- Total Synthesis and Stereochemical Assignment of Delavatine A: Rh-Catalyzed Asymmetric Hydrogenation of Indene-Type Tetrasubstituted Olefins and Kinetic Resolution through Pd Catalyzed Triflamide-Directed C-H Olefination被引量：77收藏
- 作者：Zhang, Zhongyin Wang, Jinxin Li, Jian Yang, Fan Liu, Guodu Tang, Wenjun He, Weiwei Fu, Jian-Jun Shen, Yun-Heng Li, Ang Zhang, Wei-Dong
- 机构：East China Univ Sci & Technol;Second Mil Med Univ;Chinese Acad Sci
- 来源：JOURNAL OF THE AMERICAN CHEMICAL SOCIETY 2017
- 关键词：Synthesis (chemical) - Cell culture - Kinetics - Olefins - Reaction intermediates - Stereochemistry - Palladium compounds - Polycyclic aromatic hydrocarbons - Catalysis - Hydrogenation - Sulfur compounds
- 质疑
- AMD3100 inhibits brain-specific metastasis in lung cancer via suppressing the SDF-1/CXCR4 axis and protecting blood-brain barrier被引量：24收藏
- 作者：Li, Hongru Chen, Yusheng Xu, Nengluan Yu, Meie Tu, Xunwei Chen, Zhengwei Lin, Ming Xie, Baosong Fu, Jianjun Han, Lili
- 机构：Fujian Med Univ;Fujian Inst Four Resp Dis;East China Univ Sci & Technol;Fujian Key Lab Cardiovasc Dis
- 来源：AMERICAN JOURNAL OF TRANSLATIONAL RESEARCH 2017
- 关键词：Brain metastasis SDF-1 CXCR4 AMD3100 lung cancer
- 质疑
- Systematic Analysis of the Multiple Bioactivities of Green Tea through a Network Pharmacology Approach被引量：20收藏
- 作者：Zhang, Shoude Shan, Lei Li, Qiao Wang, Xia Li, Shiliang Zhang, Yuan Fu, Jianjun Liu, Xiaofeng Li, Honglin Zhang, Weidong
- 机构：E China Univ Sci & Technol;Second Mil Med Univ
- 来源：EVIDENCE-BASED COMPLEMENTARY AND ALTERNATIVE MEDICINE 2014
- 质疑
- Chemical Constituents of Plants from the Genus Buxus被引量：16收藏
- 作者：Zhang, Jie Qin, Xiang-Yang Zhang, Shou-De Xu, Xu-Sheng Pei, Jin-Peng Fu, Jian-Jun
- 机构：E China Univ Sci & Technol;Fourth Mil Med Univ
- 来源：CHEMISTRY & BIODIVERSITY 2015
- 质疑
- Delavatine A, a structurally unusual cyclopenta[de]isoquinoline alkaloid from Incarvillea delavayi被引量：13收藏
- 作者：Zhang, Zhongyin Yang, Fan Fu, Jian-Jun Shen, Yun-Heng He, Weiwei Zhang, Wei-Dong
- 机构：Second Mil Med Univ;East China Univ Sci & Technol
- 来源：RSC ADVANCES 2016
- 关键词：Bioactivity - Drug products - Metabolites - Cell culture - Spectroscopic analysis
- 质疑
- Synthesis, cytotoxicity and inhibition of NO production of ivangustin enantiomer analogues被引量：12收藏
- 作者：Qin, Xiang-Yang Chen, Bing-Yang Fu, Jian-Jun Shan, Lei Lei, Xiao-Guang Zhang, Wei-Dong
- 机构：Second Mil Med Univ;E China Univ Sci & Technol;Being NIBS;Fourth Mil Med Univ
- 来源：EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY 2015
- 关键词：Ivangustin Natural product analogues Sesquiterpene lactone Inhibition of NO production Cytotoxicity
- 质疑
- Proteomic analysis of the effect of diclazuril on second-generation merozoites of Eimeria tenella被引量：10收藏
- 作者：Shen, Xiao-jiong Li, Tao Fu, Jian-jun Zhang, Ke-yu Wang, Xiao-yang Liu, Yin-chun Zhang, Hua-jing Fan, Chao Fei, Cheng-zhong Xue, Fei-qun
- 机构：Chinese Acad Agr Sci;E China Univ Sci & Technol
- 来源：PARASITOLOGY RESEARCH 2014
- 质疑
- Synthesis and effects of new caffeic acid derivatives on nitric oxide production in lipopolysaccharide- induced RAW 264.7 macrophages被引量：10收藏
- 作者：Zhang, Jie Xu, Liu-Xin Xu, Xu-Sheng Li, Bo-Wei Wang, Rui Fu, Jian-Jun
- 机构：E China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL MEDICINE 2014
- 关键词：Caffeic acid structure modification condensation nitric oxide anti-inflammatory
- 质疑
- 浅谈化学对医学发展的贡献被引量：8收藏
- 作者：秦向阳 刘建强 李明华 兰婷 付建军 何炜 辛春艳
- 机构：第四军医大学药学院化学教研室;广东医学院药学院;华东理工大学药学院;第四军医大学药学院教学办
- 来源：《医学争鸣》 2014
- 关键词：化学 医学 医药学
- 摘要：化学是一门满足社会需要的核心学科。随着化学学科的不断发展,化学与其他学科的互相影响、互相渗透、互相综合越来越密切;尤其化学与医学之间的关系极其密切。在未来的生命科学中,化学必将为我们揭开生命的奥秘,为研制治疗绝症的灵丹妙...
- 下载全文在线阅读质疑
- Synthesis, Preliminary Bioevaluation and Computational Analysis of Caffeic Acid Analogues被引量：7收藏
- 作者：Liu, Zhiqian Fu, Jianjun Shan, Lei Sun, Qingyan Zhang, Weidong
- 机构：Second Mil Med Univ;E China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES 2014
- 关键词：anti-inflammatory caffeic acid amides synthesis pharmacophore target predication
- 质疑
- Inactivation of RhoA for Hypertension Treatment Through the TRPV4-RhoA-RhoGDI1 Axis被引量：4收藏
- 作者：Wang, Jiawen Yuan, Zhen Yu, Na Jiao, Qian Zhou, Honglei Liao, Wenjie Shan, Jiwei Ruan, Shanshan Zhao, Yi Mo, Ya Qi, Luyao Li, Tiejun Fu, Jianjun Ke, Bowen Xu, Yufang Qian, Xuhong Zhang, Jian Zhao, Zhenjiang Li, Shiliang Wang, Rui Li, Honglin
- 机构：East China Univ Sci & Technol;East China Normal Univ;Sichuan Univ
- 来源：CIRCULATION 2025
- 关键词：AH001 cryoelectron microscopy hypertension muscle, smooth, vascular rhoA GTP-binding proteins TRPV cation channels
- 质疑
- Argutalactone, an unprecedented sesquiterpenoid lactone with a 6/5/7 tricyclic system from Incarvillea arguta被引量：3收藏
- 作者：Fu, Jian-Jun Wang, Li-Yan Li, Hong-Lin Qin, Jiang-Jiang Shen, Yun-Heng Cheng, Jia-Gao Jin, Hui-Zi Zhang, Wei-Dong
- 机构：Shanghai Jiao Tong Univ;E China Univ Sci & Technol;Second Mil Med Univ
- 来源：JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH 2012
- 关键词：Incarvillea arguta argutalactone sesquiterpenoid lactone density functional calculations
- 质疑
- A concise asymmetric total synthesis for structure elucidation of 5,6-secoiridoid from Incarvillea argute被引量：1收藏
- 作者：Fu, Jian-Jun Liu, Zhi-Qian Jin, Hui-Zi Zhang, Shou-De Sun, Qing-Yan Zhang, Wei-Dong
- 机构：East China Univ Sci & Technol;Second Mil Med Univ;Shanghai Jiao Tong Univ;Shanghai Inst Pharmaceut Ind
- 来源：RSC ADVANCES 2016
- 关键词：Synthesis (chemical) - Cancer cells
- 质疑
- CHEMICAL CONSTITUENTS OF THE AERIAL PARTS OF Aconitum kongboense被引量：1收藏
- 作者：Fu, Jian-Jun Qin, Jiang-Jiang Zeng, Qi Jin, Hui-Zi Zhang, Wei-Dong
- 机构：Shanghai Jiao Tong Univ;E China Univ Sci & Technol;Second Mil Med Univ
- 来源：CHEMISTRY OF NATURAL COMPOUNDS 2011
- 质疑
- MiR-9 Promotes Apoptosis Suppressing SMC1A Expression in GBM Cell Lines.被引量：0收藏
- 作者：Zu, Yong Zhu, Zhichuan Lin, Min Xu, Dafeng Liang, Yongjun Wang, Yueqian Qiao, Zhengdong Cao, Ting Yang, Dan Gao, Lili Jin, Pengpeng Zhang, Peng Fu, Jianjun Zheng, Jing
- 机构：Shanghai Key Laboratory of New Drug Design;Center for Medical Research and Innovation
- 来源：Current chemical genomics and translational medicine 2017
- 关键词：GBM SMC1A U251 U87 apoptosis miR-9
- 质疑
