成果/Result
- Cloning of thermostable cellulase genes of Clostridium thermocellum and thEIr secretive expression in Bacillus subtilis被引量：24收藏
- 作者：Liu, Jian-Ming Xin, Xiu-Juan Li, Chun-Xiu Xu, Jian-He Bao, Jie
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Applied Biochemistry and Biotechnology 2012
- 关键词：Bacteriology - Clostridium - Strain - Cellulose - Gene expression
- 壳聚糖修饰L-天门冬酰胺酶对酶活及抗原的影响被引量：10收藏
- 作者：辛秀娟 魏东芝 董常松 周文瑜 刘建文
- 机构：华东理工大学生物反应器工程国家重点实验室
- 来源：《华东理工大学学报（自然科学版）》 2002
- 关键词：酶活 抗原 N,0-羧甲基壳聚糖 L-天门冬酰胺酶 化学修饰 癌细胞 免疫沉淀 生物药品
- 摘要：采用水溶性壳聚糖对 L-天门冬酰胺酶进行化学修饰 ,修饰后的酶活回收率高达 70 % ,修饰酶的比活为每毫克蛋白质 1 2 1 .79U,p H值为 7.4,更接近于人体血浆 p H值 (7.2～ 7.4) ,对底物的亲...
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- Substrate promiscuity of pyruvate kinase on various deoxynucleoside diphosphates for synthesis of deoxynucleoside triphosphates被引量：7收藏
- 作者：Gao, Shuhong Bao, Jie Gu, Xiaoming Xin, Xiujuan Chen, Changhua Ryu, Dewey D. Y.
- 机构：E China Univ Sci & Technol;Univ Calif Davis
- 来源：ENZYME AND MICROBIAL TECHNOLOGY 2008
- 关键词：Promiscuity Pyruvate kinase (PK) Deoxynucleoside triphosphate (dNTP) Bacillus sp PK Zymomonas mobilis PK
- Efficient ilamycins production utilizing Enteromorpha prolifera by metabolically engineered Streptomyces atratus被引量：5收藏
- 作者：Jiang, Yu-Xi Zheng, Gao-Fan Chen, Long-Chao Yang, Na Xin, Xiu-Juan Ma, Jun-Ying Ju, Jian-Hua Wu, Hui Zhao, Ming Wang, Ruida An, Fa-Liang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;Marine Biomed Sci & Technol Innovat Platform Lin;Anhui Polytech Univ
- 来源：BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS 2023
- 关键词：Ilamycins Anti-tuberculosis Streptomyces atratus SCSIO ZH16 Entromorpha prolifera BldD
- Combinatorial strategies for production improvement of anti-tuberculosis antibiotics ilamycins E1/E2 from deep sea-derived Streptomyces atratus SCSIO ZH16 ΔilaR被引量：4收藏
- 作者：Zhu, Yunfei Zheng, Gaofan Xin, Xiujuan Ma, Junying Ju, Jianhua An, Faliang
- 机构：East China Univ Sci & Technol;Chinese Acad Sci
- 来源：BIORESOURCES AND BIOPROCESSING 2022
- 关键词：Ilamycins Streptomyces atratus Fermentation optimization Exogenous adding strategy
- Edible-plant derived 2′,4′-dihydroxy-6′-methoxy-3′,5′-dimethylchalcone exert dual effects on invigorating triple-negative breast cancer apoptosis被引量：1收藏
- 作者：Yu, Tingting Jiang, Yu Guo, Miaomiao Wei, Xing Xin, Xiujuan An, Faliang
- 机构：East China Univ Sci & Technol;Beijing Technol & Business Univ;Marine Biomed Sci & Technol Innovat Platform Linga
- 来源：FOOD BIOENGINEERING 2024
- 关键词：DMC G(2)/M arrest MDA-MB-231 cells PI3K/Akt/mTOR pathway beta-tubulin binding
- Balancing nitrogen metabolism to efficiently drive anti-tuberculosis ilamycins biosynthesis in Streptomyces atratus被引量：0收藏
- 作者：Zheng, Gaofan Zhou, Weiyan Gui, Yingyue Jiang, Yuxi Zhu, Yunfei Ma, Junying Ju, Jianhua Xin, Xiujuan Li, Baoli Wang, Ruida Zhao, Ming An, Faliang
- 机构：East China Univ Sci & Technol;Anhui Polytech Univ;East China Univ Sci & Technol;Marine Biomed Sci & Technol Innovat Platform Lin G;Chinese Acad Sci
- 来源：BIORESOURCE TECHNOLOGY 2025
- 关键词：Ilamycins Anti-tuberculosis Nitrogen metabolism balance RNA sequencing S. atratus SCSIO ZH16
- Protection effect of 20(S)-ginsenoside Rg2 extracted from cultured Panax notoginseng cells on hydrogen peroxide-induced cytotoxity of human umbilical cord vEIn endothelial cells in vitro被引量：0收藏
- 作者：Xin, Xiujuan Zhong, Jianjiang Wei, Dongzhi Liu, Jianwen
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Process Biochemistry 2005
- 关键词：Oxygen
- Strategy of employing plug-and-play vectors and LC-MS screening to facilitate the discovery of natural products using Aspergillus oryzae被引量：0收藏
- 作者：Shi, Hanliang Lin, Beibei Zheng, Mengmeng Gan, Fengyu Lin, Zhi Xin, Xiujuan Zhao, Jian Qu, Xudong An, Faliang
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Wuhan Univ;Shanghai Jiao Tong Univ;East China Univ Sci & Technol
- 来源：BIORESOURCES AND BIOPROCESSING 2025
- 关键词：Plug-and-play vectors LC-MS detection
Aspergillus oryzae Heterologous expression PamyB
- Synergistic antifungal activity and mechanism of piroctone olamine and sorbitan caprylate against Malassezia restricta被引量：0收藏
- 作者：Yu, Jiewen Guo, Jiacheng Gong, Lizhi Xia, Dandan Chang, Xiaowei Xin, Xiujuan He, Jingjing An, Faliang
- 机构：East China Univ Sci & Technol;Shanghai R&D Ctr Proya Cosmet Co Ltd;JiangNing Hosp Chinese Med;Marine Biomed Sci & Technol Innovat Platform Linga
- 来源：JOURNAL OF APPLIED MICROBIOLOGY 2026
- 关键词：Malassezia restricta piroctone olamine sorbitan caprylate cell membrane ergosterol
