responsive/Scavenge Nanoplatform Toward Regulate Colonic Inflammatory Microenvironment for Relieving Colitis被引量：16收藏
- 作者：Zou, Jiafeng Jiang, Kun Chen, You Ma, Ying Xia, Chuanhe Ding, Wenxing Yao, Min Lin, Yiting Chen, Yanzuo Zhao, Yuzheng Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Med Sci;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ADVANCED HEALTHCARE MATERIALS 2024
- 关键词：colitis colonic inflammatory microenvironment coordination nanoplatform dual-responsive dual-scavenge tofacitinib citrate
- An anti-miR-301a and zinc coordination driven nanozyme loaded in nanoparticle for oral therapy of inflammatory bowel disease based on colitis microenvironment regulation被引量：6收藏
- 作者：Zou, Jiafeng Xia, Chuanhe Yao, Min Pan, Xier Zheng, Shulei Lin, Yiting Zhao, Xinlin Wang, Yanwen Chen, Yanzuo Lan, Minbo Wang, Junshan Gao, Feng
- 机构：East China Univ Sci & Technol;Tongji Univ;Bengbu First Peoples Hosp;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHEMICAL ENGINEERING JOURNAL 2025
- 关键词：Coordination driven nanozyme Anti-miR-301a Zinc Colitis microenvironment regulation Inflammatory bowel disease Oral nanoparticle
- Rapamycin and Hyperoside-Co-loaded Macrophage Delivery System Enhanced Pulmonary Fibrosis Therapy by Autophagy Upregulation and Epithelial-to-Mesenchymal Transition Inhibition被引量：4收藏
- 作者：Wang, Qi Ning, Yuanmeng Zhang, Jinru Du, Xu Xu, Zihan Hu, Yongcheng Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2024
- 关键词：pulmonary fibrosis autophagy epithelial-to-mesenchymaltransition macrophage drug delivery system extracellulartraps
