成果/Result
- Discovery of Potent and Noncovalent Reversible EGFR Kinase Inhibitors of EGFRL858R/T790M/C797S被引量：59收藏
- 作者：Li, Qiannan Zhang, Tao Li, Shiliang Tong, Linjiang Li, Junyu Su, Zhicheng Feng, Fang Sun, Deheng Tong, Yi Wang, Xia Zhao, Zhenjiang Zhu, Lili Ding, Jian Li, Honglin Xie, Hua Xu, Yufang
- 机构：East China Univ Sci & Technol;Chinese Acad Sci
- 来源：ACS MEDICINAL CHEMISTRY LETTERS 2019
- 关键词：EGFR mutant inhibitor C797S
- Biospecific Self-Assembly of a Nanoparticle Coating for Targeted and Stimuli-Responsive Drug Delivery被引量：54收藏
- 作者：Li, Jinyang Qu, Xue Payne, Gregory F. Zhang, Cheng Zhang, Yuxin Li, Jianbo Ren, Jie Hong, Hua Liu, Changsheng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Inst Biosyst & Biotechnol Res;Fischell Dept Bioengn;Tongji Univ
- 来源：ADVANCED FUNCTIONAL MATERIALS 2015
- 关键词：Cells - Glycoproteins - Cancer cells - Cell culture - Diseases - Proteins - Medical nanotechnology - Self assembly - Silica nanoparticles
- Structural diversity and applications of lipopeptide biosurfactants as biocontrol agents against phytopathogens: A review被引量：47收藏
- 作者：Sani, Asma Qin, Wan-Qi Li, Jia-Yi Liu, Yi-Fan Zhou, Lei Yang, Shi-Zhong Mu, Bo-Zhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：MICROBIOLOGICAL RESEARCH 2024
- 关键词：Microbial lipopeptide Structural diversity Wettability alteration Biocontrol Pesticide
- Microbial Lipopeptide-Producing Strains and Their Metabolic Roles under Anaerobic Conditions被引量：25收藏
- 作者：Li, Jia-Yi Wang, Lu Liu, Yi-Fan Zhou, Lei Gang, Hong-Ze Liu, Jin-Feng Yang, Shi-Zhong Mu, Bo-Zhong
- 机构：East China Univ Sci & Technol;CNPN;East China Univ Sci & Technol
- 来源：MICROORGANISMS 2021
- 关键词：biosurfactant anaerobic bacteria nitrate respiration non-ribosomal peptide synthetase (NRPSs)
- Nitroreductase Increases Menadione-Mediated Oxidative Stress in Aspergillus nidulans被引量：24收藏
- 作者：Zhou, Yao Lv, Hangya Li, Haoxiang Li, Jingyi Yan, Yunfeng Liu, Feiyun Hao, Wenliang Zhou, Zhemin Wang, Ping Zhou, Shengmin
- 机构：East China Univ Sci & Technol;Jiangnan Univ
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2021
- 关键词：Aspergillus nidulans menadione nitroreductase oxidative stress ROS resistance
- Template size matched film thickness for effectively in situ surface imprinting: a model study of glycoprotein imprints被引量：22收藏
- 作者：Wu, Gang Li, Jinyang Qu, Xue Zhang, Yuxin Hong, Hua Liu, Changsheng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：RSC ADVANCES 2015
- 关键词：Binding sites - Film thickness - Thin films - Enzyme immobilization - Deposition - Glucose sensors - Magnetite - Glucose oxidase - Glycoproteins
- Biofabricated Nanoparticle Coating for Liver-Cell Targeting被引量：14收藏
- 作者：Zhang, Cheng Qu, Xue Li, Jinyang Hong, Hua Li, Jianbo Ren, Jie Payne, Gregory F. Liu, Changsheng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Tongji Univ;Inst Biosyst & Biotechnol Res;Fischell Dept Engn
- 来源：ADVANCED HEALTHCARE MATERIALS 2015
- Establishment and Application of Event-Specific Polymerase Chain Reaction Methods for Two Genetically Modified Soybean Events, A2704-12 and A5547-127被引量：14收藏
- 作者：Li, Xiang Pan, Liangwen Li, Junyi Zhang, Qigang Zhang, Shuya Lv, Rong Yang, Litao
- 机构：Shanghai Entry Exit Inspect & Quarantine Bur;E China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2011
- 关键词：A2704-12 A5547-127 event-specific PCR routine analysis
- Increasing NADPH impairs fungal H2O2 resistance by perturbing transcriptional regulation of peroxiredoxin被引量：11收藏
- 作者：Li, Jingyi Sun, Yanwei Liu, Feiyun Zhou, Yao Yan, Yunfeng Zhou, Zhemin Wang, Ping Zhou, Shengmin
- 机构：East China Univ Sci & Technol;Jiangnan Univ;Univ Minnesota
- 来源：BIORESOURCES AND BIOPROCESSING 2022
- 关键词：Peroxiredoxin NADPH Oxidative stress Aspergillus Glucose-6-phosphate dehydrogenase AnCF
- Novel peroxiredoxin-based sensor for sensitive detection of hydrogen peroxide被引量：10收藏
- 作者：Yang, Yuhong Zhou, Yao Li, Jingyi Yu, Haijun Takaya, Naoki Wang, Ping Zhou, Shengmin
- 机构：East China Univ Sci & Technol;Univ Tsukuba
- 来源：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2019
- 关键词：Hydrogen peroxide Biosensor Peroxiredoxin Thioredoxin Sensitive detection
- Cloning and Characterization of Filamentous Fungal S-Nitrosoglutathione Reductase from Aspergillus nidulans被引量：8收藏
- 作者：Zhou, Yao Zhou, Shengmin Yu, Haijun Li, Jingyi Xia, Yang Li, Baoyi Wang, Xiaoli Wang, Ping
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF MICROBIOLOGY AND BIOTECHNOLOGY 2016
- 关键词：S-Nitrosoglutathione reductase nitrosation denitrosation nitric oxide Aspergillus nidulans
- Cytosol Peroxiredoxin and Cell Surface Catalase Differentially Respond to H2O2 Stress in Aspergillus nidulans被引量：8收藏
- 作者：Yan, Yunfeng Huang, Xiaofei Zhou, Yao Li, Jingyi Liu, Feiyun Li, Xueying Hu, Xiaotao Wang, Jing Guo, Lingyan Liu, Renning Takaya, Naoki Zhou, Shengmin
- 机构：East China Univ Sci & Technol;Univ Tsukuba
- 来源：ANTIOXIDANTS 2023
- 关键词：peroxiredoxin catalase oxidative stress hydrogen peroxide Aspergillus nidulans
- Genetic engineering of circularly permuted yellow fluorescent protein reveals intracellular acidification in response to nitric oxide stimuli被引量：8收藏
- 作者：Deng, Haitao Li, Jingyi Zhou, Yao Xia, Yang Chen, Chao Zhou, Zhemin Wu, Hui Wang, Ping Zhou, Shengmin
- 机构：East China Univ Sci & Technol;Jiangnan Univ
- 来源：REDOX BIOLOGY 2021
- 关键词：Fluorescent probe cpYFP pH indicator Nitric oxide
- Characterization of the promoter of the nitrate transporter-encoding gene nrtA in Aspergillus nidulans被引量：4收藏
- 作者：Liu, Yangyi Li, Haoxiang Li, Jingyi Zhou, Yao Zhou, Zhemin Wang, Ping Zhou, Shengmin
- 机构：East China Univ Sci & Technol;Jiangnan Univ;Univ Minnesota
- 来源：MOLECULAR GENETICS AND GENOMICS 2020
- 关键词：Aspergillus nidulans Nitrate transporter NrtA Promoter Transcription regulation
- Protein disulfide isomerase 1 is required for RodA assembling-based conidial hydrophobicity of Aspergillus fumigatus被引量：3收藏
- 作者：Hu, Xiaotao Zhou, Yao Liu, Renning Wang, Jing Guo, Lingyan Huang, Xiaofei Li, Jingyi Yan, Yunfeng Liu, Feiyun Li, Xueying Tan, Xinyu Luo, Yiqing Wang, Ping Zhou, Shengmin
- 机构：East China Univ Sci & Technol;Univ Minnesota Twin Cities
- 来源：APPLIED AND ENVIRONMENTAL MICROBIOLOGY 2024
- 关键词：conidial hydrophobicity protein disulfide isomerase Aspergillus rodlet layer RodA
- Structural and compositional diversity of biosurfactants produced by a novel strain of Sporosarcina luteola ME44 from oil reservoir被引量：3收藏
- 作者：Li, Jia-Yi Liu, Yi-Fan Zhou, Lei Gang, Hong-Ze Liu, Jin-Feng Sun, Gang-Zheng Wang, Wei-Dong Yang, Shi-Zhong Mu, Bo-Zhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Daqing Huali Biotechnol Co Ltd;Sinopec
- 来源：JOURNAL OF ENVIRONMENTAL QUALITY 2024
- 关键词：Biomineralization - Biomolecules - Biotechnology - Cadmium compounds - Copper compounds - High performance liquid chromatography - Mass spectrometry - Metal ions - Petroleum reservoir engineering - Silver compounds - Surface active agents - Zinc compounds
- Methanogenic biodegradation of thermoplastic poly(vinyl alcohol) films produced by two manufacturing processes in enrichment cultures被引量：3收藏
- 作者：Ji, Ming-Le Liu, Yi-Fan Bai, Yu Hu, Zhen Wang, James H. Li, Jia-Yi Qin, Wan-Qi Zhou, Lei Yang, Shi-Zhong Gu, Ji-Dong Li, Yingcheng Mu, Bo-Zhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Sinopec Shanghai Res Inst Petrochem Technol Co Ltd;Guangdong Technion Israel Inst Technol;East China Univ Sci & Technol
- 来源：INTERNATIONAL BIODETERIORATION & BIODEGRADATION 2024
- 关键词：Biodegradable plastics Thermoplastic polyvinyl alcohol (TPVA) Anaerobic biodegradation Microbial community Biodegradation pathway
- A new biosurfactant-producing strain, Fictibacillus nanhaiensis ME46, isolated from an oil field in China被引量：3收藏
- 作者：Li, Jia-Yi Liu, Yi-Fan Zhou, Lei Gang, Hong-Ze Liu, Jin-Feng Sun, Gang-Zheng Wang, Wei-Dong Yang, Shi-Zhong Mu, Bo-Zhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Daqing Huali Biotechnol Co Ltd;Sinopec
- 来源：ENVIRONMENTAL TECHNOLOGY 2024
- 关键词：Biosurfactant surfactin endospore-forming bacteria Fictibacillus nanhaiensis
- ADP-ribose is a competitive inhibitor of methanol dehydrogenases from Bacillus methanolicus被引量：2收藏
- 作者：Ma, Bao-Di Li, Jia-Yi Xu, Jian-He Yu, Tao Kong, Xu-Dong
- 机构：Shanghai Jiao Tong Univ;Shanghai Jiao Tong Univ;Shanghai Inst Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：JOURNAL OF BIOLOGICAL CHEMISTRY 2025
- 关键词：Bacteriology - Biochemistry - Chemical activation - Crystallography - Hydrolases - Hydrolysis - Metabolic engineering - Metabolism - Methanol
- Peroxiredoxin PrxA and thioredoxin TrxA mediate the redox signal to the transcription factor NapA in the fungus Aspergillus nidulans被引量：2收藏
- 作者：Liu, Feiyun Guo, Lingyan Luo, Yiqing Li, Jingyi Zhou, Yao Wang, Jing Huang, Xiaofei Tan, Xinyu Fu, Mingxin Yu, Bingzi Gao, Yan Liu, Renning Takaya, Naoki Zhou, Shengmin
- 机构：East China Univ Sci & Technol;Peking Univ;Univ Tsukuba
- 来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2025
- 关键词：Peroxiredoxin Thioredoxin H 2 O 2 signal
- Exploring genetic codon expansion for unnatural amino acid incorporation in filamentous fungus Aspergillus nidulans被引量：0收藏
- 作者：Li, Xueying Wang, Jing Li, Jingyi Zhou, Yao Huang, Xiaofei Guo, Lingyan Liu, Renning Luo, Yiqing Tan, Xinyu Hu, Xiaotao Gao, Yan Yu, Bingzi Fu, Mingxin Wang, Ping Zhou, Shengmin
- 机构：East China Univ Sci & Technol;Univ Minnesota
- 来源：JOURNAL OF BIOTECHNOLOGY 2024
- 关键词：Unnatural amino acid Amber suppression Filamentous fungus Aspergillus Genetic codon expansion
- Dual-single-guide RNA strategy improves CRISPR-mediated homology-directed repair in Aspergillus被引量：0收藏
- 作者：Fu, Mingxin Wang, Jing Li, Jingyi Zhou, Yao Huang, Xiaofei Jia, Zehan Luo, Yiqing Tan, Xinyu Gao, Yan Yu, Bingzi Duan, Yuting Bu, Qianyun Li, Xiaoying Wang, Yifan Takaya, Naoki Zhou, Shengmin
- 机构：East China Univ Sci & Technol;Univ Tsukuba;Peking Univ
- 来源：NUCLEIC ACIDS RESEARCH 2026
- Phospholipid membrane permeabilization and leakage of cell content by surfactin-C15 from novel B. subtilis B-11 strain: a computational and experimental analysis被引量：0收藏
- 作者：Sani, Asma Li, Jia-Yi Ali, Chaudhry Haider Gang, Hong-Ze Liu, Yi-Fan Yang, Shi-Zhong Mu, Bo-Zhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Engn & Technol
- 来源：INTERNATIONAL MICROBIOLOGY 2025
- 关键词：Surfactin Membrane permeabilization Phospholipid vesicle Membrane-water interface Phytopathogenic inhibition
- Increasing NADPH impairs fungal H?O? resistance by perturbing transcriptional regulation of peroxiredoxin被引量：0收藏
- 作者：Jingyi Li Yanwei Sun Feiyun Liu Yao Zhou Yunfeng Yan Zhemin Zhou Ping Wang Shengmin Zhou
- 机构：State Key Laboratory of Bioreactor Engineering;Key Laboratory of Industrial Biotechnology(Ministry of Education);Department of Bioproducts and Biosystems Engineering
- 来源：生物资源与生物加工(英文) 2022
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- Fungal oxidative stress tolerance depends on peroxiredoxin PrxA-mediated redox signaling to mitochondrial cytochrome c peroxidase Ccp1被引量：0收藏
- 作者：Huang, Xiaofei Gao, Yan Yu, Bingzi Jia, Zehan Luo, Yiqing Fu, Mingxin Duan, Yuting Bu, Qianyun Li, Xiaoying Wang, Jing Tan, Xinyu Guo, Lingyan Li, Jingyi Zhou, Yao Zhang, Xiaohui Takaya, Naoki Zhou, Shengmin
- 机构：East China Univ Sci & Technol;Peking Univ;Univ Tsukuba
- 来源：JOURNAL OF BIOLOGICAL CHEMISTRY 2026
- 关键词：Antioxidants - Catalyst activity - Cell membranes - Functional analysis - Mitochondria - Oxidative stress - Praseodymium compounds - Signaling
- Structural Diversity of the Lipopeptide Biosurfactant Produced by a Newly Isolated Strain, Geobacillus thermodenitrifcans ME63被引量：0收藏
- 作者：Li, Jia-Yi Liu, Yi-Fan Zhou, Lei Gang, Hong-Ze Liu, Jin-Feng Sun, Gang-Zheng Wang, Wei-Dong Yang, Shi-Zhong Mu, Bo-Zhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Daqing Huali Biotechnol Co Ltd
- 来源：ACS OMEGA 2023
- Biochemical and structural characterization of a novel nicotinamide mononucleotide adenylyltransferase from thermophilic fungi Chaetomium thermophilum被引量：0收藏
- 作者：Qian, Xiao-Long Li, Jia-Yi Li, Chun-Xiu Pan, Jiang Mu, Bozhong Xu, Jian-He
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Suzhou Bioforany EnzyTech Co Ltd
- 来源：BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS 2025
- 关键词：Nicotinamide mononucleotide adenylyltransferase Crystal structure Characterization Chaetomium thermophilum NAD(+) synthesis
