成果/Result
- Visualizing RNA dynamics in live cells with bright and stable fluorescent RNAs被引量：249收藏
- 作者：Chen, Xianjun Zhang, Dasheng Su, Ni Bao, Bingkun Xie, Xin Zuo, Fangting Yang, Lipeng Wang, Hui Jiang, Li Lin, Qiuning Fang, Mengyue Li, Ningfeng Hua, Xin Chen, Zhengda Bao, Chunyan Xu, Jinjin Du, Wenli Zhang, Lixin Zhao, Yuzheng Zhu, Linyong Loscalzo, Joseph Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：NATURE BIOTECHNOLOGY 2019
- 关键词：Cells - Enzyme kinetics - Fluorescence - Mammals - Cytology
- Optogenetic control of RNA function and metabolism using engineered light-switchable RNA-binding protEIns被引量：60收藏
- 作者：Liu, Renmei Yang, Jing Yao, Jing Zhao, Zhou He, Wei Su, Ni Zhang, Zeyi Zhang, Chenxia Zhang, Zhuo Cai, Haibo Zhu, Linyong Zhao, Yuzheng Quan, Shu Chen, Xianjun Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：NATURE BIOTECHNOLOGY 2022
- 关键词：ProtEIns - Cell culture
- Glucose monitoring in living cells with single fluorescent protEIn-based sensors被引量：36收藏
- 作者：Hu, Hanyang Wei, Yufeng Wang, Daocheng Su, Ni Chen, Xianjun Zhao, Yuzheng Liu, Guixia Yang, Yi
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol
- 来源：RSC ADVANCES 2018
- 关键词：ProtEIns - Escherichia coli - Cells - Cytology - Fluorescence - Metabolism - Glucose sensors
- Spatiotemporally controllable diphtheria toxin expression using a light-switchable transgene system combining multifunctional nanoparticle delivery system for targeted melanoma therapy被引量：28收藏
- 作者：He, Muye Wang, Yan Chen, Xianjun Zhao, Yuzheng Lou, Kaiyan Wang, Yujie Huang, Lei Hou, Xinyu Xu, Jiajun Cai, Xiaoran Cheng, Yi Lan, Minbo Yang, Yi Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF CONTROLLED RELEASE 2020
- 关键词：Light-switchable gene expression Diphtheria toxin Melanoma Nanoparticle delivery system
- Imaging intracellular metabolite and protEIn changes in live mammalian cells with bright fluorescent RNA-based genetically encoded sensors被引量：17收藏
- 作者：Fang, Mengyue Li, Huiwen Xie, Xin Wang, Hui Jiang, Ying Li, Tianyu Zhang, Bibi Jiang, Xin Cao, Yueyang Zhang, Rui Zhang, Dasheng Zhao, Yuzheng Zhu, Linyong Chen, Xianjun Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Jiao Tong Univ
- 来源：BIOSENSORS & BIOELECTRONICS 2023
- 关键词：Genetically encoded sensor Fluorogenic RNA aptamer Pepper Metabolite and protEIn dynamics
- Spatiotemporally controlled Pseudomonas exotoxin transgene system combined with multifunctional nanoparticles for breast cancer antimetastatic therapy被引量：16收藏
- 作者：Cheng, Yi Zou, Jiafeng He, Muye Hou, Xinyu Wang, Hongtao Xu, Jiajun Yuan, Zeting Lan, Minbo Yang, Yi Chen, Xianjun Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：JOURNAL OF CONTROLLED RELEASE 2024
- 关键词：Spatiotemporally controlled gene expression cancer -associated fibroblasts Multifunctional nanoparticles Pseudomonas exotoxin A Antimetastasis therapy Breast cancer
- Sequential Rocket-Mode Bioactivating Ticagrelor Prodrug Nanoplatform Combining Light-Switchable Diphtherin Transgene System for Breast Cancer Metastasis Inhibition被引量：7收藏
- 作者：Zou, Jiafeng Sun, Rui He, Muye Chen, You Cheng, Yi Xia, Chuanhe Ma, Ying Zheng, Shulei Fu, Xiuzhi Yuan, Zeting Lan, Minbo Lou, Kaiyan Chen, Xianjun Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Univ Tradit Chinese Med;East China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2023
- 关键词：breast cancer metastasis LightOn system ticagrelor cell membrane fusionliposomes sequential bioactivatingprodrug
- Spatiotemporally controllable diphtherin transgene system and neoantigen immunotherapy被引量：7收藏
- 作者：He, Muye Sun, Yuji Cheng, Yi Wang, Jie Zhang, Miao Sun, Rui Hou, Xinyu Xu, Jiajun He, Hai Wang, Hongtao Yuan, Zeting Lan, Minbo Zhao, Yuzheng Yang, Yi Chen, Xianjun Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Univ Tradit Chinese Med;East China Univ Sci & Technol;Chinese Acad Med Sci
- 来源：JOURNAL OF CONTROLLED RELEASE 2023
- 关键词：Light-switchable diphtherin gene expression Melanoma Immunotherapy Neoantigen Nanoparticle delivery system
- Development of Acrylamide-Based Rapid and Multicolor Fluorogenic Probes for High Signal-to-Noise Live Cell Imaging被引量：6收藏
- 作者：Zhang, Dasheng Liu, Renmei Bao, Chunyan Zhang, Chenxia Yang, Lipeng Deng, Lei Bao, Bingkun Yang, Jing Chen, Xianjun Lin, Qiuning Yang, Yi Zhu, Linyong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOCONJUGATE CHEMISTRY 2019
- 关键词：Amides - Cells - ProtEIns - Signal to noise ratio - Ligands - Cytology
- Bright and Stable Cyan Fluorescent RNA Enables Multicolor RNA Imaging in Live Escherichia coli被引量：3收藏
- 作者：Jiang, Li Zuo, Fangting Pan, Yuanyuan Li, Ruilong Shi, Yajie Huang, Xinyi Zhang, Dasheng Zhuang, Yingping Zhao, Yuzheng Lin, Qiuning Yang, Yi Zhu, Linyong Chen, Xianjun
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Med Sci
- 来源：SMALL 2025
- 关键词：bioorthogonality cyan fluorescent RNA fluorophore RNA aptamer RNA imaging
- Synthetic yeast-bacterium consortium enables co-inducible relayed synthesis of chemicals被引量：0收藏
- 作者：Xu, Mingqiang Yu, Jiahui Chen, Xinjie Li, Xie Guo, Yan Qian, Zhilan Liu, Qi Ren, Yanna Lu, Jian Chen, Xianjun Yang, Yi Cai, Menghao
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：METABOLIC ENGINEERING 2026
- 关键词：Synthetic consortiums Co-inducible Quorum sensing Optogenetics Komagataella phaffii Escherichia coli
- A GeneralStrategy for Developing Si-Rhodamine-BasedFluorogenic Dyes for Advanced Bioimaging and Biosensing被引量：0收藏
- 作者：Chen, Zhengda Shi, Yajie Jiang, Li Yin, Yuxin Yang, Lipeng Huang, Xinyi Jiang, Ling Guo, Wenjie Liu, Xiaoyu Fu, Rong Liu, Huining Bao, Bingkun Lin, Qiuning Zhao, Yuzheng Chen, Xianjun Yang, Yi Zhu, Linyong
- 机构：Shanghai Jiao Tong Univ;East China Univ Sci & Technol;Frontiers Med Ctr
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2026
- 关键词：Bioimaging - Dyes - Fluorescence imaging - Silicon compounds - Stimulated emission
