成果/Result
- Progress in the biosynthesis of bio-based PET and PEF polyester monomers被引量：76收藏
- 作者：Cui, Yanan Deng, Chen Fan, Liqiang Qiu, Yongjun Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI
- 来源：GREEN CHEMISTRY 2023
- 关键词：Biochemistry - Biomass - Biosynthesis - Conservation - Cost effectiveness - Enzymes - Ethylene - Monomers - Natural resources - Petroleum industry - Plastic bottles - Polyethylene terephthalates
- Bioconversion of chitin into chitin oligosaccharides using a novel chitinase with high chitin-binding capacity被引量：26收藏
- 作者：Zhao, Qiong Fan, Liqiang Deng, Chen Ma, Chunyu Zhang, Chunyue Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF BIOLOGICAL MACROMOLECULES 2023
- 关键词：Chitinase Chitin oligosaccharides Purification Molecular simulation Biodegradation
- Advances in green bioproduction of marine and glycosaminoglycan oligosaccharides被引量：26收藏
- 作者：Deng, Chen Zhao, Mengxuan Zhao, Qiong Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CARBOHYDRATE POLYMERS 2023
- 关键词：Functional oligosaccharide Activity and application Green biosynthesis Enzyme engineering Synthetic biology
- De novo biosynthesis of 2′-fucosyllactose in engineered Pichia pastoris被引量：18收藏
- 作者：Qian, Difan Zhang, Chunyue Deng, Chen Zhou, Mian Fan, Liqiang Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Changzheng Hosp;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI
- 来源：BIOTECHNOLOGY LETTERS 2023
- 关键词：Biosynthesis 2 '-Fucosyllactose Human milk oligosaccharides Pichia pastoris
- Optogenetic control of Corynebacterium glutamicum gene expression被引量：8收藏
- 作者：Deng, Chen Xin, Ruijie Li, Xingjian Zhang, Jie Fan, Liqiang Qiu, Yongjun Zhao, Liming
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：NUCLEIC ACIDS RESEARCH 2024
- Combinatorial metabolic engineering of Escherichia coli for de novo production of structurally defined and homogeneous Amino oligosaccharides被引量：6收藏
- 作者：Shi, Jinqi Deng, Chen Zhang, Chunyue Quan, Shu Fan, Liqiang Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Changzheng Hosp;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI;East China Univ Sci & Technol
- 来源：SYNTHETIC AND SYSTEMS BIOTECHNOLOGY 2024
- 关键词：Amino oligosaccharides Chitin oligosaccharides Metabolic engineering Fed-batch cultivation bioproduction
- De novo 2′-fucosyllactose bioproduction through modular engineering of a novel Escherichia coli K12-derived strain被引量：5收藏
- 作者：Ma, Chunyu Zhang, Chunyue Fan, Liqiang Deng, Chen Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI;Shanghai Changzheng Hosp
- 来源：FOOD BIOENGINEERING 2023
- 关键词：2 '-fucosyllactose Escherichia coli metabolic engineering alpha-1,2-fucosyltransferase
- Isolation and Identification of a Novel Chitinilyticum sp.C8: Unleashing the Potential for Chitin Oligosaccharides Production被引量：1收藏
- 作者：Zhao, Qiong Fan, Liqiang Cui, Yanan Zhao, Mengxuan Deng, Chen Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI;East China Univ Sci & Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2025
- 关键词：chitinase chitin oligosaccharides bacterialfermentation biodegradation
Chitinilyticum sp.C8
- Novel iterative genome mining and engineering of a bifunctional KvVDH enable selective production of furan carboxylic acids from high-concentration 5-hydroxymethylfurfural被引量：0收藏
- 作者：Cui, Yanan Zhang, Jie Xing, Xijun Zhang, Hanwen Chen, Yutong Fan, Liqiang Li, Xu Qiu, Yongjun Deng, Chen Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI;East China Univ Sci & Technol
- 来源：GREEN CHEMISTRY 2026
- 关键词：Biosynthesis - Carboxylic acids - Catalysis - Catalyst activity - Computational efficiency - Conformations - Enzymes - Genes - Genome - Hydrogen bonds - Iterative methods - Screening
- 谷氨酸棒状杆菌合成硫酸软骨素被引量：0收藏
- 作者：李行健 邓琛 赵黎明
- 机构：华东理工大学生物工程学院生物反应器工程国家重点实验室
- 来源：《中国食品科学技术学会第二十一届年会》 2024
- 关键词：硫酸软骨素A 谷氨酸棒杆菌 合成生物学
- 摘要：硫酸软骨素(chondroitin sulfate,CS)是一类磺酸化的糖胺聚糖,存在于人和动物的结缔组织中,可以作为保健食品或药品,用于防治心脑血管疾病、骨关节炎等。当前商品化的硫酸软骨素主要来源于动物软骨组织提取,但...
- Corynebacterium glutamicum for Microbial Production of Chitin Oligosaccharides Using Modular Engineering被引量：0收藏
- 作者：Deng, Chen Xin, Ruijie Li, Xingjian Fan, Liqiang Qiu, Yongjun Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI;East China Univ Sci & Technol
- 来源：FOOD BIOENGINEERING 2025
- 关键词：chitin oligosaccharides
Corynebacterium glutamicum metabolic engineering synthetic biology UDP-sugar donor
- 壳聚糖酶的虚拟筛选与优化被引量：0收藏
- 作者：赵梦琪 邓琛 李旭 范立强 邱勇隽 赵黎明
- 机构：华东理工大学生物反应器工程国家重点实验室
- 来源：《中国食品科学技术学会第二十二届年会》 2025
- 关键词：壳寡糖 壳聚糖酶 虚拟筛选 合成生物学
- 摘要：壳寡糖(Chitooligosaccharides,COS)是壳聚糖降解后产生的功能性低聚糖,具备良好的生物相容性、抗菌性、免疫调节及促植物生长等特性,在医药、农业和食品工业中具有广阔的应用前景。目前,壳寡糖的酶法生产主...
- Combinatorial metabolic engineering of Escherichia coli for de novo production of structurally defined and homogeneous Amino oligosaccharides被引量：0收藏
- 作者：Jinqi Shi Chen Deng Chunyue Zhang Shu Quan Liqiang Fan Liming Zhao
- 机构：State Key Laboratory of Bioreactor Engineering;Organ Transplant Center;Shanghai Collaborative Innovation Center for Biomanufacturing Technology(SCICBT)
- 来源：合成和系统生物技术(英文) 2024
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- Multi-dimensional metabolic engineering and enzyme engineering in Escherichia coli for highly efficient biosynthesis of 2,5-furandicarboxylic acid被引量：0收藏
- 作者：Cui, Yanan Zhang, Peiyi Miao, Renjie Zhao, Mengqi Fan, Liqiang Li, Xu Qiu, Yongjun Deng, Chen Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI;East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2026
- 关键词：5-Hydroxymethylfurfural 5-Furandicarboxylic acid Metabolic engineering Cofactors engineering Transporter engineering Fermentation
- Enhanced heparosan biosynthesis in Corynebacterium glutamicum by systematic metabolic engineering and translation-level fine-tuning被引量：0收藏
- 作者：Zhang, Jie Cui, Yanan Zhang, Peiyi Zhao, Mengqi Fan, Liqiang Li, Xu Deng, Chen Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI
- 来源：BIORESOURCES AND BIOPROCESSING 2026
- 关键词：Heparosan
Corynebacterium glutamicum Systematic metabolic engineering Translation-level fine-tuning Fed-batch fermentation
- Integrated surface display and atp regeneration for efficient butyrolactam biosynthesis in Escherichia coli被引量：0收藏
- 作者：Cui, Xiangcao Liu, Xiaosen Zhang, Huiling Zhou, Kun Tang, Cunzhuo Deng, Chen Li, Xu Qiu, Yongjun Fan, Liqiang Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：BIOCHEMICAL ENGINEERING JOURNAL 2026
- 关键词：Butyrolactam Surface display beta-alanine CoA transferase ATP regeneration Biocatalysis
