成果/Result
- Improved transdermal permeability of ibuprofen by ionic liquid technology: Correlation between counterion structure and the physicochemical and biological properties被引量：62收藏
- 作者：Wu, Hao Deng, Zhaizhu Zhou, Bijian Qi, Minghui Hong, Minghuang Ren, Guobin
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF MOLECULAR LIQUIDS 2019
- 关键词：Ibuprofen Ionic liquids Molecular interaction Skin permeability Cytotoxicity
- Development of a gliclazide ionic liquid and its mesoporous silica particles: An effective formulation strategy to improve oral absorption properties被引量：58收藏
- 作者：Zhou, Bijian Teng, Dan Li, Jinghui Zhang, Yanhong Qi, Minghui Hong, Minghuang Ren, Guo-Bin
- 机构： Engineering Research Centre of Pharmaceutical Process Chemistry; Shanghai Key Laboratory of New Drug Design; State Key Laboratory of Bioreactor Engineering
- 来源：RSC Advances 2022
- 关键词：Silica - Targeted drug delivery - Molecules - Controlled drug delivery - Encapsulation - Solubility - Positive ions - Mesoporous materials - Physicochemical properties - Supersaturation
- Insight into the effect of cocrystal polymorphism / stoichiomorphism on thermodynamic and photoluminescence properties: a case study被引量：45收藏
- 作者：Han, Xianyang Yin, Yu Zhu, Fan Yao, Yichen Hong, Minghuang Qi, Minghui Zhu, Bin Ren, Guobin
- 机构： Laboratory of Pharmaceutical Crystal Engineering & Technology; State Key Laboratory of Bioreactor Engineering
- 来源：SSRN 2025
- 关键词：Crystal structure - Fluorescence - Fluorescence spectroscopy - Optical properties - Phase transitions - Photoluminescence - Polymorphism - Single crystals - Thermoanalysis - X ray diffraction
- Isostructural Levamisole Hydrochloride Ionic Cocrystal Solvates: High Z″ with a Low Melting Point被引量：40收藏
- 作者：Yao, Yi-Chen Jin, Zhe Hong, Minghuang Zhu, Bin Ren, Guo-Bin Qi, Ming-Hui
- 机构： Laboratory of Pharmaceutical Crystal Engineering & Technology
- 来源：Crystal Growth and Design 2024
- 关键词：Melting point - Single crystals - Surface analysis - Thermoanalysis
- Slow-Release Drug-Drug Cocrystals of Oxaliplatin with Flavonoids: Delaying Hydrolysis and Reducing Toxicity被引量：31收藏
- 作者：Yin, He-Mei Wu, Nan Zhou, Bi-Jian Hong, Ming-Huang Zhu, Bin Qi, Ming-Hui Ren, Guo-Bin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2021
- 关键词：Single crystals - Cancer cells - Controlled drug delivery - Fourier transform infrared spectroscopy - Dissolution - Targeted drug delivery - Cells - Flavonoids - X ray diffraction - Hydrogen bonds - Thermoanalysis - Toxicity - Cytology
- Ionic liquid form of donepezil: Preparation, characterization and formulation development被引量：31收藏
- 作者：Wu, Hao Fang, Fang Zheng, Lulu Ji, Weijie Qi, Minghui Hong, Minghuang Ren, Guobin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF MOLECULAR LIQUIDS 2020
- 关键词：Ionic liquids AlzhEImer's disease Donepezil Drug-in-adhesive patch Skin permeability
- Toward Understanding the Effect of Solvent Evaporation on the Morphology of PLGA Microspheres by Double Emulsion Method被引量：29收藏
- 作者：Si, Wei Yang, Qingqing Zong, Yuan Ren, Guobin Zhao, Ling Hong, Minghuang Xin, Zhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：INDUSTRIAL & ENGINEERING CHEMISTRY RESEARCH 2021
- 关键词：Emulsification - Evaporation - Morphology - Microspheres - Diffusion
- Cocrystals of Oxymatrine: Reducing Hygroscopicity and Affecting the Dissolution Rate被引量：25收藏
- 作者：Qi, Ming-Hui Li, Heng Zhu, Bin Hong, Minghuang Ren, Guo-Bin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2021
- 关键词：Dissolution - Hydrogen bonds - Metabolism
- Strategy for Efficient Discovery of Cocrystals via a Network-Based Recommendation Model被引量：22收藏
- 作者：Zheng, Lulu Zhu, Bin Wu, Zengrui Fang, Xiaoxue Hong, Minghuang Liu, Guixia Li, Weihua Ren, Guobin Tang, Yun
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2020
- Estimating Thermodynamic Stability Relationship of Polymorphs of Sofosbuvir被引量：22收藏
- 作者：Qi, Ming-Hui Hong, Ming-Huang Liu, Yan Wang, En-Fu Ren, Fu-Zheng Ren, Guo-Bin
- 机构：E China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2015
- 关键词：Solubility - Thermoanalysis - X ray powder diffraction - Free energy - Melting
- Cocrystals of Lenvatinib with Sulfamerazine and Salicylic Acid: Crystal Structure, Equilibrium Solubility, Stability Study, and Anti-Hepatoma Activity被引量：20收藏
- 作者：Hong, Minghuang Li, Shijia Ji, Weijie Qi, Ming-Hui Ren, Guo-bin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2021
- 关键词：Single crystals - Surface analysis - Crystal structure - Nuclear magnetic resonance spectroscopy - Salicylic acid - Differential scanning calorimetry - Amino acids - Fourier transform infrared spectroscopy - Thermogravimetric analysis - Hydrogen bonds - Drug delivery - Spectrometers - X ray diffraction
- Insight into the Formation of Cocrystals of Flavonoids and 4,4′-Vinylenedipyridine: Heteromolecular Hydrogen Bonds, Molar Ratio, and Structural Analysis被引量：19收藏
- 作者：Zhang, Yanhong Zhu, Bin Ji, Wei-Jie Guo, Chun-Yang Hong, Minghuang Qi, Ming-Hui Ren, Guo-Bin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2021
- 关键词：Hydrogen bonds - Single crystals - Molar ratio
- Cocrystals of flavonoids with 4,4′-ethylenebispyridine: Crystal structures analysis, dissolution behavior, and anti-tumor activity被引量：16收藏
- 作者：Zhang, Yanhong Yang, Rui Yin, He-Mei Zhou, Bijian Hong, Minghuang Zhu, Bin Qi, Ming-Hui Ren, Guo-Bin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF MOLECULAR STRUCTURE 2022
- 关键词：Tumors - Cancer cells - Single crystals - Dissolution
- Solubility correlation and thermodynamic analysis of two forms of Metaxalone in different pure solvents被引量：14收藏
- 作者：Hong, Minghuang Wu, Shiwang Qi, Minghui Ren, Guobin
- 机构：E China Univ Sci & Technol
- 来源：FLUID PHASE EQUILIBRIA 2016
- 关键词：Solubility Thermodynamic models Endothermic Entropy driven Nonspontaneous
- Study of Cycloxaprid Co-crystals: Characterization, Theory Calculation, Solubility, and Stability被引量：12收藏
- 作者：Li, Mengnan Wang, Jinling Xu, Xiaoyong Ren, Guobin Zhu, Bin Hong, Minghuang Li, Zhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2022
- 关键词：Chemical stability - Differential scanning calorimetry - Fourier transform infrared spectroscopy - Molecular orbitals - Nuclear magnetic resonance spectroscopy - Single crystals - Thermogravimetric analysis - X ray diffraction
- SMINBR: An Integrated Network and Chemoinformatics Tool Specialized for Prediction of Two-Component Crystal Formation被引量：11收藏
- 作者：Zheng, Lulu Zhu, Bin Wu, Zengrui Liang, Fang Hong, Minghuang Liu, Guixia Li, Weihua Ren, Guobin Tang, Yun
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF CHEMICAL INFORMATION AND MODELING 2021
- 关键词：Molecular interactions - Molecular structure - Crystals - Physicochemical properties
- Structure properties of scoparone: Polymorphs and cocrystals被引量：10收藏
- 作者：Chen, Jin-yao Wang, Xiao-yu Hong, Ming-huang Yi, Dong-xu Qi, Ming-hui Ren, Guo-bin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF MOLECULAR STRUCTURE 2019
- 关键词：Scoparone Polymorphs Cocrystals Crystal structure Powder dissolution study
- Study on Structure, Stability, and Phase Transformation of Dufulin Polymorphs被引量：9收藏
- 作者：Li, Mengnan Gong, Chengyu Ren, Guobin Xu, Xiaoyong Hong, Minghuang Li, Zhong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2021
- 关键词：Agriculture - Solubility - Density functional theory - Viruses - X ray diffraction - Antiviral agents - Crystalline materials - Phase transitions - Polymorphism - Stability - Thermoanalysis - Losses
- Colorful Prothionamide Salt Forms with Enhancement in Water Solubility and Dissolution Behavior被引量：9收藏
- 作者：Ji, Wei-Jie Jiang, Jun-Yi Hong, Minghuang Zhu, Bin Ren, Guo-Bin Qi, Ming-Hui
- 机构：East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2023
- 关键词：Dissolution - Drug delivery - Free energy - Molecular orbitals - Naphthalene - Salts - Solubility
- Novel Salts of the Atypical Antipsychotic Drug Lurasidone with Improved Solubility and Bioavailability被引量：9收藏
- 作者：Guo, Chunyang Wang, Yuan Xie, Junyi Zhu, Bin Qi, Ming-Hui Hong, Minghuang Ren, Guo-Bin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2023
- 关键词：Biochemistry - Drug delivery - Single crystals - Solubility - Thermoanalysis - X ray diffraction
- Investigation of a solution-mediated phase transformation of pranlukast DMF solvate to hemihydrate被引量：6收藏
- 作者：Hong, Minghuang Chen, Jingyan Zhou, Hui Xu, Hao Ren, Guobin
- 机构：East China Univ Sci & Technol
- 来源：CRYSTAL RESEARCH AND TECHNOLOGY 2017
- 关键词：Pranlukast polymorphism solution-mediated phase transformation
- Four solid forms of flibanserin: Insight into the crystal structures, properties, stability, and solid-state transition被引量：6收藏
- 作者：Qi, Ming-Hui Ye, Wen-Xin Ji, Wei-Jie Hong, Ming-Huang Ren, Guo-Bin
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF MOLECULAR STRUCTURE 2020
- 关键词：Flibanserin Solid form Crystal structure Solid-state transition Stability
- Insight into the behavior regulation of drug transfer of nimodipine loaded PLGA microspheres by emulsion evaporation method被引量：5收藏
- 作者：Yang, Qingqing Bian, Yizhen Ren, Guobin Hong, Minghuang
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：COLLOIDS AND SURFACES A-PHYSICOCHEMICAL AND ENGINEERING ASPECTS 2023
- 关键词：Emulsion evaporation Drug transfer Solvent volatilization Crystallization Drug loading
- Enhancement of solubility and dissolution rate of dipyridamole by salifying: Preparation, characterization, and theoretical calculation被引量：5收藏
- 作者：Yi, Dongxu Dong, Yuhang Yao, Yichen Hong, Minghuang Zhu, Bin Ren, Guo-Bin Qi, Ming-Hui
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF MOLECULAR STRUCTURE 2024
- 关键词：Dipyridamole Salt Solubility Fluorescence
- Conformation, virtual cocrystal screening, synthesis and determination of dipyridamole被引量：5收藏
- 作者：Yi, Dongxu Dong, Yuhang Qi, Minghui Hong, Minghung Zhu, Bin Ren, Guobin
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF MOLECULAR STRUCTURE 2024
- 关键词：Dipyridamole Conformation Virtual cocrystal screening
- Insight into the Structure and Property Diversity of Four Nicorandil Oxalate Salt Polymorphs Based on Experiments and Quantum Chemistry Study被引量：3收藏
- 作者：Wang, Qinglin Guo, Chunyang Qi, Ming-Hui Zhu, Bin Ren, Guo-Bin Hong, Minghuang
- 机构：East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2024
- 关键词：Binding energy - Crystal structure - Dissolution - Nickel compounds - Oxalic acid - Quantum chemistry - Single crystals - Solvents - Structural properties
- Solubility Measurement and Dynamic Simulation Analysis of the Brivaracetam Form A in 12 Pure Solvents被引量：3收藏
- 作者：Wu, Yue Shao, Jia-Hui Zhu, Bin Hong, Minghuang Ren, Guo-Bin Qi, Ming-Hui
- 机构：Shanghai Frontiers Sci Ctr Optogenet Tech Cell Met;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF CHEMICAL AND ENGINEERING DATA 2025
- 关键词：Hydrogen bonds - Molecular dynamics - Solubility
- Insight into the Relationship of Aqueous Solubility and Single-Crystal Structure of Harmine's New Organic Salt Forms被引量：3收藏
- 作者：Hong, Minghuang Wu, Nan Wang, Qinglin Zhou, Rong Zhu, Bin Qi, Ming-Hui Ren, Guo-Bin
- 机构：East China Univ Sci & Technol
- 来源：CRYSTAL GROWTH & DESIGN 2024
- 关键词：Crystal structure - Hardness - Hydration - Hydrogen bonds - Ions - Meats - Molecules - Single crystals - Solubility
- Preparation, characterization, and crystal structures of novel sophocarpine salts with improvements on stability and solubility被引量：2收藏
- 作者：Wang, Yuan Qian, Yi-Hui Hong, Ming-Huang Zhu, Bin Ren, Guo-Bin Qi, Ming -Hui
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF MOLECULAR STRUCTURE 2023
- 关键词：Crystal engineering Crystal structure Stability Thermal properties Sophocarpine
- A novel anion replaced gemini surfactant: Investigation on the primary interaction between gemini surfactant and BSA被引量：1收藏
- 作者：Jin, Yuhao Wu, Qi Yang, Ke Xu, Qianlin Bian, Yizhen Qi, Ming-Hui Zhu, Bin Ren, Guo-Bin Hong, Minghuang
- 机构：East China Univ Sci & Technol
- 来源：COLLOIDS AND SURFACES B-BIOINTERFACES 2025
- 关键词：Gemini surfactant Bovine serum albumin Electrostatic interaction Hydrophobic interaction
