成果/Result
- SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents被引量：321收藏
- 作者：Zhao, Yuzheng Hu, Qingxun Cheng, Feixiong Su, Ni Wang, Aoxue Zou, Yejun Hu, Hanyang Chen, Xianjun Zhou, Hai-Meng Huang, Xinzhi Yang, Kai Zhu, Qian Wang, Xue Yi, Jing Zhu, Linyong Qian, Xuhong Chen, Lixin Tang, Yun Loscalzo, Joseph Yang, Yi
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;Tsinghua Univ
- 来源：CELL METABOLISM 2015
- Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs被引量：249收藏
- 作者：Chen, Xianjun Zhang, Dasheng Su, Ni Bao, Bingkun Xie, Xin Zuo, Fangting Yang, Lipeng Wang, Hui Jiang, Li Lin, Qiuning Fang, Mengyue Li, Ningfeng Hua, Xin Chen, Zhengda Bao, Chunyan Xu, Jinjin Du, Wenli Zhang, Lixin Zhao, Yuzheng Zhu, Linyong Loscalzo, Joseph Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：NATURE BIOTECHNOLOGY 2019
- 关键词：Cells - Enzyme kinetics - Fluorescence - Mammals - Cytology
- In vivo monitoring of cellular energy metabolism using SoNar, a highly responsive sensor for NAD+/NADH redox state被引量：136收藏
- 作者：Zhao, Yuzheng Wang, Aoxue Zou, Yejun Su, Ni Loscalzo, Joseph Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Harvard Med Sch
- 来源：NATURE PROTOCOLS 2016
- Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding proteins被引量：60收藏
- 作者：Liu, Renmei Yang, Jing Yao, Jing Zhao, Zhou He, Wei Su, Ni Zhang, Zeyi Zhang, Chenxia Zhang, Zhuo Cai, Haibo Zhu, Linyong Zhao, Yuzheng Quan, Shu Chen, Xianjun Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：NATURE BIOTECHNOLOGY 2022
- 关键词：Proteins - Cell culture
- Large Stokes shift fluorescent RNAs for dual-emission fluorescence and bioluminescence imaging in live cells被引量：58收藏
- 作者：Jiang, Li Xie, Xin Su, Ni Zhang, Dasheng Chen, Xianjun Xu, Xiaochen Zhang, Bibi Huang, Kaiyi Yu, Jingwei Fang, Mengyue Bao, Bingkun Zuo, Fangting Yang, Lipeng Zhang, Rui Li, Huiwen Huang, Xinyi Chen, Zhengda Zeng, Qingmei Liu, Renmei Lin, Qiuning Zhao, Yuzheng Ren, Aiming Zhu, Linyong Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Fluorescence Diag Shanghai Biotech Co Ltd;Zhejiang Univ
- 来源：NATURE METHODS 2023
- Imaging the dynamics of messenger RNA with a bright and stable green fluorescent RNA被引量：42收藏
- 作者：Zuo, Fangting Jiang, Li Su, Ni Zhang, Yaqiang Bao, Bingkun Wang, Limei Shi, Yajie Yang, Huimin Huang, Xinyi Li, Ruilong Zeng, Qingmei Chen, Zhengda Lin, Qiuning Zhuang, Yingping Zhao, Yuzheng Chen, Xianjun Zhu, Linyong Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ;East China Univ Sci & Technol;Chinese Acad Med Sci
- 来源：NATURE CHEMICAL BIOLOGY 2024
- Glucose monitoring in living cells with single fluorescent protein-based sensors被引量：36收藏
- 作者：Hu, Hanyang Wei, Yufeng Wang, Daocheng Su, Ni Chen, Xianjun Zhao, Yuzheng Liu, Guixia Yang, Yi
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol
- 来源：RSC ADVANCES 2018
- 关键词：Proteins - Escherichia coli - Cells - Cytology - Fluorescence - Metabolism - Glucose sensors
- Design of a palette of SNAP-tag mimics of fluorescent proteins and their use as cell reporters被引量：23收藏
- 作者：Zhang, Dasheng Chen, Zhengda Du, Zengmin Bao, Bingkun Su, Ni Chen, Xianjun Ge, Yihui Lin, Qiuning Yang, Lipeng Hua, Yujie Wang, Shuo Hua, Xin Zuo, Fangting Li, Ningfeng Liu, Renmei Jiang, Li Bao, Chunyan Zhao, Yuzheng Loscalzo, Joseph Yang, Yi Zhu, Linyong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Harvard Med Sch
- 来源：CELL DISCOVERY 2023
- MDH1-mediated malate-aspartate NADH shuttle maintains the activity levels of fetal liver hematopoietic stem cells被引量：20收藏
- 作者：Gu, Hao Chen, Chiqi Hao, Xiaoxin Su, Ni Huang, Dan Zou, Yejun Lin, Shu-Hai Chen, Xianjun Zheng, Denghao Liu, Ligen Yu, Zhuo Xie, Li Zhang, Yaping He, Xiaoxiao Lai, Xiaoyun Zhang, Xiaocui Chen, Guo-Qiang Zhao, Yuzheng Yang, Yi Loscalzo, Joseph Zheng, Junke
- 机构：Shanghai Jiao Tong Univ;East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Chinese Acad Sci;Harvard Med Sch
- 来源：BLOOD 2020
- Comparative pharmacophore modeling of human adenosine receptor A1 and A3 antagonists被引量：0收藏
- 作者：Xu ZheJun Cheng FeiXiong Li Jie Zhou YaDi Su Ni Li WeiHua Liu GuiXia Tang Yun
- 机构：E China Univ Sci & Technol
- 来源：SCIENCE CHINA-CHEMISTRY 2012
- 关键词：pharmacophore modeling adenosine receptors antagonists enrichment factor simulated virtual screening
