成果/Result
- Insight into the effect of cocrystal polymorphism / stoichiomorphism on thermodynamic and photoluminescence properties: a case study被引量：45收藏
- 作者：Han, Xianyang Yin, Yu Zhu, Fan Yao, Yichen Hong, Minghuang Qi, Minghui Zhu, Bin Ren, Guobin
- 机构： Laboratory of Pharmaceutical Crystal Engineering & Technology; State Key Laboratory of Bioreactor Engineering
- 来源：SSRN 2025
- 关键词：Crystal structure - Fluorescence - Fluorescence spectroscopy - Optical properties - Phase transitions - Photoluminescence - Polymorphism - Single crystals - Thermoanalysis - X ray diffraction
- Isostructural Levamisole Hydrochloride Ionic Cocrystal Solvates: High Z″ with a Low Melting Point被引量：40收藏
- 作者：Yao, Yi-Chen Jin, Zhe Hong, Minghuang Zhu, Bin Ren, Guo-Bin Qi, Ming-Hui
- 机构： Laboratory of Pharmaceutical Crystal Engineering & Technology
- 来源：Crystal Growth and Design 2024
- 关键词：Melting point - Single crystals - Surface analysis - Thermoanalysis
- Solid-State Characterization and Insight into Transformations and Stability of Apatinib Mesylate Solvates被引量：32收藏
- 作者：Zhu, Bin Zhang, Qi Ren, Guobin Mei, Xuefeng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：CRYSTAL GROWTH & DESIGN 2017
- 关键词：Differential scanning calorimetry - Single crystals - Thermogravimetric analysis - Quality control
- Slow-Release Drug-Drug Cocrystals of Oxaliplatin with Flavonoids: Delaying Hydrolysis and Reducing Toxicity被引量：31收藏
- 作者：Yin, He-Mei Wu, Nan Zhou, Bi-Jian Hong, Ming-Huang Zhu, Bin Qi, Ming-Hui Ren, Guo-Bin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2021
- 关键词：Single crystals - Cancer cells - Controlled drug delivery - Fourier transform infrared spectroscopy - Dissolution - Targeted drug delivery - Cells - Flavonoids - X ray diffraction - Hydrogen bonds - Thermoanalysis - Toxicity - Cytology
- Stable Cocrystals and Salts of the Antineoplastic Drug Apatinib with Improved Solubility in Aqueous Solution被引量：29收藏
- 作者：Zhu, Bin Wang, Jian-Rong Zhang, Qi Li, Meiqi Guo, Chunyang Ren, Guobin Mei, Xuefeng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;Univ Chinese Acad Sci
- 来源：CRYSTAL GROWTH & DESIGN 2018
- 关键词：Infrared spectroscopy - Single crystals - Solubility - X ray diffraction - Cell proliferation - Drug delivery - Endothelial cells - Amino acids - Differential scanning calorimetry
- Cocrystals of Oxymatrine: Reducing Hygroscopicity and Affecting the Dissolution Rate被引量：25收藏
- 作者：Qi, Ming-Hui Li, Heng Zhu, Bin Hong, Minghuang Ren, Guo-Bin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2021
- 关键词：Dissolution - Hydrogen bonds - Metabolism
- Fine-Tuning the Colors of Natural Pigment Emodin with Superior Stability through Cocrystal Engineering被引量：24收藏
- 作者：Li, Meiqi Zhang, Zhen Zhang, Qi Peng, Bo Zhu, Bin Wang, Jian-rong Liu, Liyu Mei, Xuefeng
- 机构：Chinese Acad Sci;Univ Chinese Acad Sci;Nanchang Univ;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2018
- 关键词：Chemical stability - Charge transfer - Chemical modification
- Polymorphs and Hydrates of Apatinib Mesylate: Insight into the Crystal Structures, Properties, and Phase Transformations被引量：22收藏
- 作者：Zhu, Bin Wang, Jian-Rong Ren, Guobin Mei, Xuefeng
- 机构：East China Univ Sci & Technol;Chinese Acad Sci
- 来源：CRYSTAL GROWTH & DESIGN 2016
- 关键词：Differential scanning calorimetry - Single crystals - Thermogravimetric analysis - Hydrates - Phase transitions - Fourier transform infrared spectroscopy - X ray diffraction
- Strategy for Efficient Discovery of Cocrystals via a Network-Based Recommendation Model被引量：22收藏
- 作者：Zheng, Lulu Zhu, Bin Wu, Zengrui Fang, Xiaoxue Hong, Minghuang Liu, Guixia Li, Weihua Ren, Guobin Tang, Yun
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2020
- Study of Crystal Structures, Properties, and Form Transformations among a Polymorph, Hydrates, and Solvates of Apatinib被引量：22收藏
- 作者：Zhu, Bin Fang, Xiaoxue Zhang, Qi Mei, Xuefeng Ren, Guobin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：CRYSTAL GROWTH & DESIGN 2019
- 关键词：Differential scanning calorimetry - X ray diffraction - Cell proliferation - Hydration - Endothelial cells - Thermogravimetric analysis - Amino acids - Single crystals
- Insight into the Formation of Cocrystals of Flavonoids and 4,4′-Vinylenedipyridine: Heteromolecular Hydrogen Bonds, Molar Ratio, and Structural Analysis被引量：19收藏
- 作者：Zhang, Yanhong Zhu, Bin Ji, Wei-Jie Guo, Chun-Yang Hong, Minghuang Qi, Ming-Hui Ren, Guo-Bin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2021
- 关键词：Hydrogen bonds - Single crystals - Molar ratio
- Cocrystals of flavonoids with 4,4′-ethylenebispyridine: Crystal structures analysis, dissolution behavior, and anti-tumor activity被引量：16收藏
- 作者：Zhang, Yanhong Yang, Rui Yin, He-Mei Zhou, Bijian Hong, Minghuang Zhu, Bin Qi, Ming-Hui Ren, Guo-Bin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF MOLECULAR STRUCTURE 2022
- 关键词：Tumors - Cancer cells - Single crystals - Dissolution
- Study of Cycloxaprid Co-crystals: Characterization, Theory Calculation, Solubility, and Stability被引量：12收藏
- 作者：Li, Mengnan Wang, Jinling Xu, Xiaoyong Ren, Guobin Zhu, Bin Hong, Minghuang Li, Zhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2022
- 关键词：Chemical stability - Differential scanning calorimetry - Fourier transform infrared spectroscopy - Molecular orbitals - Nuclear magnetic resonance spectroscopy - Single crystals - Thermogravimetric analysis - X ray diffraction
- SMINBR: An Integrated Network and Chemoinformatics Tool Specialized for Prediction of Two-Component Crystal Formation被引量：11收藏
- 作者：Zheng, Lulu Zhu, Bin Wu, Zengrui Liang, Fang Hong, Minghuang Liu, Guixia Li, Weihua Ren, Guobin Tang, Yun
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF CHEMICAL INFORMATION AND MODELING 2021
- 关键词：Molecular interactions - Molecular structure - Crystals - Physicochemical properties
- Colorful Prothionamide Salt Forms with Enhancement in Water Solubility and Dissolution Behavior被引量：9收藏
- 作者：Ji, Wei-Jie Jiang, Jun-Yi Hong, Minghuang Zhu, Bin Ren, Guo-Bin Qi, Ming-Hui
- 机构：East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2023
- 关键词：Dissolution - Drug delivery - Free energy - Molecular orbitals - Naphthalene - Salts - Solubility
- Novel Salts of the Atypical Antipsychotic Drug Lurasidone with Improved Solubility and Bioavailability被引量：9收藏
- 作者：Guo, Chunyang Wang, Yuan Xie, Junyi Zhu, Bin Qi, Ming-Hui Hong, Minghuang Ren, Guo-Bin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2023
- 关键词：Biochemistry - Drug delivery - Single crystals - Solubility - Thermoanalysis - X ray diffraction
- Crystal structure and physical stability of ginsenoside compound-K solvates被引量：6收藏
- 作者：Chen, Jinyao Zhu, Wenming Ji, Weijie Zhu, Bin Guo, Chunyang Qi, Minghui Ren, Guobin
- 机构：East China Univ Sci & Technol;Zhejiang Hisun Pharmaceut Co
- 来源：CRYSTENGCOMM 2019
- 关键词：Hydrogen bonds - X ray diffraction - Organic solvents - Thermogravimetric analysis - Single crystals - Stability - Differential scanning calorimetry - Molecules - Ethanol
- Intersected Bicyclic N-Confused Corrole Dimers with Tunable Aromaticity and Topological Chirality被引量：5收藏
- 作者：Huang, Yanping Zhu, Bin Li, Shijun Baryshnikov, Glib Wang, Hailong Li, Chengjie Agren, Hans Jiang, Jianzhuang Xie, Yongshu Li, Qizhao
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Normal Univ;Linkoping Univ;Univ Sci & Technol Beijing
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2025
- 关键词：Aromatic compounds - Aromatization - Atoms - Copper - Copper compounds - Cyclization - Indium compounds - Metal ions - Stereochemistry - Synthesis (chemical) - Topology
- Enhancement of solubility and dissolution rate of dipyridamole by salifying: Preparation, characterization, and theoretical calculation被引量：5收藏
- 作者：Yi, Dongxu Dong, Yuhang Yao, Yichen Hong, Minghuang Zhu, Bin Ren, Guo-Bin Qi, Ming-Hui
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF MOLECULAR STRUCTURE 2024
- 关键词：Dipyridamole Salt Solubility Fluorescence
- Conformation, virtual cocrystal screening, synthesis and determination of dipyridamole被引量：5收藏
- 作者：Yi, Dongxu Dong, Yuhang Qi, Minghui Hong, Minghung Zhu, Bin Ren, Guobin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF MOLECULAR STRUCTURE 2024
- 关键词：Dipyridamole Conformation Virtual cocrystal screening
- NPtagM: A Tailoring Enzyme Genome Mining Toolkit and Its Application in Terpenoid P450s from Phytopathogenic Fungi被引量：3收藏
- 作者：Cong, Zhanren Mukoma, Njeru Joe Yin, Qiang Zhu, Bin She, Lingwei Hsiang, Tom Zhang, Lixin Jiang, Lan Liu, Xueting
- 机构：East China Univ Sci Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Beijing Inst Technol;Univ Guelph
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2024
- 关键词：NPtagM tailoring enzyme genome mining terpenoids cytochrome P450 phytopathogenic fungi
- Insight into the Structure and Property Diversity of Four Nicorandil Oxalate Salt Polymorphs Based on Experiments and Quantum Chemistry Study被引量：3收藏
- 作者：Wang, Qinglin Guo, Chunyang Qi, Ming-Hui Zhu, Bin Ren, Guo-Bin Hong, Minghuang
- 机构：East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2024
- 关键词：Binding energy - Crystal structure - Dissolution - Nickel compounds - Oxalic acid - Quantum chemistry - Single crystals - Solvents - Structural properties
- Solubility Measurement and Dynamic Simulation Analysis of the Brivaracetam Form A in 12 Pure Solvents被引量：3收藏
- 作者：Wu, Yue Shao, Jia-Hui Zhu, Bin Hong, Minghuang Ren, Guo-Bin Qi, Ming-Hui
- 机构：Shanghai Frontiers Sci Ctr Optogenet Tech Cell Met;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF CHEMICAL AND ENGINEERING DATA 2025
- 关键词：Hydrogen bonds - Molecular dynamics - Solubility
- Preparation, characterization, and crystal structures of novel sophocarpine salts with improvements on stability and solubility被引量：2收藏
- 作者：Wang, Yuan Qian, Yi-Hui Hong, Ming-Huang Zhu, Bin Ren, Guo-Bin Qi, Ming -Hui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF MOLECULAR STRUCTURE 2023
- 关键词：Crystal engineering Crystal structure Stability Thermal properties Sophocarpine
- Strategy to Regulate the Stability and Reduction Rate of Oxaliplatin-Based Pt(IV) Complexes: Cocrystallization被引量：1收藏
- 作者：Zhu, Bin Guo, Mei Yao, Yi-Chen Yao, Yu-Qian Hong, Minghuang Qi, Ming-Hui Ren, Guo-Bin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2023
- 关键词：Benzoic acid - Oxalic acid - Platinum compounds - Single crystals - Synthesis (chemical) - Thermoanalysis - X ray diffraction
- Solvatochromism and mechanochromism observed in a triphenylamine derivative被引量：1收藏
- 作者：Guo, Chunyang Zhang, Qi Zhu, Bingqing Zhu, Bin Zhou, Weiqun Ren, Guobin Mei, Xuefeng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;Soochow Univ
- 来源：ACTA CRYSTALLOGRAPHICA SECTION B-STRUCTURAL SCIENCE CRYSTAL ENGINEERING AND MATERIALS 2019
- 关键词：donor-pi-acceptor fluorescent dye triphenylamine (TPA) derivative intramolecular charge transfer intermolecular charge transfer aggregation-induced emission
- Exploring New Solid Forms of Antirheumatic Drug Hydroxychloroquine: Novel Salts with Sustained-Release Performance被引量：1收藏
- 作者：Ji, Wei-Jie Wu, Yue Hong, Minghuang Zhu, Bin Ren, Guo-Bin Qi, Ming-Hui
- 机构：East China Univ Sci & Technol
- 来源：CRYSTAL RESEARCH AND TECHNOLOGY 2024
- 关键词：hydroxychloroquine hygroscopicity salification sustained-release
- A novel anion replaced gemini surfactant: Investigation on the primary interaction between gemini surfactant and BSA被引量：1收藏
- 作者：Jin, Yuhao Wu, Qi Yang, Ke Xu, Qianlin Bian, Yizhen Qi, Ming-Hui Zhu, Bin Ren, Guo-Bin Hong, Minghuang
- 机构：East China Univ Sci & Technol
- 来源：COLLOIDS AND SURFACES B-BIOINTERFACES 2025
- 关键词：Gemini surfactant Bovine serum albumin Electrostatic interaction Hydrophobic interaction
- Study on Triflumezopyrim Solid Forms: Crystal Structure Analysis and Suspension Concentrate Application Insights被引量：1收藏
- 作者：Wang, Mingxia Li, Xiaoyan Zhu, Bin Ren, Guo-Bin Qi, Ming-Hui Li, Zhong Xu, Xiaoyong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2024
- 关键词：Hydration - Insect control - Polymorphism - Suspensions (components) - Suspensions (fluids) - Thermolysis - X ray diffraction analysis
- Cocry-pred: A Dynamic Resource Propagation Method for Cocrystal Prediction被引量：1收藏
- 作者：Song, Wenxiang Peng, Ren Yu, Hongbo Zhan, Meiling Liu, Guixia Li, Weihua Ren, Guobin Zhu, Bin Tang, Yun
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF CHEMICAL INFORMATION AND MODELING 2025
