成果/Result
- Curcumin-based polarity fluorescent probes: Design strategy and biological applications被引量：41收藏
- 作者：Hu, Linghao Shi, Donglei Li, Xinming Zhu, Jin Mao, Fei Li, Xiaokang Xia, Conglong Jiang, Bei Guo, Yuan Li, Jian
- 机构：East China Univ Sci & Technol;Northwest Univ;Dali Univ
- 来源：DYES AND PIGMENTS 2020
- 关键词：Curcumin Polarity-specificity Polarity fluorescent probe Lysosome Live-cell imaging Design strategy
- Melting Point Distribution Analysis of Globally Approved and Discontinued Drugs: A Research for Improving the Chance of Success of Drug Design and Discovery被引量：32收藏
- 作者：Mao, Fei Kong, Qingya Ni, Wei Xu, Xiang Ling, Dazheng Lu, Zhengyu Li, Jian
- 机构：East China Univ Sci & Technol
- 来源：CHEMISTRYOPEN 2016
- 关键词：approved drugs discontinued drugs drug design and discovery drug-like properties Lipinskis rule of five melting point distribution
- Design, Synthesis and Therapeutic Evaluation of Novel Antimalarial Derivatives Based on the Clinical Antitumor Candidate Drug Quisinostat被引量：32收藏
- 作者：Li, Jian Song, Jiamei Li, Ruoxi Huang, Zhenghui Qian, Yunan Wang, Xicheng Shao, Qiqi Mao, Fei Wang, Manjiong Jiang, Lubin Li, Xiaokang
- 机构： State Key Laboratory of Bioreactor Engineering; Key Laboratory of Molecular Virology and Immunology; Key Laboratory of Xinjiang Phytomedicine Resource and Utilization; Key Laboratory of Tropical Biological Resources of Ministry of Education; Nanjing Advanced Academy of Life and Health
- 来源：SSRN 2024
- 关键词：Acetylation - Diseases - Electrophoresis - Structural optimization
- Targeting GRP75 with a Chlorpromazine Derivative Inhibits Endometrial Cancer Progression Through GRP75-IP3R-Ca2+-AMPK Axis被引量：20收藏
- 作者：Wang, Qi Li, Lijuan Gao, Xiaoyan Zhang, Chunxue Xu, Chen Song, Lingyi Li, Jian Sun, Xiao Mao, Fei Wang, Yudong
- 机构：Shanghai Jiao Tong Univ;East China Univ Sci & Technol
- 来源：ADVANCED SCIENCE 2024
- 关键词：chlorpromazine endometrial cancer GRP75 MAM
- A rapid-response near-infrared fluorescent probe with a large Stokes shift for senescence-associated β-galactosidase activity detection and imaging of senescent cells被引量：19收藏
- 作者：Qiu, Wenjing Li, Xiaokang Shi, Donglei Li, Xinming Gao, Ying Li, Jinwen Mao, Fei Guo, Yuan Li, Jian
- 机构：East China Univ Sci & Technol;Northwest Univ;Dali Univ;East China Univ Sci & Technol
- 来源：DYES AND PIGMENTS 2020
- 关键词：Senescence-associated beta-galactosidase NIR fluorescent probe Aging Senescent cells Living-cell imaging
