成果/Result
- Clodronate-loaded liposomal and fibroblast-derived exosomal hybrid system for enhanced drug delivery to pulmonary fibrosis被引量：157收藏
- 作者：Sun, Lingna Fan, Mingrui Huang, Dong Li, Bingqin Xu, Ruoting Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOMATERIALS 2021
- 关键词：Pulmonary fibrotic therapy Exosomes Liposomes Macrophages depletion Fibrosis penetration
- Analyte Regeneration Fluorescent Probes for Formaldehyde Enabled by Regiospecific Formaldehyde-Induced Intramolecularity被引量：72收藏
- 作者：Xu, Hang Xu, Huan Ma, Shengnan Chen, Xiani Huang, Lixian Chen, Junwei Gao, Feng Wang, Rui Lou, Kaiyan Wang, Wei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Univ Arizona;Univ Arizona
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2018
- 关键词：Fluorescence spectroscopy - Fluorescence - Probes - Molecules
- Photothermal Fe3O4 nanoparticles induced immunogenic ferroptosis for synergistic colorectal cancer therapy被引量：68收藏
- 作者：Li, Yue Chen, Jia Xia, Qi Shang, Jing He, Yujie Li, Zhi Chen, Yingying Gao, Feng Yu, Xi Yuan, Zeting Yin, Peihao
- 机构：Shanghai Univ Tradit Chinese Med;Shanghai Univ Tradit Chinese;Shanghai Univ Tradit Chinese Med;East China Univ Sci & Technol;Anhui Med Univ
- 来源：JOURNAL OF NANOBIOTECHNOLOGY 2024
- 关键词：Photothermal therapy Ferroptosis ICD Immunotherapy CRC
- An Oral H2S Responsive Cu5.4O Nanozyme Platform with Strong ROS/H2S Scavenging Capacity for the Treatment of Colitis被引量：66收藏
- 作者：Ma, Ying Tu, Yixing Chen, Yang Chen, Xinyi Pan, Xier Sun, Mingyue Fu, Xiuzhi Zou, Jiafeng Gao, Feng
- 机构： Shanghai Frontier Science Center of Optogenetic Techniques for Cell Metabolism; Department of Pharmacy; Shanghai Key Laboratory of Functional Materials Chemistry; Pharmaceutical Engineering and Process of Chemical Engineering Research Center
- 来源：ACS Applied Materials and Interfaces 2025
- 关键词：Scavenging
- Absorption Characteristics of Chitobiose and Chitopentaose in the Human Intestinal Cell Line Caco-2 and Everted Gut Sacs被引量：37收藏
- 作者：Chen, Ping Zhao, Mengyao Chen, Qiming Fang, Liqiang Gao, Feng Zhao, Liming
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;SCICBT
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2019
- 关键词：chitooligosaccharide everted gut sac model intestinal absorption Caco-2 cell model glucose transporter 2 (GLUT2)
- Spatiotemporally controllable diphtheria toxin expression using a light-switchable transgene system combining multifunctional nanoparticle delivery system for targeted melanoma therapy被引量：28收藏
- 作者：He, Muye Wang, Yan Chen, Xianjun Zhao, Yuzheng Lou, Kaiyan Wang, Yujie Huang, Lei Hou, Xinyu Xu, Jiajun Cai, Xiaoran Cheng, Yi Lan, Minbo Yang, Yi Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF CONTROLLED RELEASE 2020
- 关键词：Light-switchable gene expression Diphtheria toxin Melanoma Nanoparticle delivery system
- Antioxidant and immunomodulatory activities of Polysaccharides from Moxa (Artemisia argyi) Leaf被引量：25收藏
- 作者：Lan, Min-Bo Zhang, Yan-Hong Zheng, Ying Yuan, Hui-Hui Zhao, Hong-Li Gao, Feng
- 机构： Shanghai Key Laboratory of Functional Materials Chemistry; Key Laboratory for Ultrafine Materials of Ministry of Education; Department of Pharmaceutics
- 来源：Food Science and Biotechnology 2010
- 关键词：Glucose - T-cells - Cell proliferation - Antioxidants
- Biological Hyperthermia-Inducing Nanoparticles for Specific Remodeling of the Extracellular Matrix Microenvironment Enhance Pro-Apoptotic Therapy in Fibrosis被引量：24收藏
- 作者：Zhang, Jinru Ji, Keqin Ning, Yuanmeng Sun, Lingna Fan, Mingrui Shu, Chunjie Zhang, Ziqi Tu, Tianyu Cao, Jingyun Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS NANO 2023
- 关键词：fibrosis exosome and liposome hybrid nanoparticles hyperthermia 2 4-dinitrophenol remodelingof the extracellular matrix microenvironment
- Effects of Ganoderic acid Me on inhibiting multidrug resistance and inducing apoptosis in multidrug resistant colon cancer cells被引量：24收藏
- 作者：Jiang, Zijing Jin, Tiantian Gao, Feng Liu, Jianwen Zhong, Jianjiang Zhao, Heng
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;Shanghai Jiao Tong Univ;Shanghai Chest Hosp
- 来源：PROCESS BIOCHEMISTRY 2011
- 关键词：Ganoderic acid Me Multidrug resistance MDR1 MRPs Apoptosis
- Supramolecules-Guided Synthesis of Brightly Near-Infrared Au22 Nanoclusters with Aggregation-Induced Emission for Bioimaging被引量：20收藏
- 作者：Wei, Yifei Luan, Weiling Gao, Feng Hou, Xinyu
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：PARTICLE & PARTICLE SYSTEMS CHARACTERIZATION 2019
- 关键词：bioimaging growth process near-infrared rapid synthesis supramolecules-guided assembly
- Spatiotemporally controlled Pseudomonas exotoxin transgene system combined with multifunctional nanoparticles for breast cancer antimetastatic therapy被引量：16收藏
- 作者：Cheng, Yi Zou, Jiafeng He, Muye Hou, Xinyu Wang, Hongtao Xu, Jiajun Yuan, Zeting Lan, Minbo Yang, Yi Chen, Xianjun Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Sci
- 来源：JOURNAL OF CONTROLLED RELEASE 2024
- 关键词：Spatiotemporally controlled gene expression cancer -associated fibroblasts Multifunctional nanoparticles Pseudomonas exotoxin A Antimetastasis therapy Breast cancer
- Tofacitinib Citrate Coordination-Based Dual-Responsive/Scavenge Nanoplatform Toward Regulate Colonic Inflammatory Microenvironment for Relieving Colitis被引量：16收藏
- 作者：Zou, Jiafeng Jiang, Kun Chen, You Ma, Ying Xia, Chuanhe Ding, Wenxing Yao, Min Lin, Yiting Chen, Yanzuo Zhao, Yuzheng Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Med Sci;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ADVANCED HEALTHCARE MATERIALS 2024
- 关键词：colitis colonic inflammatory microenvironment coordination nanoplatform dual-responsive dual-scavenge tofacitinib citrate
- Incorporating zinc coordination driven nanozyme into chitosan and hyaluronic acid based nanoplatform for scavenging H2S/ROS in managing inflammatory bowel disease被引量：9收藏
- 作者：Zou, Jiafeng Ding, Wenxing Chen, You Pan, Xier Fu, Xiuzhi Zheng, Shulei Lin, Yiting Xia, Chuanhe Ma, Ying Zhang, Xiaochun Wu, Shuang Gao, Feng
- 机构：East China Univ Sci & Technol;Yangzhou Univ;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CARBOHYDRATE POLYMERS 2025
- 关键词：Nanozyme Reactive oxygen species Hydrogen sulfide Chitosan Hyaluronic acid Inflammatory bowel disease
- Sequential Rocket-Mode Bioactivating Ticagrelor Prodrug Nanoplatform Combining Light-Switchable Diphtherin Transgene System for Breast Cancer Metastasis Inhibition被引量：7收藏
- 作者：Zou, Jiafeng Sun, Rui He, Muye Chen, You Cheng, Yi Xia, Chuanhe Ma, Ying Zheng, Shulei Fu, Xiuzhi Yuan, Zeting Lan, Minbo Lou, Kaiyan Chen, Xianjun Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Univ Tradit Chinese Med;East China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2023
- 关键词：breast cancer metastasis LightOn system ticagrelor cell membrane fusionliposomes sequential bioactivatingprodrug
- Spatiotemporally controllable diphtherin transgene system and neoantigen immunotherapy被引量：7收藏
- 作者：He, Muye Sun, Yuji Cheng, Yi Wang, Jie Zhang, Miao Sun, Rui Hou, Xinyu Xu, Jiajun He, Hai Wang, Hongtao Yuan, Zeting Lan, Minbo Zhao, Yuzheng Yang, Yi Chen, Xianjun Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Shanghai Univ Tradit Chinese Med;East China Univ Sci & Technol;Chinese Acad Med Sci
- 来源：JOURNAL OF CONTROLLED RELEASE 2023
- 关键词：Light-switchable diphtherin gene expression Melanoma Immunotherapy Neoantigen Nanoparticle delivery system
- An anti-miR-301a and zinc coordination driven nanozyme loaded in nanoparticle for oral therapy of inflammatory bowel disease based on colitis microenvironment regulation被引量：6收藏
- 作者：Zou, Jiafeng Xia, Chuanhe Yao, Min Pan, Xier Zheng, Shulei Lin, Yiting Zhao, Xinlin Wang, Yanwen Chen, Yanzuo Lan, Minbo Wang, Junshan Gao, Feng
- 机构：East China Univ Sci & Technol;Tongji Univ;Bengbu First Peoples Hosp;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHEMICAL ENGINEERING JOURNAL 2025
- 关键词：Coordination driven nanozyme Anti-miR-301a Zinc Colitis microenvironment regulation Inflammatory bowel disease Oral nanoparticle
- Rapamycin and Hyperoside-Co-loaded Macrophage Delivery System Enhanced Pulmonary Fibrosis Therapy by Autophagy Upregulation and Epithelial-to-Mesenchymal Transition Inhibition被引量：4收藏
- 作者：Wang, Qi Ning, Yuanmeng Zhang, Jinru Du, Xu Xu, Zihan Hu, Yongcheng Gao, Feng Chen, Yanzuo
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2024
- 关键词：pulmonary fibrosis autophagy epithelial-to-mesenchymaltransition macrophage drug delivery system extracellulartraps
- Application of Mesoscale Simulation to Explore the pH Response of Eudragit S100 Used as the Novel Colon-Targeted Powder of Pulsatilla Saponin D被引量：3收藏
- 作者：Gong, Mingcheng Chen, Zhenhua Zhou, Liangliang Gao, Feng Cheng, Jianxin Zou, Wanqing
- 机构：Jiangxi Sci & Technol Normal Univ;East China Univ Sci & Technol
- 来源：JOURNAL OF NANOMATERIALS 2021
- 关键词：Controlled drug delivery - Micelles - Molecular dynamics - Particle dynamics - pH - Targeted drug delivery
- Oral cerium-based nanoplatform conjugated with gold to load anti-miR-301a for pH-transited multi-modal therapy of inflammatory bowel disease被引量：0收藏
- 作者：Zou, Jiafeng Ji, Qingdong Pan, Xier Lin, Yiting Zhao, Xinlin Chen, Xinyi Yang, Liping Lu, Jing Zheng, Shuhui Zhang, Zhuo Jiang, Kun Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHEMICAL ENGINEERING JOURNAL 2026
- 关键词：Oral nanoplatform Anti-miR-301a pH-transited multi-modal therapy Inflammatory bowel disease Cerium-based nanozyme Anti-fibrosis
- A ROS-ResponsiveDoxorubicin-Loaded Liposomal StrategyReduces Postablation Electrical Conduction Recovery in a CARTO-GuidedCanine Right Atrial Model被引量：0收藏
- 作者：Zhuge, Ying Yang, Liping Ge, Yulong Ji, Qingdong Lu, Jing Zheng, Shuhui Wang, Yiting Sun, Mingyue Zou, Jiafeng Wang, Fang Gao, Feng
- 机构：Shanghai Jiao Tong Univ;East China Univ Sci & Technol
- 来源：ACS APPLIED MATERIALS & INTERFACES 2026
- 关键词：radiofrequency catheter ablation ROS-responsive liposome apoptosis induction canine models CARTO system
- HyperDC: A Non-UniformHypergraph Framework for Dual-and Higher-Order Drug Combination Recommendation Across Diverse ComplexDiseases被引量：0收藏
- 作者：Yu, Hongbo Chen, Xinyi Song, Wenxiang Xiong, Le Li, Xinmin Wang, Ze Pan, Fei Li, Weihua Liu, Guixia Gao, Feng Tang, Yun
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF CHEMICAL INFORMATION AND MODELING 2026
- 关键词：Diagnosis - Disease control - Diseases - Drug discovery - Screening
- Chemotaxis-guided nanoplatform for non-alcoholic steatohepatitis therapy via macrophage reprogramming, hepatoprotection and gut microbiome modulation被引量：0收藏
- 作者：Pan, Xier Chen, Xinyi Ma, Ying Zou, Jiafeng Lin, Yiting Zhao, Xinlin Wang, Yanwen Tang, Yun Gao, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOMATERIALS 2026
- 关键词：M2 macrophage-derived membrane Nanoplatform Obeticholic acid Non-alcoholic steatohepatitis Macrophage reprogramming Gut microbiome modulation
