成果/Result
- In Silico Prediction of Chemical Acute Oral Toxicity Using MultiClassification Methods被引量：147收藏
- 作者：Li, Xiao Chen, Lei Cheng, Feixiong Wu, Zengrui Bian, Hanping Xu, Congying Li, Weihua Liu, Guixia Shen, Xu Tang, Yun
- 机构：E China Univ Sci & Technol;Chinese Acad Sci
- 来源：JOURNAL OF CHEMICAL INFORMATION AND MODELING 2014
- 关键词：Risk assessment - Binary trees - Decision trees - Nearest nEIghbor search - Environmental Protection Agency - Barium compounds - Support vector machines
- Bright, Stable, and Biocompatible Organic Fluorophores Absorbing/Emitting in the Deep Near-Infrared Spectral Region被引量：142收藏
- 作者：Lei, Zuhai Li, Xinran Luo, Xiao He, Haihong Zheng, Jing Qian, Xuhong Yang, Youjun
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2017
- 关键词：fluorophores imaging near-infrared
- Asymmetric Intramolecular Oxa-Michael Reactions of Cyclohexadienones Catalyzed by a Primary Amine Salt被引量：106收藏
- 作者：Wu, Wenbin Li, Xin Huang, Huicai Yuan, Xiaoqian Lu, Junzhu Zhu, Kailong Ye, Jinxing
- 机构：E China Univ Sci & Technol
- 来源：ANGEWANDTE CHEMIE-INTERNATIONAL EDITION 2013
- 关键词：asymmetric catalysis cyclohexadienones iminium activation Michael addition primary amine salt
- In silico prediction of serious eye irritation or corrosion potential of chemicals被引量：40收藏
- 作者：Wang, Qin Li, Xiao Yang, Hongbin Cai, Yingchun Wang, Yinyin Wang, Zhuang Li, Weihua Tang, Yun Liu, Guixia
- 机构：East China Univ Sci & Technol
- 来源：RSC ADVANCES 2017
- 关键词：Health hazards - Chemical hazards - Synthetic aperture radar - Forecasting - Learning systems
- Enantioselective organocatalytic phospha-Michael reaction of α,β-unsaturated aldehydes被引量：39收藏
- 作者：Luo, Xiaoyan Zhou, Zhiqiang Li, Xin Liang, Xinmiao Ye, Jinxing
- 机构：E China Univ Sci & Technol
- 来源：RSC ADVANCES 2011
- 关键词：Aldehydes - addition reactions - Phosphorus compounds
- Catalytic Asymmetric Formal Aza-Diels-Alder Reactions of α,β-Unsaturated Ketones and 3H-Indoles被引量：20收藏
- 作者：Hu, Haoxiang Meng, Chunna Dong, Yun Li, Xin Ye, Jinxing
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：ACS CATALYSIS 2015
- 关键词：asymmetric catalysis amine aza-Diels-Alder cycloaddition piperidinone bifunctional catalyst
- Succinate antagonizes α-ketoglutarate biosynthesis governing myeloid differentiation in normal hematopoiesis and myelodysplastic syndromes被引量：14收藏
- 作者：Zhang, Lingling Liu, Leiming Wang, Yue Wang, Aoxue Tang, Weitao Song, Yike Zhang, Zhuo Chen, Yaqiong Liao, Dandan Liang, Huixian Yang, Fan Liu, Yiming Zhou, Jiaying Xuan, Yan Yao, Ke Hu, Zeping Sun, Leimin Chen, Dan He, Ruikun Zhang, Yihan Zou, Yejun Yang, Hui Yang, Yi Li, Xie Zhao, Yuzheng Ju, Zhenyu
- 机构： Department of Hematology; Key Laboratory of Artificial Organs and Computational Medicine; Optogenetics & Synthetic Biology Interdisciplinary Research Center; Research Unit of New Techniques for Live-cell Metabolic Imaging; Key Laboratory of Regenerative Medicine of Ministry of Education
- 来源：Science Bulletin 2026
- Catalyst-free chemoselective α-sulfenylation/β-thiolation for α,β-unsaturated carbonyl compounds被引量：13收藏
- 作者：Huang, Xi Li, Juan Li, Xiang Wang, Jiayi Peng, Yanqing Song, Gonghua
- 机构：East China Univ Sci & Technol
- 来源：RSC ADVANCES 2019
- 关键词：Transition metals - Carbonyl compounds - Chemical reactions - Unsaturated compounds - Catalysts
- Copper-Catalyzed Three-Component Reactions of α-Ketoaldehyde, 1,3-Dicarbonyl Compound, and Organic Boronic Acid in Water: A Route to 1,4-Diketones被引量：10收藏
- 作者：Xia, Qi Li, Xiang Fu, Xi Zhou, Yaxuan Peng, Yanqing Wang, Jiayi Song, Gonghua
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF ORGANIC CHEMISTRY 2021
- 关键词：Catalysis - Copper
- Regioselective and diastereodivergent organocatalytic asymmetric vinylogous Michael addition被引量：9收藏
- 作者：Zou, Chuncheng Lv, Yanting Lu, Min Li, Xin Zhang, Lei Yang, Lei Liu, Zhen Ke, Yanxiong Song, Gonghua Ye, Jinxing
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：ORGANIC CHEMISTRY FRONTIERS 2021
- 关键词：Stereoselectivity - addition reactions - Regioselectivity - Hydrogen bonds
- Simultaneous quantification of intracellular pH and lactate at the single-cell level using a genetically encoded fluorescence lifetime biosensor被引量：1收藏
- 作者：Zhou, Huangmei Zou, Yejun Song, Yike Zhang, Zhuo Chen, Kai Deng, Lunhua Li, Xie Zhang, Sanjun Zhao, Yuzheng
- 机构：East China Normal Univ;East China Univ Sci & Technol;Tongji Univ;Chinese Acad Med Sci;Shanxi Univ
- 来源：SENSORS AND ACTUATORS B-CHEMICAL 2025
- 关键词：Genetically encoded fluorescent biosensors Fluorescent protEIns Fluorescence lifetime imaging Lactate metabolism pH homeostasis
- Novel Combination Therapy for Heart Failure: Trimebutine-Methoxsalen Identified through Synergistic Network Virtual Screening and Experimental Validation被引量：1收藏
- 作者：Huang, Yunyuan Chen, Xin Yang, Jin Yao, Yue Wang, Manjiong Lu, Taotao Li, Xiao Wang, Jiqun Qiao, Sicong Shi, Donglei Li, Xiaokang Li, Jian Xu, Yixiang
- 机构：Cent China Normal Univ;Jinan Univ;East China Univ Sci & Technol;Hainan Univ
- 来源：JOURNAL OF CHEMICAL INFORMATION AND MODELING 2024
- 关键词：Cardiology - Diagnosis - Disease control - Drug therapy
- Synthetic yeast-bacterium consortium enables co-inducible relayed synthesis of chemicals被引量：0收藏
- 作者：Xu, Mingqiang Yu, Jiahui Chen, Xinjie Li, Xie Guo, Yan Qian, Zhilan Liu, Qi Ren, Yanna Lu, Jian Chen, Xianjun Yang, Yi Cai, Menghao
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：METABOLIC ENGINEERING 2026
- 关键词：Synthetic consortiums Co-inducible Quorum sensing Optogenetics Komagataella phaffii Escherichia coli
- Prediction of Intravenous Pharmacokinetic Parameters across Multiple Species by a Multifidelity Deep Learning Framework被引量：0收藏
- 作者：Fang, Jiaojiao Gong, Changda Zhu, Keyun Li, Xiang Yang, Chen Zhang, Zhixing Liu, Guixia Tang, Yun Li, Weihua
- 机构：East China Univ Sci & Technol
- 来源：JOURNAL OF CHEMICAL INFORMATION AND MODELING 2026
- 关键词：Decision making - Deep learning - Forecasting - Learning systems - Mammals - Optimization - Screening - Transfer learning
- Hydroxyl-radical-specific cascade photogeneration for oxygen-chain photocatalytic therapy被引量：0收藏
- 作者：Liu, Qiang Yan, Chenxu Li, Xie Huang, Haiyang Fan, Zheyu Zhang, Jizhan Zhang, Weiwei Shi, Ping Zhao, Yuzheng Guo, Zhiqian Zhu, Wei-Hong
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：CHEMICAL SCIENCE 2026
- 关键词：Chains - Mammals - Molecular oxygen - Photocatalytic activity - Photodynamic therapy - Reaction intermediates - Reactive oxygen species - Scaffolds - Scaffolds (biology)
