成果/Result
- Secondary Amine Pendant β-Peptide Polymers Displaying Potent Antibacterial Activity and Promising Therapeutic Potential in Treating MRSA-Induced Wound Infections and Keratitis被引量：124收藏
- 作者：Qian, Yuxin Deng, Shuai Cong, Zihao Zhang, Haodong Lu, Ziyi Shao, Ning Bhatti, Sonia Abid Zhou, Cong Cheng, Jiagao Gellman, Samuel H. Liu, Runhui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Wisconsin
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2022
- 关键词：Amines - Antibiotics - Cytotoxicity - Amino acids - Functional polymers
- Rational Exploration of Novel SDHI Fungicide through an Amide-?-ketonitrile Bioisosteric Replacement Strategy被引量：42收藏
- 作者：Zhou, Cong Sun, Xujuan Fu, Wen Li, Zhong Cheng, Jiagao Maienfisch, Peter
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2023
- 关键词：?-ketonitriles succinate dehydrogenase inhibitors fungicidal activity bioisosteric replacement molecular docking 3D-QSAR
- Silicon-Containing Complex II Acaricides-Design, Synthesis, and Pharmacological Optimization被引量：30收藏
- 作者：Zhou, Cong Wang, Xin Quan, Xiaocao Cheng, Jiagao Li, Zhong Maienfisch, Peter
- 机构：East China Univ Sci & Technol;CreInSol MCB
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2022
- 关键词：carbon-silicon bioisosteric replacements silicon-containing drugs and pesticides complex II acaricides cyflumetofen structure-activity relationship mode of action computational modeling
- Reversible Regulation of Succinate Dehydrogenase by Tools of Photopharmacology被引量：28收藏
- 作者：Fu, Wen Shao, Zhongli Sun, Xujuan Zhou, Cong Xu, Zhiping Zhang, Yang Cheng, Jiagao Li, Zhong Shao, Xusheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2022
- 关键词：regulation SDH photochromic ligands azobenzene optical control
- Anthranilic Diamides Containing Monofluoroalkene Amide Linkers as Potential Insect RyR Activators: Design, Synthesis, Bio-evaluation, and Computational Study被引量：23收藏
- 作者：Yang, Guantian Zhou, Cong Wang, Yutong Li, Yuxin Gu, Yucheng Li, Zhong Cheng, Jiagao Xu, Xiaoyong
- 机构：East China Univ Sci & Technol;Nankai Univ;Syngenta
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2023
- 关键词：anthranilic diamides ryanodine receptor insecticidal activity acrylamide monofluoroalkene
- Discovery of Potential Neonicotinoid Insecticides by an Artificial Intelligence Generative Model and Structure-Based Virtual Screening被引量：13收藏
- 作者：Kong, Yijin Zhou, Cong Tan, Du Xu, Xiaoyong Li, Zhong Cheng, Jiagao
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2024
- 关键词：neonicotinoid insecticides generative model transfer learning virtual screening moleculardynamics simulations
- Design, Synthesis, and Insecticidal Evaluation of N-Pyridylpyrazole Amide Derivatives Containing 4,5-Dihydroisoxazole Amide as Potential Ryanodine Receptor Activators被引量：10收藏
- 作者：Pang, Xiwen Han, Li Zhou, Cong Li, Yuxin Xu, Xiaoyong Shao, Xusheng Li, Zhong
- 机构：East China Univ Sci & Technol;Nankai Univ
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2023
- 关键词：anthranilic diamides 4,5-dihydroisoxazol insecticidal activity ryanodine receptor
- Computational Modeling Oriented Substructure Splicing Application in the Identification of Thiazolidine Derivatives as Potential Low Honeybee Toxic Neonicotinoids被引量：6收藏
- 作者：Zhou, Cong Kong, Yijin Zhang, Huihui Zhai, Na Li, Zhong Qian, Xuhong Liu, Zewen Cheng, Jiagao
- 机构：East China Univ Sci & Technol;Nanjing Agr Univ;East China Normal Univ
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2024
- 关键词：neonicotinoid insecticides thiazolidine derivatives insecticidal activity bee toxicity acetylcholinebinding protEIn
- Novel Acaricidal Silico-Containing Pyrazolyl Acrylonitrile Derivatives Identified through Rational Carbon-Silicon Bioisosteric Replacement Strategy被引量：5收藏
- 作者：Zhou, Cong Li, Zhong Qian, Xuhong Cheng, Jiagao Maienfisch, Peter
- 机构：East China Univ Sci & Technol;East China Normal Univ;CreInSol MCB
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2023
- 关键词：carbon-siliconbioisosteric replacement pyrazolylacrylonitrile acaricides cyenopyrafen cyetpyrafen complex II binding site structure activity relationship computational modeling
- Discovery of Novel Nicotinamide Derivatives by a Two-Step Strategy of Azo-Incorporating and Bioisosteric Replacement被引量：5收藏
- 作者：Ru, Yifan Fu, Wen Guo, Sifan Li, Xiaoyan Zhou, Cong Xu, Zhiping Cheng, Jiagao Li, Zhong Shao, Xusheng
- 机构：East China Univ Sci & Technol;Yantai Inst China Agr Univ;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2024
- 关键词：nicotinamide azo-incorporating bioisostericreplacement fungicidal spectrum SDH
- Identification of potential novel insect TRPV channel modulators by homology modeling, binding mode analysis, virtual screening studies and chemical optimization被引量：3收藏
- 作者：Li, Xiaoyang Zhou, Cong He, Lujue Xu, Zhiping Li, Zhong Cheng, Jiagao
- 机构：East China Univ Sci & Technol
- 来源：NEW JOURNAL OF CHEMISTRY 2024
- 关键词：Binding energy - Binding sites - Modulators - Pyridine - Scaffolds
- Discovery of Novel Neonicotinoids with Conjugated Diene Enabled by Cascade Allylation/Isomerization Synthetic Methodology被引量：3收藏
- 作者：Zhang, Dongxu Zhou, Cong Qi, Suzhen Zhang, Huihui Shao, Xusheng Xu, Xiaoyong Cheng, Jiagao Liu, Zewen Li, Zhong Yang, Wu-Lin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Agr Sci;Nanjing Agr Univ
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2025
- 关键词：neonicotinoid insecticides insect resistance bee toxicity conjugated system insecticidal activity cascade reaction
- Novel Synthetic Method and Insecticidal Evaluation of CF3-Containing Polycyclic Neonicotinoid Derivatives被引量：2收藏
- 作者：Zeng, Xiaoqin Zhou, Cong Xu, Qian Shao, Xusheng Xu, Xiaoyong Cheng, Jiagao Yang, Wu-Lin Li, Zhong
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2025
- 关键词：neonicotinoid insecticides insecticidal activity trifluoromethyl group annulation reaction molecular docking
- Discovery of Novel Pyrazole β-Ketonitrile Derivatives as Broad Spectrum SDHI Fungicides by Introducing a Flexible Motif被引量：2收藏
- 作者：Cheng, Liangliang Wang, Hanting Zhou, Cong Qin, Jiawei Li, Zhong Cheng, Jiagao
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2025
- 关键词：fungicide succinate dehydrogenase inhibitors beta-ketonitriles molecular docking molecularflexibility
- Recent Advancesand Prospects of Succinate DehydrogenasEInhibitor Acaricides被引量：0收藏
- 作者：Zhou, Cong Gao, Zihang Li, Zhong Qian, Xuhong Maienfisch, Peter Cheng, Jiagao
- 机构：East China Univ Sci & Technol;CreInSol MCB;Guizhou Univ
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2026
- 关键词：acaricides succinate dehydrogenasEInhibitor mode of action acaricide resistance
- Discovery of Novel 2,4,5-Trisubstituted Oxazoline Derivatives as Potent Acaricidal Agents被引量：0收藏
- 作者：Chang, Wenning Wang, En Zhou, Cong Zhai, Na Shao, Xusheng Xu, Xiaoyong Cheng, Jiagao Yang, Wu-Lin Li, Zhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2025
- 关键词：etoxazole acaricidal activity molecular docking density functional theory calculations zebrafish toxicity
- Discovery of Novel Flexible β-Ketonitrile Derivatives Bearing a Biphenyl Moiety as Potential Succinate Dehydrogenase Inhibitors被引量：0收藏
- 作者：Cheng, Liangliang Wang, Sihui Zhou, Cong Zhai, Na Wu, Biao Li, Zhong Cheng, Jiagao
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2025
- 关键词：biphenyl beta-ketonitriles succinate dehydrogenasEInhibitors fungicidal activity molecular docking
- Rational Design of β-Ketonitrile Acaricides through Binding-Mode-Guided Isosteric Ring Replacement被引量：0收藏
- 作者：Zhou, Cong Ge, Jingwen Li, Zhong Qian, Xuhong Maienfisch, Peter Cheng, Jiagao
- 机构：East China Univ Sci & Technol;East China Normal Univ;CreInSol MCB;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2026
- 关键词：beta-ketonitrile acaricide isosteric ring replacement structure activity relationship mode of action computational modeling
- Facile construction of a dual pH/redox-responsive nanopesticide for precise control of Fusarium graminearum with enhanced biosafety被引量：0收藏
- 作者：Sun, Li Xing, Demei Li, Zhen Gao, Yanyan Peng, Yue Zhang, Jiale Gao, Yue Gong, Ruihan Zhou, Cong Cheng, Jiagao
- 机构：East China Univ Sci & Technol;Yangzhou Univ;East China Univ Sci & Technol
- 来源：CHEMICAL ENGINEERING JOURNAL 2026
- 关键词：Nanopesticide Metal-organic frameworks Metal-phenolic network Environmentally responsive Fusarium graminearum Biosafety
- Discovery of Novel Diamides Scaffold Containing Monofluoro-acrylamides Activating the Insect Ryanodine Receptor被引量：0收藏
- 作者：Yang, Guantian Wang, Yutong Zhou, Cong Li, Yuxin Gu, Yucheng Li, Zhong Xu, Zhiping Cheng, Jiagao Xu, Xiaoyong
- 机构：East China Univ Sci & Technol;Nankai Univ;Jealotts Hill Int Res Ctr
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2023
- 关键词：diamide insecticide ryanodine receptor acrylamide monofluoroalkene 3D-QSAR calcium imaging molecular docking
