成果/Result
- The Mechanism of Acrylamide-Induced Neurotoxicity: Current Status and Future Perspectives被引量：85收藏
- 作者：Zhao, Mengyao Zhang, Boya Deng, Linlin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI
- 来源：FRONTIERS IN NUTRITION 2022
- 关键词：acrylamide neurotoxicity oxidative stress apoptosis and autophagy inflammation gut-brain axis
- Chitooligosaccharides display anti-tumor effects against human cervical cancer cells via the apoptotic and autophagic pathways被引量：57收藏
- 作者：Zhao, Mengyao Gu, Liming Li, Yun Chen, Shumin You, Jiangshan Fan, Liqiang Wang, Yudong Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;SCICBT
- 来源：CARBOHYDRATE POLYMERS 2019
- 关键词：Chitooligosaccharides Enzyme-membrane coupling reactor Apoptosis ROS production Autophagy
- Insights into the nanofiltration separation mechanism of monosaccharides by molecular dynamics simulation被引量：49收藏
- 作者：Yao, Lei Qin, Zhen Chen, Qiming Zhao, Mengyao Zhao, Hefei Ahmad, Waheed Fan, Liqiang Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SC;Univ Nebraska
- 来源：SEPARATION AND PURIFICATION TECHNOLOGY 2018
- 关键词：Monosaccharide Nanofiltration Molecular dynamics simulation Diffusion coefficient Interaction energy
- Current innovations in nutraceuticals and functional foods for intervention of non-alcoholic fatty liver disease被引量：38收藏
- 作者：Zhao, Mengyao Chen, Shumin Ji, Xiaoguo Shen, Xin You, Jiangshan Liang, Xinyi Yin, Hao Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Changzheng Hosp;Shandong Univ Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SC
- 来源：PHARMACOLOGICAL RESEARCH 2021
- 关键词：Functional food Nutraceutical Phytochemical NAFLD Gut microbiota
- Absorption Characteristics of Chitobiose and Chitopentaose in the Human Intestinal Cell Line Caco-2 and Everted Gut Sacs被引量：37收藏
- 作者：Chen, Ping Zhao, Mengyao Chen, Qiming Fang, Liqiang Gao, Feng Zhao, Liming
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;SCICBT
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2019
- 关键词：chitooligosaccharide everted gut sac model intestinal absorption Caco-2 cell model glucose transporter 2 (GLUT2)
- The involvement of oxidative stress, neuronal lesions, neurotransmission impairment, and neuroinflammation in acrylamide-induced neurotoxicity in C57/BL6 mice被引量：33收藏
- 作者：Zhao, Mengyao Deng, Linlin Lu, Xiaoxuan Fan, Liqiang Zhu, Yang Zhao, Liming
- 机构：East China Univ Sci & Technol;Wageningen Univ & Res
- 来源：ENVIRONMENTAL SCIENCE AND POLLUTION RESEARCH 2022
- 关键词：Acrylamide Oxidative stress Neurotoxicity Neurotransmission impairment Neuroinflammation NLRP3 inflammasome
- Chitobiose alleviates oleic acid-induced lipid accumulation by decreasing fatty acid uptake and triglyceride synthesis in HepG2 cells被引量：29收藏
- 作者：Li, Xiaodan Zhao, Mengyao Fan, Liqiang Cao, Xuni Chen, Liehuan Chen, Junhui Lo, Y. Martin Zhao, Liming
- 机构：East China Univ Sci & Technol;Fuzhou Univ;Huizhou Long Dragon Biotechnol Co Ltd;Peking Univ
- 来源：JOURNAL OF FUNCTIONAL FOODS 2018
- 关键词：Chitobiose Hepatic steatosis Oleic acid CD36 DGAT2
- Detection of the 5-hydroxymethylfurfural content in roasted coffee using machine learning based on near-infrared spectroscopy被引量：28收藏
- 作者：Xie, Chuanqi Wang, Changyan Zhao, Mengyao Zhou, Weidong
- 机构：Zhejiang Acad Agr Sci;East China Univ Sci & Technol
- 来源：FOOD CHEMISTRY 2023
- 关键词：NIR spectroscopy Roasted coffee 5-hydroxymethylfurfural Machine learning Content prediction
- Acrylamide induces intrinsic apoptosis and inhibits protective autophagy via the ROS mediated mitochondrial dysfunction pathway in U87-MG cells被引量：26收藏
- 作者：Deng, Linlin Zhao, Mengyao Cui, Yanan Xia, Quanming Jiang, Lihua Yin, Hao Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SC;Shanghai Changzheng Hosp
- 来源：DRUG AND CHEMICAL TOXICOLOGY 2022
- 关键词：Acrylamide oxidative stress NF-kappa B activation intrinsic apoptosis protective autophagy
- Chitooligosaccharide plays essential roles in regulating proline metabolism and cold stress tolerance in rice seedlings被引量：22收藏
- 作者：Zhang, Yang Fan, Liqiang Zhao, Mengyao Chen, Qiming Qin, Zhen Feng, Zhihang Fujiwara, Toru Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SC;Univ Tokyo
- 来源：ACTA PHYSIOLOGIAE PLANTARUM 2019
- 关键词：Chitooligosaccharide Rice seedlings Cold stress Glutamate synthesis Proline metabolism
- Bioactive Indolyl Diketopiperazines from the Marine Derived EndophyticAspergillusversicolorDY180635被引量：21收藏
- 作者：Ding, Yi Zhu, Xiaojing Hao, Liling Zhao, Mengyao Hua, Qiang An, Faliang
- 机构：East China Univ Sci & Technol
- 来源：MARINE DRUGS 2020
- 关键词：endophyte fungus Aspergillus versicolor diketopiperazines ECD calculation enantiomers
- Modulation of tryptophan metabolism via AHR-IL22 pathway mediates the alleviation of DSS-induced colitis by chitooligosaccharides with different degrees of polymerization被引量：21收藏
- 作者：Wang, Yu Ji, Xiaoguo Zhao, Mengyao Li, Juan Yin, Hao Jin, Jiayang Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Changzheng Hosp;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI;Shanghai Frontiers Sci Ctr Optogenet Tech Cell Met
- 来源：CARBOHYDRATE POLYMERS 2023
- 关键词：Colitis IDO1 AHR-IL-22 Tryptophan metabolism Chitooligosaccharides
- Chitooligosaccharide supplementation prevents the development of high fat diet-induced non-alcoholic fatty liver disease (NAFLD) in mice via the inhibition of cluster of differentiation 36 (CD36)被引量：20收藏
- 作者：Zhao, Mengyao Shen, Xin Li, Xiaodan Chen, Baoli Fan, Liqiang Xia, Quanming Zhao, Liming
- 机构：East China Univ Sci & Technol;SCICBT
- 来源：JOURNAL OF FUNCTIONAL FOODS 2019
- 关键词：Chitooligosaccharide Cluster of differentiation 36 (CD36) Non-alcoholic fatty liver disease (NAFLD) Free fatty acids uptake Triglyceride synthesis
- CD36 and DGAT2 facilitate the lipid-lowering effect of chitooligosaccharides via fatty acid intake and triglyceride synthesis signaling被引量：19收藏
- 作者：Shen, Xin Liang, Xinyi Ji, Xiaoguo You, Jiangshan Zhuang, Xinye Song, Yudong Yin, Hao Zhao, Mengyao Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Changzheng Hosp;Shanghai Collaborat Innovat Ctr Biomfg Technol SC
- 来源：FOOD & FUNCTION 2021
- 关键词：Biosynthesis - Cholesterol - Proteins - Mammals
- effects of chitooligosaccharides on the rebalance of gut microorganisms and their metabolites in patients with nonalcoholic fatty liver disease被引量：18收藏
- 作者：Ji, Xiaoguo Chen, Mai Zhao, Mengyao Song, Yudong Lin, Yong Yin, Hao Zhao, Liming
- 机构：East China Univ Sci & Technol;Second Mil Med Univ;Second Mil Med Univ;Shanghai Collaborat Innovat Ctr Biomfg Technol SC
- 来源：JOURNAL OF FUNCTIONAL FOODS 2021
- 关键词：Chitooligosaccharides In vitro fermentation Gut microbes Metabolites Nonalcoholic fatty liver Short-chain fatty acids
- Suppression of GOLM1 by EGCG through HGF/HGFR/AKT/GSK-3β/β-catenin/c-Myc signaling pathway inhibits cell migration of MDA-MB-231被引量：17收藏
- 作者：Xie, Ling Yi, Jun Song, Yongjia Zhao, Mengyao Fan, Liqiang Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SC
- 来源：FOOD AND CHEMICAL TOXICOLOGY 2021
- 关键词：GOLM1 Epigallocatechin-3-Gallate Migration MDA-MB-231
- Acrylamide induces neurotoxicity in zebrafish (Danio rerio) via NLRP3-mediated pyroptosis被引量：17收藏
- 作者：Zhang, Boya Zhao, Mengyao Ji, Xiaoguo Xia, Quanming Jiang, Lihua Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI;Shanghai Changzheng Hosp;East China Univ Sci & Technol
- 来源：SCIENCE OF THE TOTAL ENVIRONMENT 2023
- 关键词：Acrylamide Zebrafish Neurotoxicity Pyroptosis NLRP3 inflammasome Caspy -based pathways
- Enhanced Low Molecular Weight Poly-γ-Glutamic Acid Production in Recombinant Bacillus subtilis 1A751 with Zinc Ion被引量：15收藏
- 作者：Jiang, Sijing Fan, Liqiang Zhao, Mengyao Qiu, Yongjun Zhao, Liming
- 机构：East China Univ Sci & Technol;SCICBT
- 来源：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 2019
- 关键词：Recombinant Bacillus subtilis Low molecular weight Poly-gamma-glutamic acid (gamma-PGA) Poly-gamma-glutamic acid synthase pgsBCAE center dot Zn2+
- Construction of chitooligosaccharide-based nanoparticles of pH/redox cascade responsive for co-loading cyclosporin A and AZD9291被引量：15收藏
- 作者：Chen, Shumin Ji, Xiaoguo Zhao, Mengyao Jin, Jiayang Zhang, Haiping Zhao, Liming
- 机构：East China Univ Sci & Technol;Tongji Univ;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI;East China Univ Sci & Technol
- 来源：CARBOHYDRATE POLYMERS 2022
- 关键词：Chitooligosaccharides Drug delivery system AZD9291 Cyclosporin A Nanoparticles
- Prediction of acrylamide content in potato chips using near-infrared spectroscopy被引量：14收藏
- 作者：Xie, Chuanqi Wang, Changyan Zhao, Mengyao Zhao, Liming
- 机构：East China Univ Sci & Technol;Zhejiang Acad Agr Sci;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI
- 来源：SPECTROCHIMICA ACTA PART A-MOLECULAR AND BIOMOLECULAR SPECTROSCOPY 2023
- 关键词：NIR spectroscopy Potato chips Acrylamide Prediction effective wavenumbers
- Acrylamide Induces Neurotoxicity in SH-SY5Y Cells via NLRP3-mediated Pyroptosis被引量：12收藏
- 作者：Zhao, Mengyao Zhang, Boya Deng, Linlin Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SC;Shanghai Frontiers Sci Ctr Optogenet Tech Cell Me
- 来源：MOLECULAR NEUROBIOLOGY 2023
- 关键词：Acrylamide Pyroptosis NLRP3 inflammasome Neuroinflammation
- Targeted modulation of intestinal barrier and mucosal immune-related microbiota attenuates IgA nephropathy progression被引量：10收藏
- 作者：Zhang, Ran Tang, Yuyan Feng, Xiangru Lu, Xiaoxuan Zhao, Mengyao Jin, Jiayang Ji, Xiaoguo He, Haidong Zhao, Liming
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;Fudan Univ;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI
- 来源：GUT MICROBES 2025
- 关键词：IgA nephropathy gut microbiota chitooligosaccharides kidney-gut crosstalk human microbiota-associated mice
- Hyperspectral imaging for predicting and visualizing the acrylamide levels in roasted coffee被引量：9收藏
- 作者：Xie, Chuanqi Tang, Wensheng Wang, Changyan Zhang, Yanchao Zhao, Mengyao
- 机构：Zhejiang Acad Agr Sci;Huangyan Bur Agr & Rural Affairs;East China Univ Sci & Technol;Zhejiang Sci Tech Univ
- 来源：MICROCHEMICAL JOURNAL 2024
- 关键词：Hyperspectral imaging Acrylamide content Roasted coffee Prediction Visualization
- Proteomic profiling of primary astrocytes and co-cultured astrocytes/microglia exposed to acrylamide被引量：8收藏
- 作者：Zhao, Mengyao Dong, Li Zhu, Chunfeng Hu, Xiaosong Zhao, Liming Chen, Fang Chan, Hing Man
- 机构：China Agr Univ;Univ Ottawa;East China Univ Sci & Technol
- 来源：NEUROTOXICOLOGY 2019
- 关键词：Acrylamide Co-cultured cells Neurotoxicity Oxidative stress Primary astrocytes Proteomics
- Chitopentaose inhibits hepatocellular carcinoma by inducing mitochondrial mediated apoptosis and suppressing protective autophagy被引量：7收藏
- 作者：Zhu, Chunfeng Zhao, Mengyao Fan, Liqiang Cao, Xuni Xia, Quanming Zhou, Jiachun Yin, Hao Zhao, Liming
- 机构：East China Univ Sci & Technol;Shandong Univ Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SC;Shanghai Changzheng Hosp
- 来源：BIORESOURCES AND BIOPROCESSING 2021
- 关键词：Chitooligosaccharides Singular DP HCC Apoptosis Autophagy
- effect of chitooligosaccharides with a specific degree of polymerization on multiple targets in T2DM mice被引量：7收藏
- 作者：You, Jiangshan Zhao, Mengyao Chen, Shumin Jiang, Lihua Gao, Shuhong Yin, Hao Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Changzheng Hosp;Shanghai Collaborat Innovat Ctr Biomfg Technol SC
- 来源：BIORESOURCES AND BIOPROCESSING 2022
- 关键词：Chitooligosaccharides Diabetes mellitus Insulin resistance Hypoglycemic effect
- Alginate oligosaccharides improve high-fat induced hepatic steatosis via PGC-1α-mediated lipophagy and fatty acid β-oxidation pathway被引量：7收藏
- 作者：Li, Zhuoyu Zhao, Mengyao Ji, Xiaoguo Fan, Liqiang Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI
- 来源：JOURNAL OF FUNCTIONAL FOODS 2023
- 关键词：Alginate oligosaccharides (AOS) Non-alcoholic fatty liver disease (NAFLD) Lipid -lowering effect PGC-1 alpha
- Identification of characteristic microbes and metabolites in confined environments population被引量：4收藏
- 作者：Feng, Xiangru Zhong, Jiaqian Wang, Jiaming Lu, Xiaoxuan Chen, Yijia Yao, Yanying Ji, Xiaoguo Zhao, Mengyao Jin, Jiayang Li, Juan Zhao, Liming
- 机构：East China Univ Sci & Technol;Naval Med Univ;East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI
- 来源：BRAIN BEHAVIOR AND IMMUNITY 2025
- 关键词：Confined environments Stress Emotional states Gut microbiota Metabolomics
- 工程教育专业认证背景下食品工艺学教学改革探索被引量：4收藏
- 作者：赵梦瑶
- 机构：华东理工大学生物工程学院
- 来源：《高教学刊》 2021
- 关键词：食品工艺学 工程教育认证 课程思政 教学改革
- 摘要：食品工艺学是食品类专业核心课程,强调学生综合能力的培养。以教师讲授为主的传统理论教学常存在基础理论知识传授和学生能力培养脱节的现象,已无法支撑新形势背景下的教学目标和育人任务。在工程教育专业认证背景下,文章对食品工艺学的...
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- The regulatory effect of chitooligosaccharides on islet inflammation in T2D individuals after islet cell transplantation: the mechanism behind Candida albicans abundance and macrophage polarization被引量：4收藏
- 作者：Zhang, Yayu Ji, Xiaoguo Chang, Kunlin Yin, Hao Zhao, Mengyao Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI;Shanghai Frontiers Sci Ctr Optogenet Tech Cell Met;Shanghai Changzheng Hosp
- 来源：GUT MICROBES 2025
- 关键词：Islet cell transplantation islet inflammation chitooligosaccharides macrophages
Candida albicans
