成果/Result
- Antibacterial and antibiofilm activities of eugenol from essential oil of Syzygium aromaticum (L.) Merr. & L. M. Perry (clove) leaf against periodontal pathogen Porphyromonas gingivalis被引量：129收藏
- 作者：Zhang, Yi Wang, Yue Zhu, Xiaojing Cao, Ping Wei, Shaomin Lu, Yanhua
- 机构：East China Univ Sci & Technol;Shanghai Inst Technol;Shanghai Jahwa Grp Co Ltd
- 来源：MICROBIAL PATHOGENESIS 2017
- 关键词：Eugenol Porphyromonas gingivalis Cell membrane Biofilm formation
- Complete Biosynthesis of Erythromycin A and Designed Analogs Using E. coli as a Heterologous Host被引量：94收藏
- 作者：Zhang, Haoran Wang, Yong Wu, Jiequn Skalina, Karin Pfeifer, Blaine A.
- 机构：Tufts Univ;E China Univ Sci & Technol
- 来源：CHEMISTRY & BIOLOGY 2010
- Comparative performance of two upflow anaerobic biohydrogen-producing reactors seeded with different sludges被引量：53收藏
- 作者：Wang, Yi Mu, Yang Yu, Han-Qing
- 机构：Univ Sci & Technol China;E China Univ Sci & Technol
- 来源：INTERNATIONAL JOURNAL OF HYDROGEN ENERGY 2007
- 关键词：acidogenesis H-2 production pH upflow anaerobic sludge blanket (UASB)
- Enhancement of Sulfur Conversion Rate in the Production of L-Cysteine by Engineered Escherichia coli被引量：42收藏
- 作者：Liu, Han Hou, Yehua Wang, Yu Li, Zhimin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2020
- 关键词：Escherichia coli metabolic engineering transcriptional regulator sulfur conversion rate l-cysteine agricultural/food industries
- Industrial bioprocess control and optimization in the context of systems biotechnology被引量：38收藏
- 作者：Wang, Yong Chu, Ju Zhuang, Yingping Wang, Yonghong Xia, Jianye Zhang, Siliang
- 机构：E China Univ Sci & Technol
- 来源：BIOTECHNOLOGY ADVANCES 2009
- 关键词：Industrial bioprocess Systems biotechnology Bioprocess control and optimization
- Fitness of Chassis Cells and Metabolic Pathways for L-Cysteine Overproduction in Escherichia coli被引量：35收藏
- 作者：Liu, Han Wang, Yu Hou, Yehua Li, Zhimin
- 机构：East China Univ Sci & Technol;Shanghai Collaborat Innovat Ctr Biomfg Technol
- 来源：JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY 2020
- 关键词：Escherichia coli l-cysteine metabolic engineering chassis cells
- DNA shuffling of methionine adenosyltransferase gene leads to improved S-adenosyl-L-methionine production in Pichia pastoris被引量：34收藏
- 作者：Hu, Hui Qian, Jiangchao Chu, Ju Wang, Yong Zhuang, Yingping Zhang, Siliang
- 机构：E China Univ Sci & Technol
- 来源：JOURNAL OF BIOTECHNOLOGY 2009
- 关键词：S-adenosyl-L-methionine Methionine adenosyltransferase DNA shuffling Pichia pastoris
- Modulation of tryptophan metabolism via AHR-IL22 pathway mediates the alleviation of DSS-induced colitis by chitooligosaccharides with different degrees of polymerization被引量：21收藏
- 作者：Wang, Yu Ji, Xiaoguo Zhao, Mengyao Li, Juan Yin, Hao Jin, Jiayang Zhao, Liming
- 机构：East China Univ Sci & Technol;Shanghai Changzheng Hosp;Shanghai Collaborat Innovat Ctr Biomfg Technol SCI;Shanghai Frontiers Sci Ctr Optogenet Tech Cell Met
- 来源：CARBOHYDRATE POLYMERS 2023
- 关键词：Colitis IDO1 AHR-IL-22 Tryptophan metabolism Chitooligosaccharides
- An Ultrasensitive, One-Pot RNA Detection Method Based on Rationally Engineered Cas9 Nickase-Assisted Isothermal Amplification Reaction被引量：20收藏
- 作者：Wang, Ting Wang, Yan Chen, Pinru Yin, Bin-Cheng Ye, Bang-Ce
- 机构：East China Univ Sci & Technol;Zhejiang Univ Technol
- 来源：ANALYTICAL CHEMISTRY 2022
- 关键词：Diseases - DNA - Escherichia coli - Genome - Isotherms - RNA - Salmonella - Transcription
- Development of bioabsorbable polylactide membrane with controllable hydrophilicity for adjustment of cell behaviours被引量：19收藏
- 作者：Yang, Yang Qiu, Xiaofeng Sun, Yi Wang, Yifeng Wang, Jine Li, Yulin Liu, Changsheng
- 机构：East China Univ Sci & Technol
- 来源：ROYAL SOCIETY OPEN SCIENCE 2018
- 关键词：ring opening polymerization poly(D,L-lactide) membrane amphiphilic poly(ethylene glycol)-b-poly(D,L-lactide) surface hydrophilicity biodegradation cell behaviours
- Enhanced production of avermectin by deletion of type III polyketide synthases biosynthetic cluster rpp in Streptomyces avermitilis被引量：16收藏
- 作者：Meng, L. Xiong, Z. Chu, J. Wang, Y.
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;Univ Shanghai Sci & Technol
- 来源：LETTERS IN APPLIED MICROBIOLOGY 2016
- 关键词：avermectin production biosynthesis cluster industrial overproducer rppA Streptomyces avermitili type III polyketide synthases
- Significantly Improved Expression and Biochemical Properties of Recombinant Serratia marcescens Lipase as Robust Biocatalyst for Kinetic Resolution of Chiral Ester被引量：16收藏
- 作者：Wang, Yi Zhao, Jian Xu, Jian-He Fan, Li-Qiang Li, Su-Xia Zhao, Li-Li Mao, Xiao-Bo
- 机构：E China Univ Sci & Technol
- 来源：APPLIED BIOCHEMISTRY AND BIOTECHNOLOGY 2010
- 关键词：Serratia marcescens ECU1010 Lipase Soluble expression Purification Characterization Enantioselectivity Biocatalytic resolution
- Overcoming multidrug resistance in human carcinoma cells by an antisense oligodeoxynucleotide-doxorubicin conjugate in vitro and in vivo被引量：15收藏
- 作者：Ren, Yuhong Wang, Yong Zhang, Yufei Wei, Dongzhi
- 机构：E China Univ Sci & Technol
- 来源：MOLECULAR PHARMACEUTICS 2008
- 关键词：multidrug resistance antisense oligodeoxynucleotide-doxorubicin conjugate P-glycoprotein KB-A-1 cells
- A novel surface-enhanced Raman scattering method for detecting fish pathogenic bacteria with Fe3O4@PEI nanocomposite and concentrated Au@Ag被引量：15收藏
- 作者：Jia, Nan Xiong, Yinran Wang, Ying Lu, Siqian Zhang, Ruoqiu Kang, Yan Du, Yiping
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：JOURNAL OF RAMAN SPECTROSCOPY 2022
- 关键词：concentrated Au@Ag nanoparticles Fe3O4@PEI fish bacteria LDA SERS
- A novel screen-printed electrode array for rapid high-throughput detection被引量：13收藏
- 作者：Mu, Shuai Wang, Xiao Li, Yuan-Ting Wang, Yang Li, Da-Wei Long, Yi-Tao
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：ANALYST 2012
- Dysregulation of Cytosolic c-di-GMP in Edwardsiella piSCIcida Promotes Cellular Non-Canonical Ferroptosis被引量：13收藏
- 作者：Wen, Ying Wang, Ying Chen, Shouwen Zhou, Xiangshan Zhang, Yuanxing Yang, Dahai Nunez, Gabriel Liu, Qin
- 机构：East China Univ Sci & Technol;Univ Michigan;Univ Michigan;Southern Marine Sci & Engn Guangdong Lab Zhuhai;Shanghai Engn Res Ctr Maricultured Anim Vaccines
- 来源：FRONTIERS IN CELLULAR AND INFECTION MICROBIOLOGY 2022
- 关键词：Edwardsiella piSCIcida c-di-GMP accumulation non-canonical ferroptosis bacterial virulence pathogen infection
- Decrease of hirudin degradation by deleting the KEXI gene in recombinant Pichia pastoris被引量：12收藏
- 作者：Ni, Zhenhua Zhou, Xiangshan Sun, Xueqian Wang, Ya Zhang, Yuanxing
- 机构：E China Univ Sci & Technol
- 来源：YEAST 2008
- 关键词：pop-in/pop-out gene deletion Pichia pastoris hirudin degradation
- Targeting expression of the catalytic domain of the kinase insert domain receptor (KDR) in the peroxisomes of Pichia pastoris被引量：11收藏
- 作者：Wang, Ya Xuan, Yaoji Zhang, Ping Jiang, Xi Ni, Zhenhua Tong, Linjiang Zhou, Xiangshan Lin, Liping Ding, Jian Zhang, Yuanxing
- 机构：E China Univ Sci & Technol;Chinese Acad Sci
- 来源：FEMS YEAST RESEARCH 2009
- 关键词：KDR kinase insert domain receptor peroxisome phosphorylation Pichia pastoris vascular endothelial growth factor receptor 2
- Study of lincomycin partition in a recyclable thermo-pH responsive aqueous two-phase system被引量：11收藏
- 作者：Wang, Yan Yang, Ting Zeng, Hainan Wan, Junfen Cao, Xuejun
- 机构：East China Univ Sci & Technol
- 来源：PROCESS BIOCHEMISTRY 2021
- 关键词：Aqueous two-phase systems Licomycin pH-responsive polymer Thermo-responsive polymer
- Artificial intelligence-guided fermentation process regulation reveals metabolic rewiring in gentamicin C1a overproduction被引量：10收藏
- 作者：Xu, Feng Su, Lihuan Wang, Yuan Gao, Hao Hu, Kaihao Ben, Rong Guo, Yuanxin Li, Xu Chu, Ju Tian, Xiwei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2025
- 关键词：Fermentation optimization Artificial neural network Multi-sensor monitoring Genetic algorithm Metabolic flux analysis
- Expansion of mouse sertoli cells on microcarriers被引量：9收藏
- 作者：Shi, B. Wang, Y. Zhuang, Y. Chu, J. Zhang, S. Shi, X. Bi, J. Guo, M.
- 机构：E China Univ Chem Technol;Capital Med Univ;Univ Adelaide
- 来源：CELL PROLIFERATION 2010
- Harnessing near-infrared and Raman spectral sensing and artificial intelligence for real-time monitoring and precision control of bioprocess被引量：9收藏
- 作者：Xu, Feng Su, Lihuan Gao, Hao Wang, Yuan Ben, Rong Hu, Kaihao Mohsin, Ali Li, Chao Chu, Ju Tian, Xiwei
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2025
- 关键词：Artificial intelligence Near-infrared spectroscopy Raman spectroscopy Bioprocess optimization Gentamicin C1a
- Esre: A novel essential non-coding RNA in Escherichia coli被引量：8收藏
- 作者：Chen, Zhichao Wang, Yi Li, Yarong Li, Yue Fu, Nan Ye, Jiang Zhang, Huizhan
- 机构：E China Univ Sci & Technol
- 来源：FEBS LETTERS 2012
- 关键词：Escherichia coli sRNA Essential sRNA Esre yigP
- Heterologous expression of chaperones from hyperthermophilic archaea inhibits aminoglycoside-induced protein misfolding in Escherichia coli被引量：6收藏
- 作者：Peng, S. Chu, Z. Lu, J. Li, D. Wang, Y. Yang, S. Zhang, Y.
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;Chinese Acad Sci
- 来源：BIOCHEMISTRY-MOSCOW 2017
- 关键词：aminoglycoside protein mistranslation Escherichia coli hyperthermophilic archaeon Pyrococcus furiosus chaperone
- Recent advances in the biosynthesis and production optimization of gentamicin: A critical review被引量：6收藏
- 作者：Xu, Feng Hu, Kaihao Mohsin, Ali Wu, Jie Su, Lihuan Wang, Yuan Ben, Rong Gao, Hao Tian, Xiwei Chu, Ju
- 机构：East China Univ Sci & Technol
- 来源：SYNTHETIC AND SYSTEMS BIOTECHNOLOGY 2025
- 关键词：Micromonospora Gentamicin biosynthesis Fermentation process optimization Molecular regulation Aminoglycosides
- Balanced water and heat energy recycling by full evaporation of wastewater (FEW) in dry biorefining processes of lignocellulose biomass被引量：5收藏
- 作者：Wang, Ya Zhang, Bin Liu, Xiucai Bao, Jie
- 机构：Shihezi Univ;East China Univ Sci & Technol;Cathay Biotech Inc
- 来源：WASTE MANAGEMENT 2025
- 关键词：Dry biorefining Lignocellulose biomass Full evaporation of wastewater (FEW) Carbon negative Aspen Plus
- Artificial intelligence-driven fermentation optimization for α-amylase hyperproduction enabled by Raman monitoring and metabolic network analysis被引量：5收藏
- 作者：Wang, Yuan Wang, Yonghong Xu, Feng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：BIORESOURCE TECHNOLOGY 2026
- 关键词：Aspergillus niger alpha-amylase production Machine learning Transcriptomic analysis Raman spectroscopy
- Rigorous Calculation of Greenhouse Gases (GHG) in Sustainable L-lactic Acid Production from Lignocellulosic Biomass based on Advanced Biorefinery Processing Technology被引量：4收藏
- 作者：Wang, Ya Zhang, Bin Bao, Jie
- 机构：Shihezi Univ;East China Univ Sci & Technol
- 来源：ACS SUSTAINABLE CHEMISTRY & ENGINEERING 2025
- 关键词：GHG emission L-lactic acid cornstover dry biorefining wastewater lignincombustion
- Gymnosperm-specific CYP90Js enable biflavonoid biosynthesis and microbial production of amentoflavone被引量：4收藏
- 作者：Dai, Xue-Hui Zhu, Jiang-Ming Wang, Guang-Yi Ren, Yu-Hong Liu, Hai-Li Wang, Yong
- 机构：Chinese Acad Sci;East China Univ Sci & Technol;Univ Chinese Acad Sci
- 来源：NATURE COMMUNICATIONS 2025
- Metabolic engineering of Escherichia coli for squalene overproduction被引量：3收藏
- 作者：Zhu, Jiangming Mao, Yaping Mo, Hongchun Dai, Xuehui Wu, Yuhan Wang, Guangyi Feng, Zhanguang Yue, Ruirui Wei, Dongzhi Liu, Haili Wang, Yong
- 机构：East China Univ Sci & Technol;Chinese Acad Sci;Univ Chinese Acad Sci;Henan Univ
- 来源：SYNTHETIC AND SYSTEMS BIOTECHNOLOGY 2025
- 关键词：Squalene Escherichia coli Metabolic engineering Targeted lipidomics
