成果/Result
- Comparative performance of two upflow anaerobic biohydrogen-producing reactors seeded with different sludges被引量：53收藏
- 作者：Wang, Yi Mu, Yang Yu, Han-Qing
- 机构：Univ Sci & Technol China;E China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF HYDROGEN ENERGY 2007
- 关键词：acidogenesis H-2 production pH upflow anaerobic sludge blanket (UASB)
- Enhancement of Sulfur Conversion Rate in the Production of L-CystEIne by Engineered Escherichia coli被引量：42收藏
- 作者：Liu, Han Hou, Yehua Wang, Yu Li, Zhimin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2020
- 关键词：Escherichia coli metabolic engineering transcriptional regulator sulfur conversion rate l-cystEIne agricultural/food industries
- Fitness of Chassis Cells and Metabolic Pathways for L-CystEIne Overproduction in Escherichia coli被引量：35收藏
- 作者：Liu, Han Wang, Yu Hou, Yehua Li, Zhimin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2020
- 关键词：Escherichia coli l-cystEIne metabolic engineering chassis cells
- Significantly improved expression and biochemical properties of recombinant serratia marcescens lipase as robust biocatalyst for kinetic resolution of chiral ester被引量：33收藏
- 作者：Wang, Yi Zhao, Jian Xu, Jian-He Fan, Li-Qiang Li, Su-Xia Zhao, Li-Li Mao, Xiao-Bo
- 机构： State Key Laboratory of Bioreactor Engineering
- 来源：Applied Biochemistry and Biotechnology 2010
- 关键词：Esters - Gene expression - Recombinant protEIns - Escherichia coli - fatty acids - Affinity chromatography - Lipases - Substrates - Cloning - Metal ions - Metals - Nonionic surfactants - Purification
- Modulation of tryptophan metabolism via AHR-IL22 pathway mediates the alleviation of DSS-induced colitis by chitooligosaccharides with different degrees of polymerization被引量：21收藏
- 作者：Wang, Yu Ji, Xiaoguo Zhao, Mengyao Li, Juan Yin, Hao Jin, Jiayang Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Changzheng Hosp;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI;Shanghai Frontiers Sci Ctr Optogenet Tech Cell Met
- 来源：CARBOHYDRATE POLYMERS 2023
- 关键词：Colitis IDO1 AHR-IL-22 Tryptophan metabolism Chitooligosaccharides
- An Ultrasensitive, One-Pot RNA Detection Method Based on Rationally Engineered Cas9 Nickase-Assisted Isothermal Amplification Reaction被引量：20收藏
- 作者：Wang, Ting Wang, Yan Chen, Pinru Yin, Bin-Cheng Ye, Bang-Ce
- 机构：East China Univ Sci & Technol;Zhejiang Univ Technol
- 来源：ANALYTICAL CHEMISTRY 2022
- 关键词：Diseases - DNA - Escherichia coli - Genome - Isotherms - RNA - Salmonella - Transcription
- High frequency transformation of the industrial erythromycin-producing bacterium Saccharopolyspora erythraea被引量：18收藏
- 作者：Wang, Yong Wang, YiGuang Zhang, Siliang
- 机构： State Key Laboratory of Bioreactor Engineering; Institute of Medicinal Biotechnology
- 来源：Biotechnology Letters 2008
- 关键词：Bacteria - DNA sequences - Escherichia coli
- Improved production of erythromycin a by expression of a heterologous gene encoding S-adenosylmethionine synthetase被引量：17收藏
- 作者：Wang, Yong Wang, YiGuang Chu, Ju Zhuang, Yingping Zhang, Lixin Zhang, Siliang
- 机构： State Key Laboratory of Bioreactor Engineering; Institute of Medical Biotechnology; Institute of Microbiology; South China Sea Institute of Oceanology; Guangzhou Institute of Biomedicine and Health
- 来源：Applied Microbiology and Biotechnology 2007
- 关键词：Bioassay - Chromosomes - Enzymes - Gene encoding - High performance liquid chromatography
- Enhanced production of avermectin by deletion of type III polyketide synthases biosynthetic cluster rpp in Streptomyces avermitilis被引量：16收藏
- 作者：Meng, L. Xiong, Z. Chu, J. Wang, Y.
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;Univ Shanghai Sci & Technol
- 来源：LETTERS IN APPLIED MICROBIOLOGY 2016
- 关键词：avermectin production biosynthesis cluster industrial overproducer rppA Streptomyces avermitili type III polyketide synthases
- A novel surface-enhanced Raman scattering method for detecting fish pathogenic bacteria with Fe3O4@PEI nanocomposite and concentrated Au@Ag被引量：15收藏
- 作者：Jia, Nan Xiong, Yinran Wang, Ying Lu, Siqian Zhang, Ruoqiu Kang, Yan Du, Yiping
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF RAMAN SPECTROSCOPY 2022
- 关键词：concentrated Au@Ag nanoparticles Fe3O4@PEI fish bacteria LDA SERS
- Study of lincomycin partition in a recyclable thermo-pH responsive aqueous two-phase system被引量：11收藏
- 作者：Wang, Yan Yang, Ting Zeng, Hainan Wan, Junfen Cao, Xuejun
- 机构：East China Univ Sci & Technol
- 来源：PROCESS BIOCHEMISTRY 2021
- 关键词：Aqueous two-phase systems Licomycin pH-responsive polymer Thermo-responsive polymer
- Artificial intelligence-guided fermentation process regulation reveals metabolic rewiring in gentamicin C1a overproduction被引量：10收藏
- 作者：Xu, Feng Su, Lihuan Wang, Yuan Gao, Hao Hu, Kaihao Ben, Rong Guo, Yuanxin Li, Xu Chu, Ju Tian, Xiwei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2025
- 关键词：Fermentation optimization Artificial neural network Multi-sensor monitoring Genetic algorithm Metabolic flux analysis
- Harnessing near-infrared and Raman spectral sensing and artificial intelligence for real-time monitoring and precision control of bioprocess被引量：9收藏
- 作者：Xu, Feng Su, Lihuan Gao, Hao Wang, Yuan Ben, Rong Hu, Kaihao Mohsin, Ali Li, Chao Chu, Ju Tian, Xiwei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2025
- 关键词：Artificial intelligence Near-infrared spectroscopy Raman spectroscopy Bioprocess optimization Gentamicin C1a
- Artificial intelligence-driven fermentation optimization for α-amylase hyperproduction enabled by Raman monitoring and metabolic network analysis被引量：5收藏
- 作者：Wang, Yuan Wang, Yonghong Xu, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2026
- 关键词：Aspergillus niger alpha-amylase production Machine learning Transcriptomic analysis Raman spectroscopy
- Balanced water and heat energy recycling by full evaporation of wastewater (FEW) in dry biorefining processes of lignocellulose biomass被引量：5收藏
- 作者：Wang, Ya Zhang, Bin Liu, Xiucai Bao, Jie
- 机构：Shihezi Univ;East China Univ Sci & Technol;Cathay Biotech Inc
- 来源：WASTE MANAGEMENT 2025
- 关键词：Dry biorefining Lignocellulose biomass Full evaporation of wastewater (FEW) Carbon negative Aspen Plus
- Rigorous Calculation of Greenhouse Gases (GHG) in Sustainable L-lactic Acid Production from Lignocellulosic Biomass based on Advanced Biorefinery Processing Technology被引量：4收藏
- 作者：Wang, Ya Zhang, Bin Bao, Jie
- 机构：Shihezi Univ;East China Univ Sci & Technol
- 来源：ACS SUSTAINABLE CHEMISTRY & ENGINEERING 2025
- 关键词：GHG emission L-lactic acid cornstover dry biorefining wastewater lignincombustion
- A Paradigm of Computer Vision and Deep Learning Empowers the Strain Screening and Bioprocess Detection被引量：3收藏
- 作者：Xu, Feng Su, Lihuan Wang, Yuan Hu, Kaihao Liu, Ling Ben, Rong Gao, Hao Mohsin, Ali Chu, Ju Tian, Xiwei
- 机构：East China Univ Sci & Technol
- 来源：BIOTECHNOLOGY AND BIOENGINEERING 2025
- 关键词：bioprocess detection computer vision deep learning fluorescence intensity gentamicin C1a strain selection
- The c-di-GMP signalling component YfiR regulates multiple bacterial phenotypes and virulence in Pseudomonas plecoglossicida被引量：3收藏
- 作者：Wang, Ying Jin, Yinhua Sun, Fei Zhang, Yuanxing Liu, Qin Wang, Qiyao Yang, Dahai Zhang, Yibei
- 机构：East China Univ Sci & Technol;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines;East China Univ Sci & Technol
- 来源：JOURNAL OF APPLIED MICROBIOLOGY 2023
- 关键词：biofilm c-di-GMP large yellow croaker Pseudomonas plecoglossicida YfiBNR
- Systematic engineering of Micromonospora echinospora cell factory for gentamicin C1a overproduction被引量：1收藏
- 作者：Xu, Feng Gao, Hao Ben, Rong Hu, Kaihao Wang, Yuan Mohsin, Ali Guo, Yuanxin Li, Xu Hang, Haifeng Chu, Ju Tian, Xiwei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：TRENDS IN BIOTECHNOLOGY 2026
- 关键词：Antibiotics - Biochemistry - Biosynthesis - Genes - Metabolism - Optimization
- Effective extraction of tylosin and spiramycin from fermentation broth using thermo-responsive ethylene oxide/propylene oxide aqueous two-phase systems被引量：1收藏
- 作者：Yang, Ting Zheng, Ting Wang, Yan Zhang, Yan He, Dong Zeng, Hainan Wei, Yanli Chen, Xi Wan, Junfen Cao, Xuejun
- 机构：East China Univ Sci & Technol;Shanghai Jiao Tong Univ;Henan Topfond Pharmaceut Co Ltd
- 来源：JOURNAL OF SEPARATION SCIENCE 2022
- 关键词：antibiotics ethylene oxide propylene oxide copolymer molecular dynamic simulation partition coefficient recyclable aqueous two-phase systems
- Metabolic engineering of Bacillus subtilis for high-yield surfactin production被引量：0收藏
- 作者：Wang, Yong Li, Hanqing Mao, Yue Li, Pengfei Wu, Haizhen Ye, Jiang Zhang, Huizhan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIOTECHNOLOGY FOR BIOFUELS AND BIOPRODUCTS 2026
- 关键词：Surfactin Bacillus subtilis Metabolic engineering P43 promoter Tolerance engineering
- Tandem Duplication-Driven Neofunctionalization of UDP-Glycosyltransferases Shapes the Diversification of Triterpenoid Saponins in the Cucurbitaceae被引量：0收藏
- 作者：Wang, Guangyi Li, Mengmeng Dai, Xuehui Zhang, Yanchen Wu, Yuhan Yan, Zhaotao Tian, Chenfei Fan, Hongkai Liu, Haili Zhang, Xiaowei Yang, Yiming Lu, Jiayu Sun, Yuwei Wang, Yong
- 机构：Chinese Acad Sci;Univ Chinese Acad Sci;East China Univ Sci & Technol;Shanghai Tobacco Grp Co Ltd;Shanghai Univ Tradit Chinese Med
- 来源：ADVANCED SCIENCE 2026
- 关键词：comparative genomics cucurbitaceae tandem duplication triterpenoid saponins UDP-glycosyltransferase
- Multilevel cytochrome P450 engineering integrating protEIn language model-guided evolution enables de novo biosynthesis of amentoflavone in Escherichia coli被引量：0收藏
- 作者：Dai, Xuehui Zhu, Jiangming Wu, Zheyu Wang, Guangyi Zhang, Yanchen Tian, Chenfei Ren, Yuhong Liu, Haili Wang, Yong
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;Univ Chinese Acad Sci
- 来源：BIORESOURCE TECHNOLOGY 2026
- 关键词：Amentoflavone Cytochrome P450 ProtEIn language model Metabolic engineering Biflavonoid biosynthesis
- Lipid extraction from oleaginous yeast cells with very high lipid content, low cell density, and fragile cell wall被引量：0收藏
- 作者：Wang, Ya Zhang, Bingyan Principe, Umutumwa E. Zhang, Bin Bao, Jie
- 机构：East China Univ Sci & Technol;Shihezi Univ
- 来源：JOURNAL OF BIOSCIENCE AND BIOENGINEERING 2026
- 关键词：Heat-assisted ultrasonic extraction Modified Folch method Oleaginous yeast Microbial lipid]
- A Non-Contact Electronic Nose System Based on Off-Gas Response for Real-Time NH4+ Monitoring in Fermentation被引量：0收藏
- 作者：Zhang, Xiaoqin Gao, Daqi Wang, Yuan
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：SENSORS 2026
- 关键词：electronic nose non-contact monitoring real-time online monitoring fermentation off-gas gentamicin fermentation NH4+
