成果/Result
- SoNar, a Highly Responsive NAD+/NADH Sensor, Allows High-Throughput Metabolic Screening of Anti-tumor Agents被引量：321收藏
- 作者：Zhao, Yuzheng Hu, Qingxun Cheng, Feixiong Su, Ni Wang, Aoxue Zou, Yejun Hu, Hanyang Chen, Xianjun Zhou, Hai-Meng Huang, Xinzhi Yang, Kai Zhu, Qian Wang, Xue Yi, Jing Zhu, Linyong Qian, Xuhong Chen, Lixin Tang, Yun Loscalzo, Joseph Yang, Yi
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol;Tsinghua Univ
- 来源：CELL METABOLISM 2015
- In vivo monitoring of cellular energy metabolism using SoNar, a highly responsive sensor for NAD+/NADH redox state被引量：136收藏
- 作者：Zhao, Yuzheng Wang, Aoxue Zou, Yejun Su, Ni Loscalzo, Joseph Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Harvard Med Sch
- 来源：NATURE PROTOCOLS 2016
- Ultrasensitive sensors reveal the spatiotemporal landscape of lactate metabolism in physiology and disease被引量：106收藏
- 作者：Li, Xi Zhang, Yinan Xu, Lingya Wang, Aoxue Zou, Yejun Li, Ting Huang, Li Chen, Weicai Liu, Shuning Jiang, Kun Zhang, Xiuze Wang, Dongmei Zhang, Lijuan Zhang, Zhuo Zhang, Zeyi Chen, Xianjun Jia, Wei Zhao, Aihua Yan, Xinfeng Zhou, Haimeng Zhu, Linyong Ma, Xinran Ju, Zhenyu Jia, Weiping Wang, Congrong Loscalzo, Joseph Yang, Yi Zhao, Yuzheng
- 机构：East China Univ Sci & Technol;Chinese Acad Med Sci;Chinese Acad Sci;Shanghai Jiao Tong Univ Affiliated Peoples Hosp 6;East China Normal Univ
- 来源：CELL METABOLISM 2023
- Illuminating NAD+ Metabolism in Live Cells and In Vivo Using a Genetically Encoded Fluorescent Sensor被引量：95收藏
- 作者：Zou, Yejun Wang, Aoxue Huang, Li Zhu, Xudong Hu, Qingxun Zhang, Yinan Chen, Xianjun Li, Fengwen Wang, Qiaohui Wang, Hu Liu, Renmei Zuo, Fangting Li, Ting Yao, Jing Qian, Yajin Shi, Mei Yue, Xiao Chen, Weicai Zhang, Zhuo Wang, Congrong Zhou, Yong Zhu, Linyong Ju, Zhenyu Loscalzo, Joseph Yang, Yi Zhao, Yuzheng
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol;Hangzhou Normal Univ;Shanghai Jiao Tong Univ
- 来源：DEVELOPMENTAL CELL 2020
- Analysis of redox landscapes and dynamics in living cells and in vivo using genetically encoded fluorescent sensors被引量：83收藏
- 作者：Zou, Yejun Wang, Aoxue Shi, Mei Chen, Xianjun Liu, Renmei Li, Ting Zhang, Chenxia Zhang, Zhuo Zhu, Linyong Ju, Zhenyu Loscalzo, Joseph Yang, Yi Zhao, Yuzheng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Jinan Univ;Harvard Med Sch
- 来源：NATURE PROTOCOLS 2018
- A genetically encoded toolkit for tracking live-cell histidine dynamics in space and time被引量：32收藏
- 作者：Hu, Hanyang Gu, Yanfang Xu, Lei Zou, Yejun Wang, Aoxue Tao, Rongkun Chen, Xianjun Zhao, Yuzheng Yang, Yi
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：SCIENTIFIC REPORTS 2017
- Comprehensive multiscale analysis of lactate metabolic dynamics in vitro and in vivo using highly responsive biosensors被引量：27收藏
- 作者：Wang, Aoxue Zou, Yejun Liu, Shuning Zhang, Xiuze Li, Ting Zhang, Lijuan Wang, Ruwen Xia, Yale Li, Xie Zhang, Zhuo Liu, Tiemin Ju, Zhenyu Wang, Ru Loscalzo, Joseph Yang, Yi Zhao, Yuzheng
- 机构：East China Univ Sci & Technol;Chinese Acad Med Sci;Shanghai Univ Sport;Fudan Univ;Jinan Univ
- 来源：NATURE PROTOCOLS 2024
- Monitoring cellular redox state under hypoxia using a fluorescent sensor based on eel fluorescent protein被引量：22收藏
- 作者：Hu, Hanyang Wang, Aoxue Huang, Li Zou, Yejun Gu, Yanfang Chen, Xianjun Zhao, Yuzheng Yang, Yi
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol
- 来源：FREE RADICAL BIOLOGY AND MEDICINE 2018
- 关键词：Eel fluorescent protein UnaG Redox state Real-time monitoring RoUnaG Oxygen-independent Hypoxia
- Lighting up arginine metabolism reveals itsfunctional diversity in physiology and pathology被引量：21收藏
- 作者：Li, Rui Li, Yan Jiang, Kun Zhang, Lijuan Li, Ting Zhao, Aihua Zhang, Zhuo Xia, Yale Ge, Kun Chen, Yaqiong Wang, Chengnuo Tang, Weitao Liu, Shuning Lin, Xiaoxi Song, Yuqin Mei, Jie Xiao, Chun Wang, Aoxue Zou, Yejun Li, Xie Chen, Xianjun Ju, Zhenyu Jia, Wei Loscalzo, Joseph Sun, Yu Fang, Wei Yang, Yi Zhao, Yuzheng
- 机构：East China Univ Sci & Technol;Chinese Acad Med Sci;Univ Chinese Acad Sci;Shanghai Jiao Tong Univ;Shanghai Jiao Tong Univ
- 来源：CELL METABOLISM 2025
- Using Fractional Intensities of Time-resolved Fluorescence to Sensitively Quantify NADH/NAD+ with Genetically Encoded Fluorescent Biosensors被引量：20收藏
- 作者：Chang, Mengfang Li, Lei Hu, Hanyang Hu, Qingxun Wang, Aoxue Cao, Xiaodan Yu, Xiantong Zhang, Sanjun Zhao, Yuzheng Chen, Jinquan Yang, Yi Xu, Jianhua
- 机构：East China Normal Univ;Shanghai Collaborat Innovat Ctr Biomfg Technol;CAS Ctr Excellence Brain Sci;East China Univ Sci & Technol
- 来源：SCIENTIFIC REPORTS 2017
- RNAi screens identify HES4 as a regulator of redox balance supporting pyrimidine synthesis and tumor growth被引量：12收藏
- 作者：He, Jing Wang, Aoxue Zhao, Qin Zou, Yejun Zhang, Zhuo Sha, Nannan Hou, Guofang Zhou, Bei Yang, Yi Chen, Tao Zhao, Yuzheng Jiang, Yuhui
- 机构：Shanghai Jiao Tong Univ;East China Univ Sci & Technol;Chinese Acad Med Sci;Tongji Univ;Tongji Univ
- 来源：NATURE STRUCTURAL & MOLECULAR BIOLOGY 2024
- Imaging the Redox States of Live Cells with the Time-Resolved Fluorescence of Genetically Encoded Biosensors被引量：12收藏
- 作者：Li, Lei Zhang, Changcheng Wang, Peng Wang, Aoxue Zhou, Jiasheng Chen, Guoqing Xu, Jianhua Yang, Yi Zhao, Yuzheng Zhang, Sanjun Tian, Yang
- 机构：East China Normal Univ;East China Univ Sci & Technol;East China Univ Sci & Technol;Jiangnan Univ;Chinese Acad Sci
- 来源：ANALYTICAL CHEMISTRY 2019
- 关键词：Cells - Fluorescence - Cytology - Bioimaging
- Sensitive detection via the time-resolved fluorescence of circularly permuted yellow fluorescent protein biosensors被引量：8收藏
- 作者：Li, Lei Cheng, Yuchi Shen, Shiyu Zhou, Jiasheng Wang, Aoxue Chen, Guoqing Xu, Jianhua Yang, Yi Zhao, Yuzheng Zhang, Sanjun Tian, Yang
- 机构：East China Normal Univ;East China Univ Sci & Technol;Jiangnan Univ;Chinese Acad Sci;East China Univ Sci & Technol
- 来源：SENSORS AND ACTUATORS B-CHEMICAL 2020
- 关键词：Circularly permuted fluorescent proteins Time-resolved fluorescence Biosensor Fluorescent lifetime imaging
- Multicoloured fluorescent indicators for live-cell and in vivo imaging of inorganic mercury dynamics被引量：6收藏
- 作者：Tao, Rongkun Shi, Mei Zou, Yejun Cheng, Di Wang, Qiaohui Liu, Renmei Wang, Aoxue Zhu, Jiahuan Deng, Lei Hu, Hanyang Chen, Xianjun Du, Jiulin Zhu, Weiping Zhao, Yuzheng Yang, Yi
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：FREE RADICAL BIOLOGY AND MEDICINE 2018
- 关键词：Inorganic mercury Multicoloured fluorescent indicators Live-cell imaging In vivo imaging Oxidative damage
- Nitrogen-Boosted H2O2 Production of Arginine-Polyphenol Nanozyme Drives Oxidative Eustress for Hair Regeneration被引量：1收藏
- 作者：Wang, Yifei Yang, Yaojia Wang, Aoxue Shen, Chen Tan, Shenliang Liu, Changsheng Zhao, Yuzheng Qu, Xue
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;Chinese Acad Med Sci
- 来源：ADVANCED SCIENCE 2026
- 关键词：hair regeneration hydrogen peroxide nanoenzymes oxidative eustress polyphenol
