成果/Result
- The yeast peroxisome: A dynamic storage depot and subcellular factory for squalene overproduction被引量：194收藏
- 作者：Liu, Guo-Song Li, Tian Zhou, Wei Jiang, Min Tao, Xin-Yi Liu, Min Zhao, Ming Ren, Yu-Hong Gao, Bei Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：METABOLIC ENGINEERING 2020
- 关键词：Synthetic biology Saccharomyces cerevisiae Peroxisome Storage depot Subcellular factory Terpene
- Metabolic compartmentalization in yeast mitochondria: Burden and solution for squalene overproduction被引量：115收藏
- 作者：Zhu, Zhan-Tao Du, Meng-Meng Gao, Bei Tao, Xin-Yi Zhao, Ming Ren, Yu-Hong Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：METABOLIC ENGINEERING 2021
- 关键词：Saccharomyces cerevisiae Mitochondrial engineering Metabolic burden Squalene Dual engineering
- Metabolic Engineering of Saccharomyces cerevisiae To Overproduce Squalene被引量：71收藏
- 作者：Li, Tian Liu, Guo-Song Zhou, Wei Jiang, Min Ren, Yu-Hong Tao, Xin-Yi Liu, Min Zhao, Ming Wang, Feng-Qing Gao, Bei Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2020
- 关键词：Saccharomyces cerevisiae metabolic engineering squalene overproduction ethanol carbon source utilization
- Multidimensional engineering of Saccharomyces cerevisiae for the efficient production of heme by exploring the cytotoxicity and tolerance of heme被引量：20收藏
- 作者：Guo, Qidi Li, Jiacun Wang, Ming-Rui Zhao, Ming Zhang, Gege Tang, Shuyan Xiong, Liang-Bin Gao, Bei Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：METABOLIC ENGINEERING 2024
- 关键词：Heme Saccharomyces cerevisiae Metabolic engineering Heme cytotoxicity Laboratory evolution
- De novo design of a transcription factor for a progesterone biosensor被引量：20收藏
- 作者：Liu, Kun Zhang, Yunsen Liu, Ke Zhao, Yunqiu Gao, Bei Tao, Xinyi Zhao, Ming Wang, Feng-Qing Wei, Dongzhi
- 机构：East China Univ Sci & Technol;Chengdu Univ Tradit Chinese Med
- 来源：BIOSENSORS & BIOELECTRONICS 2022
- 关键词：Artificial transcription factor Molecular dynamics simulation Progesterone biosensor Whole-cell Diagnosis
- Transformation of phytosterols into pregnatetraenedione by a combined microbial and chemical process被引量：18收藏
- 作者：Liu, Yong-Jun Ji, Wei-ting Song, Lu Tao, Xin-Yi Zhao, Ming Gao, Bei Meng, Hao Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol;Hunan Norchem Pharmaceut Co Ltd
- 来源：GREEN CHEMISTRY 2022
- 关键词：Alcohols - Carboxylation - Drug products - Metabolism - Metabolites - Polyols
- Structure-guided engineering of a flavin-containing monooxygenase for the efficient production of indirubin被引量：17收藏
- 作者：Sun, Bing-Yao Sui, Hua-Lu Liu, Zi-Wei Tao, Xin-Yi Gao, Bei Zhao, Ming Ma, Yu-Shu Zhao, Jian Liu, Min Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：BIORESOURCES AND BIOPROCESSING 2022
- 关键词：Flavin-containing monooxygenase Indirubin Loop region Substrate tunnel Structure-guided enzyme engineering Microbial synthesis
- A highly sensitive, selective ratiometric fluorescent probe for cobalt(II) and its applications for biological imaging被引量：15收藏
- 作者：Zhang, Shenyi Zhao, Mei Zhu, Weiping Xu, Yufang Qian, Xuhong
- 机构：E China Univ Sci & Technol
- 来源：DALTON TRANSACTIONS 2015
- 关键词：Charge transfer - Cobalt compounds - Fluorescence
- Engineering diverse eubacteria promoters for robust Gene expression in Streptomyces lividans被引量：14收藏
- 作者：Zhao, Ming Wang, Shui-Ling Tao, Xin-Yi Zhao, Guo-Ling Ren, Yu-Hong Wang, Feng-Qing Wei, Dong-Zhi
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2019
- 关键词：Streptomyces Heterologous promoter 5 '-UTR RBS sigma hrdB
- Engineering Mycolicibacterium neoaurum for the production of antioxidant ergothionEIne被引量：12收藏
- 作者：Xiong, Liang-Bin Xie, Zhi-Yong Ke, Jie Wang, Li Gao, Bei Tao, Xin-Yi Zhao, Ming Shen, Ya-Ling Wei, Dong-Zhi Wang, Feng-Qing
- 机构：East China Univ Sci & Technol;Shanghai Univ Med & Hlth Sci;Huawei Safety Evaluat & Med Res Shanghai Co Ltd
- 来源：FOOD BIOENGINEERING 2022
- 关键词：endogenous metabolic engineering ergothionEIne Mycolicibacterium neoaurum S-adenosyl-L-methionine regeneration
- 超滤法纯化超氧物岐化酶被引量：0收藏
- 作者：赵铭 袁勤生 朱树新
- 机构：华东化工学院生化工程研究所
- 来源：《华东化工学院学报》 1991
- 关键词：歧化酶 提纯 过滤膜
- 摘要：研制了适合纯化猪血超氧物岐化酶(Cu.Zn-SOD)溶液的醋酸纤维素(CA)超滤膜,其截留分子量约为16 000。研究了溶液浓度、操作压力等因素对通量的影响。结果表明,自制CA膜超滤纯化SOD溶液性能优于一些市售膜。收率...
- 下载全文在线阅读
