成果/Result
- A cytosensor based on NiO nanoparticle-enhanced surface plasmon resonance for detection of the breast cancer cell line MCF-7被引量：43收藏
- 作者：Jia, Shengsong Li, Pengfei Koh, Kwangnak Chen, Hongxia
- 机构：Shanghai Univ;E China Univ Sci & Technol;Pusan Natl Univ
- 来源：MICROCHIMICA ACTA 2016
- 关键词：Aptamer His tag MUC-1 Diagnosis Tumor marker Islet beta cells Biosensor
- Improved breast cancer cell-specific intracellular drug delivery and therapeutic efficacy by coupling decoration with cell penetrating peptide and SP90 peptide被引量：15收藏
- 作者：Fan, Li-Qiang Du, Guo-Xiu Li, Peng-Fei Li, Ming-Wei Sun, Yao Zhao, Li-Ming
- 机构：East China Univ Sci & Technol
- 来源：BIOMEDICINE & PHARMACOTHERAPY 2016
- 关键词：Cell-penetrating peptide Homing peptide Targeted drug delivery Breast cancer therapy VPR
- Enhanced anti-tumor activity of trichosanthin after combination with a human-derived cell-penetrating peptide, and a possible mechanism of activity被引量：13收藏
- 作者：Lu, Ye-Zhou Li, Peng Fei Li, Yan-Zhong Luo, Fan Guo, Chao Lin, Bin Cao, Xue-Wei Zhao, Jian Wang, Fu-Jun
- 机构：East China Univ Sci & Technol;Shanghai Univ Tradit Chinese Med;Zhejiang Reachall Pharmaceut Co Ltd
- 来源：FITOTERAPIA 2016
- 关键词：Trichosanthin Cell-penetrating peptide Tumor therapy Apoptosis
- Enhancing tumor-specific intracellular delivering efficiency of cell-penetrating peptide by fusion with a peptide targeting to EGFR被引量：13收藏
- 作者：Long The Nguyen Yang, Xu-Zhong Du, Xuan Wang, Jia-Wei Zhang, Rui Zhao, Jian Wang, Fu-Jun Dong, Yang Li, Peng-Fei
- 机构：E China Univ Sci & Technol;Zhejiang Reachall Pharmaceut Co Ltd;Shanghai Univ Tradit Chinese Med
- 来源：AMINO ACIDS 2015
- 关键词：Cell-penetrating peptide Tumor-homing peptide Targeted drug delivery Growth factor
- Alter codon bias of the P. pastoris genome to overcome a bottleneck in codon optimization strategy development and improve protein expression被引量：11收藏
- 作者：Zhang, Siyu Lin, Ru Cui, Luyao Jiang, Tianyi Shi, Jiacheng Li, Pengfei Zhou, Mian
- 机构：East China Univ Sci & Technol;China Innovat Ctr Roche
- 来源：MICROBIOLOGICAL RESEARCH 2024
- 关键词：Codon optimization Pichia pastoris Protein expression Chassis cells
- The discovery of new scaffold of plant activators: From salicylic acid to benzotriazole被引量：10收藏
- 作者：Chang, Kang Chen, Jian-Qin Shi, Yan-Xia Sun, Mei-Jian Li, Peng-Fei Zhao, Zhen-Jiang Zhu, Wei-Ping Li, Hong-Lin Xu, Yu-Fang Li, Bao-Ju Qian, Xu-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Agr Sci
- 来源：CHINESE CHEMICAL LETTERS 2017
- 关键词：Plant activator Systemic acquired resistance Salicylic acid Benzotriazole Virtual screening
- Cell-Free Biosensing Genetic Circuit Coupled with Ribozyme Cleavage Reaction for Rapid and Sensitive Detection of Small Molecules被引量：9收藏
- 作者：Li, Wenxing Xu, Yiming Zhang, Yue Li, Pengfei Zhu, Xiaoli Feng, Chang
- 机构：Shanghai Univ;Tongji Univ;East China Univ Sci & Technol;Shanghai Univ
- 来源：ACS SYNTHETIC BIOLOGY 2023
- 关键词：genetic circuit in vitro transcription ribozyme IPTG inhibitory drugs screening 3D-printedsensor array
- Novel Fluorescence Arginine Analogue as a Sensor for Direct Identification and Imaging of Nitric Oxide Synthase-like Enzymes in Plants被引量：5收藏
- 作者：Chang, Kang Guo, Tongtong Li, Pengfei Liu, Yin Xu, Yufang Fang, Yuda Qian, Xuhong
- 机构：East China Univ Sci & Technol;Chinese Acad Sci
- 来源：SCIENTIFIC REPORTS 2016
- Practices and exploration on competition of molecular biological detection technology among students in food quality and safety major被引量：4收藏
- 作者：Chang, Yaning Peng, Yuke Li, Pengfei Zhuang, Yingping
- 机构：East China Univ Sci & Technol
- 来源：BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION 2017
- 关键词：Molecular biological detection undergraduate education pork and beef identification food safety laboratory exercises
- Effectively enhancing cytotoxic and apoptotic effects of alpha-momorcharin by integrating a heparin-binding peptide被引量：4收藏
- 作者：Tan, Meng-Jie Cao, Xue-Wei Li, Peng-Fei Zhai, Yi-Zhou Zhou, Yu Liu, Ye-Jun Zhao, Jian Wang, Fu-Jun
- 机构：East China Univ Sci & Technol;Zhejiang Reachall Pharmaceut Co Ltd;Shanghai Univ Chinese Tradit Med
- 来源：BIOTECHNOLOGY AND APPLIED BIOCHEMISTRY 2017
- 关键词：antitumor activity apoptosis cell-penetrating peptides heparin-binding peptide alpha-MMC-HBP
- Platycodin D reduces PD-L1 levels by inhibiting LXR-β activity and combines with nintedanib to enhance the tumor-killing effect of T cells被引量：2收藏
- 作者：Lei, Jin Cao, Xue-Wei Li, Peng-Fei Zhao, Jian Wang, Fu-Jun
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Zhejiang Fonow Med Co Ltd;Shanghai Univ Tradit Chinese Med
- 来源：FEBS LETTERS 2024
- 关键词：cancer therapy cholesterol immunotherapy MHC PD-L1 platycodin D
- Real-Time Quantitative PCR Analysis of the Expression Pattern of the Hypoglycemic Polypeptide-P Gene in Momordica charantia被引量：1收藏
- 作者：Wang, Yi-Shuai Zeng, Xiang-Qing Yang, Xu-Zhong Liu, Wei Li, Peng-Fei Wang, Fu-Jun Zhao, Jian
- 机构：East China Univ Sci & Technol;Shanghai Univ Tradit Chinese Med;Zhejiang Reachall Pharmaceut Co Ltd
- 来源：GENES 2019
- 关键词：Momordica charantia hypoglycemic polypeptide-P qPCR Western blotting expression pattern
- Bridging the biochemistry lecture and laboratory courses: Construction and application of the "Innovative Experimental Design" module被引量：1收藏
- 作者：Li, Pengfei Zhang, Boya He, Shuaifei Lu, Yuqing Jiang, Wenli Zhong, Qingsong Quan, Shu Wu, Haizhen Zhou, Mian
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOCHEMISTRY AND MOLECULAR BIOLOGY EDUCATION 2024
- 关键词：biochemistry course development laboratory course microbial fuel cells
- Inception-level signal amplification: Cascaded DNAzyme-Cas9 nickase achieves sub-nanomolar kanamycin tracking被引量：0收藏
- 作者：Xu, Wen Cheng, Yutian Sun, Kexin Wu, Yue Xu, Yiming Ye, Jiang Li, Pengfei Wu, Haizhen
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ANALYTICA CHIMICA ACTA 2026
- 关键词：Kanamycin Aptamer DNAzyme Cas9 nickase
- Machine learning-optimized long single-stranded DNA synthesis technology empowers high-precision diagnostic-therapeutic integration in living cells被引量：0收藏
- 作者：Zhang, Yue Xu, Yiming Ding, Zhihua Cheng, Yutian Gao, Yu Ye, Jiang Zhang, Huizhan Li, Pengfei Wu, Haizhen
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：NUCLEIC ACIDS RESEARCH 2026
- A novel CRISPR-Cas9 nickase-mediated rolling circle amplification (CRIRCA) technique for gene identification and quantitative analysis of extrachromosomal DNA被引量：0收藏
- 作者：Song, Yuchen Guan, Chaoyang Zhang, Yue Xu, Yiming Li, Pengfei Luo, Liqiang Feng, Chang Chen, Guifang
- 机构：Shanghai Univ;Shanghai Univ;East China Univ Sci & Technol;Shanghai Univ
- 来源：JOURNAL OF ADVANCED RESEARCH 2026
- 关键词：ecDNA detection CRIRCA CRISPR-Cas9 Tumor markers Breast cancer
- Metabolic engineering of Bacillus subtilis for high-yield surfactin production被引量：0收藏
- 作者：Wang, Yong Li, Hanqing Mao, Yue Li, Pengfei Wu, Haizhen Ye, Jiang Zhang, Huizhan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS 2026
- 关键词：Surfactin Bacillus subtilis Metabolic engineering P43 promoter Tolerance engineering
