成果/Result
- Design, synthesis and evaluation of diosgenin carbamate derivatives as multitarget anti-Alzheimer's disease agents被引量：44收藏
- 作者：Yang, Gui-Xiang Huang, Yan Zheng, Lu-Lu Zhang, Li Su, Lin Wu, Yu-Hang Li, Jie Zhou, Li-Cheng Huang, Jin Tang, Yun Wang, Rui Ma, Lei
- 机构：East China Univ Sci & Technol
- 来源：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2020
- 关键词：Alzheimer's disease Diosgenin Antioxidant Anti-inflammatory Anti-A beta activity Multi-target-directed ligands
- Design, synthesis and biological evaluation of novel osthole-based derivatives as potential neuroprotective agents被引量：9收藏
- 作者：Zhang, Li Wu, Yuhang Yang, Guixiang Gan, Haixian Sang, Dayong Zhou, Jiye Su, Lin Wang, Rui Ma, Lei
- 机构：East China Univ Sci & Technol;Jingchu Univ Technol
- 来源：BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2020
- 关键词：Osthole Neuroprotection Antioxidant Anti-inflammation Amyloid beta-protein Molecular docking
- One-electron reduction triggered nitric oxide release for ischemia-reperfusion protection被引量：8收藏
- 作者：Xu, Xiu Sun, Meiling Luo, Xiao Zhang, Ziqian Su, Lin Cui, Lingfei Zhu, Zhihui Lu, Xicun Wang, Rui Han, Feng Qian, Xuhong Yang, Youjun
- 机构：East China Univ Sci & Technol;Nanjing Med Univ;East China Normal Univ;Guangxi Univ Chinese Med;East China Univ Sci & Technol
- 来源：FREE RADICAL BIOLOGY AND MEDICINE 2021
- 关键词：Nitric oxide N-nitrosated dye Reduction-triggered release Fluorescence Ischemia-reperfusion protection
- Synthesis and biological evaluation of 3-carbamate smilagenin derivatives as potential neuroprotective agents被引量：6收藏
- 作者：Zhang, Cong Wu, Yan Li, Jie Yang, Gui-Xiang Su, Lin Huang, Yan Wang, Rui Ma, Lei
- 机构：East China Univ Sci & Technol
- 来源：BIOORGANIC & MEDICINAL CHEMISTRY LETTERS 2019
- 关键词：Smilagenin derivatives Alzheimer's disease Oxidative stress Neuroprotective activity
- Ivermectin induced early developmental damage to the nervous system of zebrafish larvae被引量：0收藏
- 作者：Jiang, Yixuan Su, Lin Peng, Bo Wang, Weiguo Zhang, Yang
- 机构：East China Univ Sci & Technol;United World Coll South East Asia Dover
- 来源：ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY 2025
- 关键词：Ivermectin Zebrafish Neurological development Safety evaluation
