成果/Result
- Combination of atmospheric and room temperature plasma (ARTP) mutagenesis, genome shuffling and dimethyl sulfoxide (DMSO) feeding to improve FK506 production in Streptomyces tsukubaensis被引量：17收藏
- 作者：Ye, Liting Ye, Ruifang Hu, Fengxian Wang, Guozhu
- 机构：East China Univ Sci & Technol
- 来源：BIOTECHNOLOGY LETTERS 2021
- 关键词：Streptomyces tsukubaensis ARTP mutation Genome shuffling DMSO
- Lincomycin, rational selection of high producing strain and improved fermentation by amino acids supplementation被引量：10收藏
- 作者：Ye, Ruifang Wang, Qian Zhou, Xiaofang
- 机构：E China Univ Sci & Technol
- 来源：BIOPROCESS AND BIOSYSTEMS ENGINEERING 2009
- 关键词：Lincomycin Rational screening Propylproline Amino acids Metabolic engineering
- Simultaneous improvement of lincomycin A production and reduction of lincomycin B levels in Streptomyces lincolnensis using a combined medium optimization approach被引量：9收藏
- 作者：Zheng, Xiu-hong Ye, Rui-fang Ding, Qi-hang Hu, Feng-xian Zhang, Hong-zhou Lai, Shen
- 机构：East China Univ Sci & Technol;Topfond Pharmaceut Co Ltd
- 来源：ANNALS OF MICROBIOLOGY 2022
- 关键词：Streptomyces lincolnensis Lincomycin Medium optimization Osmotic stress qRT-PCR
- Impact of a novel precursor on FK506 production and key gene transcription in Streptomyces tsukubaensis No. 9993被引量：7收藏
- 作者：Sun, Yan Ye, Ruifang
- 机构：E China Univ Sci & Technol
- 来源：RESEARCH ON CHEMICAL INTERMEDIATES 2016
- 关键词：FK506 Salicyl alcohol RT-qPCR Gene transcription Fermentation
- Increasing Demeclocycline Production in Streptomyces aureofaciens by Manipulating the Expression of a Novel SARP Family Regulator and Its Genes被引量：5收藏
- 作者：Tan, Yan-Ying Zhu, Guang-Yao Ye, Rui-Fang Zhang, Hong-Zhou Zhu, De-Yu
- 机构：East China Univ Sci & Technol;Topfond Pharmaceut Co Ltd
- 来源：BIOTECHNOLOGY AND BIOPROCESS ENGINEERING 2021
- 关键词：demeclocycline Streptomyces aureofaciens SARP family regulator resistance gene
- Improvement of lincomycin production by mutant selection and metabolic regulation被引量：4收藏
- 作者：Pang, Xuewei Zheng, Yitao Qiao, Xianting Mao, Quangui Ma, Qian Ye, Ruifang
- 机构：East China Univ Sci & Technol;Topfond Pharmaceut Co Ltd
- 来源：PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY 2017
- 关键词：Bioreactor lincomycin mutant propylproline two-dimensional gel electrophoresis
- Learning from Competition: An Outcome-Based Introductory Activity for First-Year Biotechnology Undergraduates被引量：4收藏
- 作者：Zhang, Xiaoyan Ye, Ruifang Hu, Fengxian Zheng, Yitao Gao, Shuhong Zhuang, Yingping Wang, Qiyao Bai, Yunpeng
- 机构：East China Univ Sci & Technol;East China Univ Sci & Technol
- 来源：AMERICAN BIOLOGY TEACHER 2019
- 关键词：First-year undergraduate interdiSCIplinary discovery learning biotechnology
- Amplification of lmbB1 gene in Streptomyces lincolnensis improves quantity and quality of lincomycin A fermentation被引量：4收藏
- 作者：Yang, Jing Ye, Ruifang Zhang, Hongzhou Liu, Yan
- 机构：East China Univ Sci & Technol;Topfond Pharmaceut Co Ltd
- 来源：PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY 2020
- 关键词：Lincomycin lmbB1 secondary metabolite Streptomyces lincolnensis
- EFFECTS OF PRECURSORS ON KITASAMYCIN PRODUCTION IN Streptomyces kitasatoensis被引量：3收藏
- 作者：Zheng, Xiong Ye, Ruifang Ho, Fengxian Mao, Quangui Zhang, Hongzhou
- 机构：East China Univ Sci & Technol;Topfond Pharmaceut Co Ltd
- 来源：BIOSCIENCE JOURNAL 2019
- 关键词：Streptomyces kitasatoensis Ethylacetate Fermentation Component Kitasamycin
- Strain screening and sodium lactate effect on spiramycin production in Streptomyces spiramyceticus被引量：2收藏
- 作者：Zeng, Jun Ye, Rui-Fang Zheng, Yi-Tao Mao, Quan-Gui Lv, He-Ping Shi, Ting-Ting
- 机构：E China Univ Sci & Technol
- 来源：RESEARCH ON CHEMICAL INTERMEDIATES 2016
- 关键词：Streptomyces spiramyceticus Spiramycin Sodium lactate Sodium lactate tolerant mutant Fermentation
- Influence of Al3+ on the titer of spiramycin and effective components in fermentor被引量：1收藏
- 作者：Li, Zhen Hu, Fengxian Ye, Ruifang Lv, Heping Zeng, Jun
- 机构：East China Univ Sci & Technol;Topfond Pharmaceut Co Ltd
- 来源：PREPARATIVE BIOCHEMISTRY & BIOTECHNOLOGY 2017
- 关键词：Al3+ Streptomyces spiramyceticus 16-10-2 Spiramycin
- Synthesis and glucoamylase immobilization of SiO2 monolithic carriers by addition of Gelatin/PEG被引量：0收藏
- 作者：Wang Yan-Fang Chen Qi Ye Rui-Fang Song Li Zhang Jin-Chao Hou Feng-Zhen
- 机构：E China Univ Sci & Technol;E China Univ Sci & Technol;E China Univ Sci & Technol
- 来源：CHINESE JOURNAL OF INORGANIC CHEMISTRY 2007
- 关键词：porous SiO2 gelatin sol-gel enzyme carrier
