成果/Result
- Harnessing the intracellular triacylglycerols for titer improvement of polyketides in Streptomyces被引量：143收藏
- 作者：Wang, Weishan Li, Shanshan Li, Zilong Zhang, Jingyu Fan, Keqiang Tan, Gaoyi Ai, Guomin Lam, Sin Man Shui, Guanghou Yang, Zhiheng Lu, Hongzhong Jin, Pinjiao Li, Yihong Chen, Xiangyin Xia, Xuekui Liu, Xueting Dannelly, H. Kathleen Yang, Chen Yang, Yi Zhang, Siliang Alterovitz, Gil Xiang, Wensheng Zhang, Lixin
- 机构：Chinese Acad Sci;East China Univ Sci & Technol;Chinese Acad Agr Sci;Chinese Acad Sci;Qilu Univ Technol
- 来源：NATURE BIOTECHNOLOGY 2020
- 关键词：Ketones - Metabolism - Biochemistry - Bacteria - Metabolites - Glycerol
- Berberine reverses multidrug resistance in Candida albicans by hijacking the drug efflux pump Mdr1p被引量：58收藏
- 作者：Tong, Yaojun Zhang, Jingyu Sun, Nuo Wang, Xiang-Ming Wei, Qi Zhang, Yu Huang, Ren Pu, Yingying Dai, Huanqin Ren, Biao Pei, Gang Song, Fuhang Zhu, Guoliang Wang, Xinye Xia, Xuekui Chen, Xiangyin Jiang, Lan Wang, Shenlin Ouyang, Liming Xie, Ning Zhang, Buchang Jiang, Yuanying Liu, Xueting Calderone, Richard Bai, Fan Zhang, Lixin Alterovitz, Gil
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;Peking Univ;Georgetown Univ
- 来源：SCIENCE BULLETIN 2021
- 关键词：Candida albicans Berberine Multidrug-resistance Drug excretion transporter Mitochondria
- Chrysomycin A Derivatives for the Treatment of Multi-Drug-Resistant Tuberculosis被引量：54收藏
- 作者：Wu, Fan Zhang, Jing Song, Fuhang Wang, Sanshan Guo, Hui Wei, Qi Dai, Huanqin Chen, Xiangyin Xia, Xuekui Liu, Xueting Zhang, Lixin Yu, Jin-Quan Lei, Xiaoguang
- 机构：Peking Univ;Peking Univ;Chinese Acad Sci;East China Univ Sci & Technol;Qilu Univ Technol
- 来源：ACS CENTRAL SCIENCE 2020
- Dual-function injectable fibrin gel incorporated with sulfated chitosan nanoparticles for rhBMP-2-induced bone regeneration被引量：25收藏
- 作者：Chen, Xinye Wang, Shuang Zhang, Xiaohui Yu, Yuanman Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：APPLIED MATERIALS TODAY 2022
- 关键词：BMP-2 Sulfated chitosan Immunomodulation Bone regeneration
- Recent advances in biotechnology for marine enzymes and molecules被引量：21收藏
- 作者：Zhang, Jingyu Jiang, Lan Chen, Xiangyin Lv, Kangjie Basiony, Mostafa Zhu, Guoliang Karthik, Loganathan Ouyang, Liming Zhang, Lixin Liu, Xueting
- 机构：East China Univ Sci & Technol;Salem Microbes Private Ltd
- 来源：CURRENT OPINION IN BIOTECHNOLOGY 2021
- 关键词：Synthetic biology - Ecosystems - Metabolic engineering - Marine applications - Molecules
- Genome-guided investigation of anti-inflammatory sesterterpenoids with 5-15 trans-fused ring system from phytopathogenic fungi被引量：15收藏
- 作者：Jiang, Lan Zhu, Guoliang Han, Jianying Hou, Chengjian Zhang, Xue Wang, Zhixin Yuan, Weize Lv, Kangjie Cong, Zhanren Wang, Xinye Chen, Xiangyin Karthik, Loganathan Yang, Huanting Wang, Xuyuan Tan, Gaoyi Liu, Guang Zhao, Liya Xia, Xuekui Liu, Xiangyang Gao, Shushan Ma, Lei Liu, Mei Ren, Biao Dai, Huanqin Quinn, Ronald J. Hsiang, Tom Zhang, Jingyu Zhang, Lixin Liu, Xueting
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;Griffith Univ;Qilu Univ Technol;T3 Biosci LLC
- 来源：APPLIED MICROBIOLOGY AND BIOTECHNOLOGY 2021
- 关键词：Fungi Bifunctional terpene synthases Terpenoids Anti-inflammatory
- Regio- and stereo-selective amination of fatty acids to d-amino acids by a three-step one-pot cascade被引量：13收藏
- 作者：Yu, Xing Chen, Xin-Yi Yu, Hui-Lei Xu, Jian-He Zhang, Zhi-Jun
- 机构：East China Univ Sci & Technol
- 来源：GREEN CHEMISTRY 2023
- 关键词：Amination - Amines - Amino acids - Recycling - Stereochemistry
- Dual-Modular Hydrogel Microparticles with Precision-Modulation of Inflammatory Microenvironment Dictate Full-Thickness Cartilage Regeneration for Osteoarthritis Repair被引量：4收藏
- 作者：Chen, Xinye Yu, Yuanman He, Zirui Pan, Lina Wang, Jing Liu, Changsheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ADVANCED SCIENCE 2025
- 关键词：cartilage regeneration hydrogel microparticles inflammatory modulation osteoarthritis
- Lactiplantibacillus plantarum X7022 ameliorates loperamide-induced constipation and modulates gut microbiota in mice被引量：3收藏
- 作者：Chen, Xingye Liu, Guang Zhao, Li Du, Lei Xie, Jingli Wei, Dongzhi
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg SCICB
- 来源：FOOD BIOENGINEERING 2022
- 关键词：constipation gut microbiota Lactiplantibacillus plantarum X7022
- Characterization of Streptomyces sp. LS462 with high productivity of echinomycin, a potent antituberculosis and synergistic antifungal antibiotic被引量：0收藏
- 作者：Chen, Caixia Chen, Xiangyin Ren, Biao Guo, Hui Abdel-Mageed, Wael M. Liu, Xueting Song, Fuhang Zhang, Lixin
- 机构：Chinese Acad Sci;East China Univ Sci & Technol;Sichuan Univ;Chinese Acad Sci;King Saud Univ
- 来源：JOURNAL OF INDUSTRIAL MICROBIOLOGY & BIOTECHNOLOGY 2021
- 关键词：Streptomyces fuscichromogenes Echinomycin Antituberculosis Synergistic antifungal activity Posaconazole
- Efficient Synthesis of ErgothionEIne in Escherichia coli Through Identification of Bacterial-Type Egt1 and Self-Assemble of Pathway Enzymes被引量：0收藏
- 作者：Chen, Xin-Yi Yan, Shuai Li, Hang-Cheng Liu, Hai-Ping Yu, Hui-Lei Xu, Jian-He Zhang, Zhi-Jun
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：BIOTECHNOLOGY AND BIOENGINEERING 2026
- 关键词：biosynthesis ergothionEIne fermentation genome mining protEIn self-assemble
- Enantiocomplementary synthesis of chiral 2,3-dihydroxy aryl ketones via ThDP-dependent enzymatic catalysis被引量：0收藏
- 作者：Li, Dan Zhu, Zheng Chen, Xiaoyu Chen, Xuesi Ouyang, Liming Li, Huangong Zhang, Lixin Xie, Yongtao
- 机构：East China Univ Sci & Technol;Chinese Acad Sci
- 来源：GREEN CHEMISTRY 2026
- 关键词：Biochemical engineering - Catalysis - Stereochemistry - Synthesis (chemical)
- Publisher Correction: Harnessing the intracellular triacylglycerols for titer improvement of polyketides in Streptomyces (Nature Biotechnology, (2020), 38, 1, (76-83), 10.1038/s41587-019-0335-4)被引量：-1收藏
- 作者：Wang, Weishan Li, Shanshan Li, Zilong Zhang, Jingyu Fan, Keqiang Tan, Gaoyi Ai, Guomin Lam, Sin Man Shui, Guanghou Yang, Zhiheng Lu, Hongzhong Jin, Pinjiao Li, Yihong Chen, Xiangyin Xia, Xuekui Liu, Xueting Dannelly, H. Kathleen Yang, Chen Yang, Yi Zhang, Siliang Alterovitz, Gil Xiang, Wensheng Zhang, Lixin
- 机构： State Key Laboratory of Microbial Resources; State Key Laboratory of Bioreactor Engineering; State Key Laboratory for Biology of Plant Diseases and Insect Pests; State Key Laboratory of Molecular Developmental Biology; Key Biosensor Laboratory of Shandong Province
- 来源：Nature Biotechnology 2020
