成果/Result
- Direct Asymmetric Synthesis of β-Bis-Aryl-α-Amino Acid Esters via Enantioselective Copper-Catalyzed Addition of p-Quinone Methides被引量：170收藏
- 作者：He, Fu-Sheng Jin, Jing-Hai Yang, Zhong-Tao Yu, Xingxin Fossey, John S. Deng, Wei-Ping
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Univ Birmingham
- 来源：ACS CATALYSIS 2016
- 关键词：unnatural alpha-amino acids asymmetric catalysis copper conjugate addition para-quinone methides
- Highly Enantioselective Rhodium-Catalyzed Addition of Arylboroxines to Simple Aryl Ketones: Efficient Synthesis of Escitalopram被引量：78收藏
- 作者：Huang, Linwei Zhu, Jinbin Jiao, Guangjun Wang, Zheng Yu, Xingxin Deng, Wei-Ping Tang, Wenjun
- 机构：E China Inst Theoret Phys;Chinese Acad Sci;AstraZeneca Global R&D
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2016
- 关键词：asymmetric catalysis enantioselectivity ligand design rhodium total synthesis
- Cu(I)-Catalyzed Chemoselective and Stereoselective [3+3] Cycloaddition of Azomethine Ylides with 2-Indolylnitroethylenes: Facile Access to Highly Substituted Tetrahydro-γ-Carbolines被引量：66收藏
- 作者：Yang, Wu-Lin Li, Chun-Yan Qin, Wen-Jing Tang, Fei-Fei Yu, Xingxin Deng, Wei-Ping
- 机构：East China Univ Sci & Technol; East China Univ Sci & Technol
- 来源：ACS CATALYSIS 2016
- 关键词：asymmetric catalysis chemoselectivity cycloaddition azomethine ylide tetrahydro-gamma-carboline
- Unexpected O-H Insertion of Rhodium-Azavinylcarbenes with N-Acylhydrazones: Divergent Synthesis of 3,6-Disubstituted- and 3,5 6-Trisubstituted-1,2,4-Triazines被引量：34收藏
- 作者：Meng, Jiang Wen, Min Zhang, Shiwei Pan, Peiwen Yu, Xingxin Deng, Wei-Ping
- 机构：East China Univ Sci & Technol; East China Univ Sci & Technol
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2017
- 关键词：Cyclization - Ketones - Reaction intermediates
- Rhodium(II)-Catalyzed Reaction of 1-Tosyl-1,2,3-triazoles with Morita-Baylis-Hillman Adducts: Synthesis of 3,4-Fused Pyrroles被引量：30收藏
- 作者：Jia, Renmeng Meng, Jiang Leng, Jiaying Yu, Xingxin Deng, Wei-Ping
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHEMISTRY-AN ASIAN JOURNAL 2018
- 关键词：pyrroles rhodium catalyzed synthetic methods triazoles
- Chiral N,O-Ligand/[Cu(OAc)2]-Catalyzed Asymmetric Construction of 4-Aminopyrrolidine Derivatives by 1,3-Dipolar Cycloaddition of Azomethine Ylides with -Phthalimidoacrylates被引量：29收藏
- 作者：Wang, Zheng Yu, Xingxin Tian, Bo-Xue Payne, Daniel T. Yang, Wu-Lin Liu, Yang-Zi Fossey, John S. Deng, Wei-Ping
- 机构：East China Univ Sci & Technol;Univ Calif San Francisco;Univ Birmingham
- 来源：CHEMISTRY-A EUROPEAN JOURNAL 2015
- 关键词：asymmetric synthesis copper cycloaddition density functional calculations ligands
- Cu(OAc)2/FOXAP complex catalyzed construction of 2,5-dihydropyrrole derivatives via asymmetric 1,3-dipolar cycloaddition of azomethine ylides to ethynyl ketones被引量：28收藏
- 作者：Tang, Fei-Fei Yang, Wu-Lin Yu, Xingxin Deng, Wei-Ping
- 机构：E China Univ Sci & Technol
- 来源：CATALYSIS SCIENCE & TECHNOLOGY 2015
- 关键词：Catalysis - Ketones
- XGraphCDS: An explainable deep learning model for predicting drug sensitivity from gene pathways and chemical structures被引量：15收藏
- 作者：Wang, Yimeng Yu, Xinxin Gu, Yaxin Li, Weihua Zhu, Keyun Chen, Long Tang, Yun Liu, Guixia
- 机构：East China Univ Sci & Technol
- 来源：COMPUTERS IN BIOLOGY AND MEDICINE 2024
- 关键词：Cancer drug sensitivity prediction Deep learning Gene pathways Chemical structures Interpretation
- Kinetic Resolution of α-Methylene-β-hydroxy Esters Catalyzed by Acyl Transfer Catalyst An-PIQ被引量：13收藏
- 作者：Jiang, Shan-Shan Xu, Qin-Chang Zhu, Ming-Yu Yu, Xingxin Deng, Wei-Ping
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2015
- 关键词：Esters
- Enantioselective Rhodium-Catalyzed Addition of Arylboroxines to N-Unprotected Ketimines: Efficient Synthesis of Cipargamin被引量：12收藏
- 作者：Zhu, Jinbin Huang, Linwei Dong, Wei Li, Naikai Yu, Xingxin Deng, Wei-Ping Tang, Wenjun
- 机构：East China Univ Sci & Technol;Chinese Acad Sci
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2019
- 关键词：asymmetric catalysis enantioselectivity ketimines Pligands rhodium
- Silver(I) and Copper(I) Cocatalyzed Tandem Reaction of 2-Alkynylbenzaldoximes with Aldehydes or Alcohols: Approach to 4-Carboxylated Isoquinolines被引量：9收藏
- 作者：Wang, Xianbo Yu, Xingxin
- 机构：Nanchang Univ;E China Univ Sci & Technol
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2014
- 关键词：Copper compounds - Silver compounds
- GCLmf: A Novel Molecular Graph Contrastive Learning Framework Based on Hard Negatives and Application in Toxicity Prediction被引量：3收藏
- 作者：Yu, Xinxin Chen, Yuanting Chen, Long Li, Weihua Wang, Yuhao Tang, Yun Liu, Guixia
- 机构：East China Univ Sci & Technol
- 来源：MOLECULAR INFORMATICS 2025
- 关键词：chemical toxicity graph contrastive learning GNN hard negatives molecular representation self-supervised learning
