成果/Result
- Development of a new colorimetric assay for lipoxygenase activity被引量：48收藏
- 作者：Lu, Weiqiang Zhao, Xue Xu, Zhongyu Dong, Ningning Zou, Shien Shen, Xu Huang, Jin
- 机构：E China Univ Sci & Technol;Fudan Univ
- 来源：ANALYTICAL BIOCHEMISTRY 2013
- 关键词：Lipoxygenase Colorimetric assay Ferrithiocyanate Lipid hydroperoxides Inhibitors
- FXR antagonism of NSAIDs contributes to drug-induced liver injury identified by systems pharmacology approach被引量：42收藏
- 作者：Lu, Weiqiang Cheng, Feixiong Jiang, Jing Zhang, Chen Deng, Xiaokang Xu, Zhongyu Zou, Shien Shen, Xu Tang, Yun Huang, Jin
- 机构：E China Normal Univ;E China Normal Univ;E China Univ Sci & Technol;Fudan Univ;Shanghai Inst Mat Med
- 来源：SCIENTIFIC REPORTS 2015
- Drug Repurposing of Histone Deacetylase Inhibitors That Alleviate Neutrophilic Inflammation in Acute Lung Injury and Idiopathic Pulmonary Fibrosis via Inhibiting Leukotriene A4 Hydrolase and Blocking LTB4 Biosynthesis被引量：33收藏
- 作者：Lu, Weiqiang Yao, Xue Ouyang, Ping Dong, Ningnin Wu, Dang Jiang, Xingwu Wu, Zengrui Zhang, Chen Xu, Zhongyu Tang, Yun Zou, Shien Liu, Mingyao Li, Jian Zeng, Minghua Lin, Ping Cheng, Feixiong Huang, Jin
- 机构：East China Univ Sci & Technol;East China Normal Univ;East China Normal Univ;Fudan Univ;Guangxi Normal Univ
- 来源：JOURNAL OF MEDICINAL CHEMISTRY 2017
- Dietary flavonoids fisetin and myricetin: Dual inhibitors of Plasmodium falciparum falcipain-2 and plasmepsin II被引量：29收藏
- 作者：Jin, Huangtao Xu, Zhongyu Cui, Kunqiang Zhang, Tianshu Lu, Weiqiang Huang, Jin
- 机构：E China Univ Sci & Technol;E China Normal Univ;E China Normal Univ
- 来源：FITOTERAPIA 2014
- 关键词：Dietary flavonoids Falcipain-2 Plasmepsin Il Dual inhibitor
- Stabilizing Effect of Soluplus on Erlotinib Metastable Crystal Form in Microparticles and Amorphous Solid Dispersions被引量：18收藏
- 作者：Jia, Shuyu Ning, Shangqi Leng, Yuting Jing, Qiufang Xu, Zhongyu Ren, Fuzheng
- 机构：East China Univ Sci & Technol
- 来源：POLYMERS 2022
- 关键词：erlotinib soluplus microparticles solid dispersions stabilization
- Construction of the Isocopalane Skeleton: Application of a Desulfinylative 1,7-Hydrogen Atom Transfer Strategy被引量：12收藏
- 作者：Xiao, Xiong Xu, ZhongYu Zeng, Qian-Ding Chen, Xi-Bo Ji, Wen-Hao Han, Ying Wu, PeiYing Ren, Jiangmeng Zeng, Bu-Bing
- 机构：E China Univ Sci & Technol;Chinese Acad Sci;Shanghai Univ Tradit Chinese Med;Yangzhou Univ
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2015
- 关键词：hydrogen transfer natural products persulfates synthons terpenoids
- Luciferase Reporter Gene Assay on Human 5-HT Receptor: Which Response Element Should Be Chosen?被引量：11收藏
- 作者：Chen, Yiming Xu, Zhongyu Wu, Dang Li, Jian Song, Cheng Lu, Weiqiang Huang, Jin
- 机构：E China Univ Sci & Technol;Nanchang Hangkong Univ;E China Normal Univ;E China Normal Univ
- 来源：SCIENTIFIC REPORTS 2015
- Modified rivaroxaban microparticles for solid state properties improvement based on drug-protein/polymer supramolecular interactions被引量：11收藏
- 作者：Chen, Ning Di, Peiwen Ning, Shangqi Jiang, Wenjun Jing, Qiufang Ren, Guobin Liu, Yan Tang, Yun Xu, Zhongyu Liu, Guixia Ren, Fuzheng
- 机构：East China Univ Sci & Technol
- 来源：POWDER TECHNOLOGY 2019
- 关键词：Bottom-up Dissolution Molecular docking Rivaroxaban Supramolecular interactions
- Corosolic acid-modified lipid nanoparticles as delivery carriers for DNA vaccines against avian influenza被引量：10收藏
- 作者：Guo, Ziyan Jing, Qiufang Xu, Zhongyu Zhang, Dahe Zheng, Wenyun Ren, Fuzheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Suzhou Womei Biol Co Ltd;East China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF PHARMACEUTICS 2023
- 关键词：Lipid nanoparticles Cholesterol Corosolic acid Avian influenza vaccine Immune responses
- An Efficient and Convenient Protocol for Highly Regioselective Cleavage of Terminal Epoxides to β-Halohydrins被引量：9收藏
- 作者：Wang, Tao Ji, Wen-Hao Xu, Zhong-Yu Zeng, Bu-Bing
- 机构：E China Univ Sci & Technol
- 来源：SYNLETT 2009
- 关键词：epoxide beta-halohydrin cleavage regioselectivity chemoselectivity
- Antiproliferative activity and therapeutic implications of potassium tris(4-methyl-1-pyrazolyl) borohydride in hepatocellular carcinoma被引量：5收藏
- 作者：Jin, Huangtao Xu, Zhongyu Li, Dongfeng Huang, Jin
- 机构：E China Univ Sci & Technol;Cent China Normal Univ
- 来源：CHEMICO-BIOLOGICAL INTERACTIONS 2014
- 关键词：Potassium tris-(4-methyl-1-pyrazolyl)-borohydride Hepatocellular carcinoma Iron chelator Reactive oxygen species
- An Enzyme Kinetics-Based Laboratory Module Aimed at Introducing Undergraduates to High-Throughput Drug Screening被引量：0收藏
- 作者：He, Xiangli Huang, Ying Xu, Zhongyu Liu, Xi Xu, Zhaomin Ma, Lei Zhao, Yuzheng Huang, Jin
- 机构：East China Univ Sci & Technol;Guangdong Inst Drug Control
- 来源：JOURNAL OF CHEMICAL EDUCATION 2023
- 关键词：Upper-Division Undergraduate Biochemistry Enzyme Kinetics High-Throughput Drug Screening Hands-On Learning Laboratory Education
- DHODH is a synthetic lethal target in PIK3CA-mutant colorectal cancer被引量：0收藏
- 作者：Liang, Jun Liu, Xi Ni, Ziyun Zhang, Sen He, Xiangli Wang, Lili Huang, Yukun Xu, Zhaomin Xu, Zhongyu Qian, Jiayi Lu, Lixue Abuduaini, Naijipu Tian, Jing Zeng, Minghua Wang, Qi Sun, Jing Xie, Qiong Wang, Yonghui Lu, Weiqiang Feng, Bo Han, Bo Huang, Jin
- 机构：East China Univ Sci Technol;Shanghai Jiao Tong Univ;Shanghai Jiao Tong Univ;Fudan Univ;Shihezi Univ
- 来源：CELL REPORTS 2026
- 关键词：cancer stemness colorectal cancer DHODH O-GlcNAcylation PIK3CA mutation
- A Course of Proteolytic Stability Experiment for Undergraduates: Drug Affinity Responsive Target Stability (DARTS)被引量：0收藏
- 作者：Huang, Jin Chen, Caiyue Xu, Zhaomin Xu, Zhongyu Sun, Zhongying Huang, Ying
- 机构：East China Univ Sci & Technol;Guangdong Inst Drug Control
- 来源：JOURNAL OF CHEMICAL EDUCATION 2025
- 关键词：Upper-Division Undergraduate Biochemistry Hands-On Learning/Manipulatives Electrophoresis DARTS Proteolytic stability Computational Tools
